Sentences with phrase «regulatory systems develop»

Moreover, at birth the infant's breathing i.e. respiratory system is also not yet fully developed, as regards complete control of both voluntary and involuntary breathing and the relationship between the two systems especially during sleep (see McKenna et al 2007 for explanation and McKenna 1986); nor is the infant's thermo - regulatory system developed as the infant is unable to shiver, for example, to keep its own body warm.

Not exact matches

I have ignored reasons that might justify lower discount rates or higher GDP adjustments for China mainly because the purpose of this essay is to explain why the U.S. multiple is so much higher than China's, and of course these reasons exist, but I think whatever the correct ratio should be, there is no question that advanced economies always justify higher multiples than developing economies because they tend to be economically more diversified and politically more stable, and they usually have institutions, including clearer legal and regulatory frameworks, more sophisticated capital allocation processes, less rigid financial systems, and smaller state sectors (which make smooth adjustment, one of the most valuable and undervalued components of long - term growth, more likely).

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Organic 2.0 started in the 1970s when the writings and agricultural systems developed by our pioneers were codified into standards and then later into legally - mandated regulatory systems.

Although robust to an extent, these antiquated systems are being replaced more regularly with more technologically advanced packaging systems being developed to meet the demand and regulatory requirements that pharmaceutical companies and the supply chain service providers need to adhere to.

>> Contrast showers, spas, saunas, and cold baths are NOT recommended for prepubescent children as their thermodynamic regulatory systems are not fully developed.

We subsequently develop a model to explain how this regulatory system might utilise the subjective rating of perceived exertion (RPE) as a means of integrating afferent information and a variety of other cues in order to achieve these objectives during exercise.

Without adult presence, baby's self - regulatory systems may not be developed properly and can be undermined.

That path, according to a briefing book released in conjunction with Cuomo's budget, includes a directive to state regulators to work with NYISO to «develop a regulatory framework that will ensure system reliability while facilitating repowering to cleaner fuel or closure.»

To identify the genes, Dr. Papapanou partnered with CUMC investigators in Systems Biology who had previously developed algorithms to identify regulatory genes that fuel cancer growth.

In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.

Malinski's team has developed unique methods and systems of measurements using nanosensors, which are about 1,000 times smaller in diameter than a human hair, to track the impacts of Vitamin D3 on single endothelial cells, a vital regulatory component of the cardiovascular system.

Indeed, long - term partners may develop a shared self - regulatory system, relying on one another for support with mustering the discipline needed to face life's challenges.

The results of her project will help scientists develop novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other cancer stem cells, with the goal of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant cancer cells.

Invivoscribe has long embraced the value of quality systems and develops all products, including bioinformatics software, compliant with ISO 13485 design control, making them eligible to be brought through regulatory process to authorities worldwide.

As a global leader, Invivoscribe has long embraced the value of quality systems and develops all IVD products, including bioinformatics software in compliance with ISO 13485 design controls, making them eligible to be submitted for registration to worldwide regulatory authorities.

«More developing countries are likely to approve the technology as it's now possible to design regulatory systems that are rigorous without being onerous given their limited resources.

The data generated and the methods and tools developed within the project will also lead to a better understanding of the complex networks of genes and gene regulatory systems behind colorectal cancer.

While there, he worked with Monsanto product management, marketing, sales, regulatory and technology organizations to develop and support the launch of Roundup Ready 2 Xtend soybeans, emerging traits and technology to be utilized within the soybean agronomic system.

The regulatory system of these cells consists basically of proteins called transcription factors that control the activity of many genes — which in turn comprise the molecular machinery that instructs cells to develop into their mature, functioning state.

This reflects growing interest in the extent to which excessive activation of stress response systems can lead to disruptions in developing brain architecture that create barriers to learning, as well as impairments in other maturing organs and metabolic regulatory functions that lead to lifelong problems in health.

Furthermore, the regulatory body was moving towards a competency - based system of qualification, and it directed the LPP to consider ways to develop and assess candidate skills in the areas of professionalism and ethics; research; analysis; oral and written communications; client management; and practice management.

The Task Force also recommends, correspondingly: (a) that the Section of Legal Education, in collaboration with state regulators, develop standards for accrediting these educational programs or else expressly defer to other bodies to do so; and (b) that state authorities regulating the practice of law develop licensing or other regulatory systems for the delivery of limited legal services, which assure quality but do not limit access or unduly raise the price of services.

