Sentences with phrase «reinforce earlier gene»
These genetic discoveries reinforce earlier gene studies implicating abnormal inflammation and fat metabolism in the disease.
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Katherine High, Spark's president and chief scientific officer, expressed her enthusiasm for the early clinical data related to SPK - 8011: «The encouraging start of our SPK - 8011 clinical trial reinforces the strength of our gene therapy platform, delivers human proof - of - concept in a second liver - mediated disease — a significant achievement in the gene therapy field — and positions us well to potentially transform the current treatment approach for this life - altering disease with a one - time intervention.»
The special attributes of the ancestral versions of these enzyme superfamlies, and the self - reinforcing feedback system they would have formed with the first genes and proteins, would have kick - started early biology and driven the first life forms toward greater diversity and complexity, the researchers said.
«These early results in infants reinforce hope that gene therapy will prove to be safe and effective at restoring immune function early in life,» said Brian Sorrentino, M.D., a member of the St. Jude Department of Hematology, who leads this study with Mamcarz.