«Assuming that tZERO is able to develop a token trading system, numerous regulatory authorities, including FINRA and the SEC, would need to permit the trading system to become operational,» according to the filing.

«We should develop such a regulatory system on the basis of international experience that will make possible to make relations in this sphere systemic,» Putin said this week, according to CoinDesk.

About Libra Libra has spent the past three years fulfilling a critical role in the emerging landscape of blockchain technology, distributed ledger systems, and smart contracts developing software that works with a variety of protocols to deliver continuous information for audit, tax, risk, and regulatory use.

Develop, implement, and maintain quality systems procedures in compliance with regulatory requirements

Handle tasks of developing, designing, evaluating and modifying systems consistent with customer and regulatory requirements

• Developed and implemented efficient regulatory filing systems for quick retrieval of clinical trials documentation.

We do this by operating as a true backup to your team — employing the right experts as needed from our roster of over 2,500 clinical, regulatory and operational experts, paired with proprietary systems and best - practice business processes that we have developed over the last 40 years.

Successfully track more than 300 regulatory permits with developed cost containment management system.

Web Marketing and Analytics Consulting — Selected Duties and Responsibilities Lead through example with consistent work ethic, attitude, and professionalism, while developing marketing strategies through strategic target audience assessment and analysis Collaborate in all phases of strategic project planning and automation with senior - level management, including dashboard development, tracking code implementation, campaign execution, and report scheduling Provide guidance and leadership with respect to marketing campaign strategy development, benchmarking, implementation, post-execution analysis, and process optimization Measure the success of website and online marketing initiatives using data and related key metrics and evaluating the digital marketing maturity level, ensuring highest competitive abilities versus industry competitors Validate all data capturing processes and report populations with respective web analytics tools, ensuring the quality and integrity of all data within system as well as all generated reports Utilize experience in BFS, consumer goods, high - tech products / services, media, and digital marketing tools, along with related talent among team with focused collaboration and the promotion of a performance - based environment leveraging individual talents for group benefit Perform A / B and multivariate testing as well as behavior and outcome metrics analyses, reporting results in a clear, accurate, and meaningful manner to clients and management Address key client queries and resolve them in an expedited manner, promoting sustained revenue growth through client retention and relationship development Meet and exceed all marketing targets while tracking progress versus established internal and external industry benchmarks, focusing on both revenue generation as well as cost control Maintain a strong working knowledge of the product and respective marketplace, including pricing and regulatory trends, client requirements, competitor strategies, and product growth Act as a liaison between clients, vendors, sales and support staff, and executive management to facilitate information flow and drive operational efficiency

Excel Logistics (Memphis, TN) 7/2004 — 1/2006 Business Analyst • Analyzed business problems, determined cause and nature, and provided innovative solutions • Oversaw implementation of system and process solutions ensuring effective and timely resolution • Identified WMS system modifications, prepared development cost estimates, and determined timeline • Prepared acceptance test plans for WMS systems and assisted in installation and operation • Met internal and external compliance requirements including GxP and SOX for WMS systems • Approved the documentation of key deliverables including plans, protocols, reports, and change controls to ensure contents met business and regulatory requirements • Developed and managed requirement process flows • Reviewed audit reports and responded to findings

Compelling challenges include (1) the need for more extensive training for all health professionals on the adverse effects of excessive stress on the developing brain, as well as on the cardiovascular, immune, and metabolic regulatory systems (the technical report23 is a start); (2) the significant constraints on existing, office - based approaches to fully address the new morbidities effectively; (3) the relatively limited availability of evidence - based strategies, within the medical home and across the full array of existing early childhood service systems, that have been shown to reduce sources of toxic stress in the lives of young children or mitigate their adverse consequences35; and (4) the financial difficulties associated with the incorporation of evidence - based developmental strategies into the pediatric medical home.

The biology of early childhood adversity reveals the important role of toxic stress in disrupting developing brain architecture and adversely affecting the concurrent development of other organ systems and regulatory functions.

This term refers to a special class of self - regulatory processes that develop with the maturation of attentional mechanisms, particularly the anterior attention system.16 Although it is believed that effortful control begins to emerge at the end of the first year of life, its development continues at least through the preschool years, and again, is a likely candidate process in the development of childhood psychopathology.

Participants will develop an elementary understanding of the use of relational attunement as a regulatory influence that supports and stabilizes the arousal and sensory processing systems.

All states must develop a system of early childhood care and education with appropriate regulatory, governance, finance, & accountability mechanisms so that: