One is about understanding how the function of the brain circuitry is altered by different movement -
related disease processes, such as stroke and Parkinson's disease.
While translational research has traditionally moved basic immunology knowledge forward into clinical application, varying clinical presentations of human immune -
related disease processes, as well as variability in therapeutic outcomes, have provided opportunities for discovery of novel mechanistic hypotheses directly from patients.
Not exact matches
For those with a less diverse microbiome, the diet had a positive impact on their metabolic health — meaning a lowered their risk for type 2 diabetes and other
diseases related to how the body
processes food.
Higher levels of obesity, diabetes, cardiovascular
disease and other health -
related issues are found in food deserts because residents are buying a lot of
processed foods from convenience or liquor stores.
An expert panel convened by the Institute of Medicine clarified the cognitive aging
process by making a distinction from Alzheimer
disease and
related dementias, and provided recommendations to enhance cognitive health in older adults.
«Inactivity may diminish life expectancy not only by predisposing to aging -
related diseases but also because it may influence the aging
process itself.»
Researchers only discovered this
process in the late 1990s, but they've already begun dozens of clinical trials to gauge whether infusing patients with these small RNAs works against a range of
diseases, from lung infections to liver cancer to age -
related macular degeneration, a sight - stealing condition that mainly affects people over the age of 50.
Developing a better understanding of the large - scale mechanical changes that occur over longer distances, specifically the
process by which the extracellular matrix is pulled into compact, highly - aligned «bridges,» could eventually form the basis of treatments for
related diseases.
Now, however, Thangamani Muthukumar, MD (Weill Medical College of Cornell University) and his colleagues have developed a urine test that measures the levels of several messenger RNAs (mRNAs) that are directly
related to the
disease processes that cause kidney dysfunction.
Common age - and diabetes -
related retinal
diseases, such as wet macular degeneration, also result in part from VEGF - driven
processes, so ophthalmologists soon began to use Avastin «off - label» to treat these conditions.
As noted in the study by Crimmins and lead author Morgan E. Levine, assistant professor at the Yale Center for Research on Aging: «A deceleration of the human aging
process, whether accomplished through environment or biomedical intervention, would push the timing of aging -
related disease and disability incidence closer to the end of life.»
Together with research into other immune -
related genes in
diseases such as Alzheimer's, the idea that immune
processes are involved in some psychiatric phenotypes is looking ever more solid.
«Influencing the aging
process itself may be an alternative approach with the potential to yield broadly effective therapeutics against age -
related diseases.»
According to the Center for
Disease Control, the most common sources of contamination in the US water system are
related to local land uses and manufacturing
processes.
In addition to providing a platform for studying the
processes that regulate platelet production and
related diseases, the researchers hope the platelets produced can be used as a source of growth factors for wound healing in regenerative medicine, including healing of ulcers and burns, and stimulation of bone tissue regeneration in dentistry and maxillofacial plastic surgery.
And some research has hinted that biomarkers
related to one
disease can spur molecular
processes leading to others.
The technique, carried out in living human cells and fruit flies, should help reveal how irregularities in protein synthesis contribute to developmental abnormalities and human
disease processes including those involved in Alzheimer's
disease and other memory -
related disorders.
LA JOLLA — A study tying the aging
process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age -
related diseases such as cancer, diabetes and Alzheimer's
disease, as detailed April 30, 2015, in Science.
This will allow
disease related defects to be identified, and new targets researched to understand this vital biological
process.
Collectively, these will advance the understanding of the role ChrX plays in the etiology of age -
related diseases, which will also have an important positive impact on our understanding of sex differences in aging
processes.
It is based on the scientific understanding and high - throughput analyses of human immune responses to
disease -
related proteins in selected populations including elderly with the capability to stay healthy during the aging
process.
To speed the identification of genes
related to human
diseases and to aid in the understanding of basic biological
processes, the Howard Hughes Medical Institute (HHMI) and the Washington University...
In particular his work is focused on how this receptor may affect cognitive
processes, and how this
relates to Alzheimer's
disease.
Oisín Biotechnologies» ground - breaking research and technology is demonstrating that the solution to mitigating the effects of age -
related diseases is to address the damage created by the aging
process itself.
It may be that, most likely, 5 of the therapies will impact health to nullify many
disease but will not change the «aging»
process (the one that is disconnected from telomeres but
related with epigenetics) and 2 last therapies will be of intrinsic aging, of which one could end up not doing anything but remain a mitochondrial improvement manifesting as removal of mitopathies (such as MELAS) but would not alter the course of aging (such as the seperate epigenetic aging going on).
New Protein Survey Upends Understanding of Cell Death
Process - Results from the Cravatt lab reveal numerous potential new drug targets for
related diseases.
Believed to be one of the primary actors in the aging
process, free radicals are also implicated in numerous age -
related diseases, including cancer, heart
disease, stroke, and many neurological disorders.
In general, the growing participation of CNAG - CRG in rare
disease research projects is clear in terms of samples sequenced; while during the period 2014/2015 the total number of
processed samples
related to rare
diseases was of 523 in the period 2016/2017 the number of these samples increased to more than 1600.
In ALS and
related degenerative
diseases, the
process of assembling and clearing RNA granules is impaired.
«The results go a long way to explaining the
process that links a variety of neurodegenerative
diseases, including ALS, frontotemporal dementia and
related diseases of the brain, muscle and bone known as multisystem proteinopathies,» said the study's co-corresponding author, J. Paul Taylor, M.D., Ph.D., a member of the St. Jude Department of Developmental Neurobiology.
The cells that are most vulnerable to this
process are muscle -
related sensory neurons whose degeneration leads to the first symptoms of the
disease.
These fibrotic
processes, nowadays more frequently detected, may be
related to defects in the repair
process and / or to an increased incidence of autoimmune
diseases due to ageing.
LA JOLLA — A study tying the aging
process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age -
related diseases such as cancer,...
Whatever the goal of the researcher, the Director of the Core, Dr. Simon Melov, has a broad and deep experience in the investigation of basic
processes of aging and age -
related disease in multiple organisms and tissues.
National Institute on Aging (NIA)-- Est. 1974 NIA leads a national program of research on the biomedical, social, and behavioral aspects of the aging
process; the prevention of age -
related diseases and disabilities; and the promotion of a better quality of life for all older Americans.
By studying the regenerative capabilities of diverse animals, we are making important discoveries about age -
related diseases, including heart
disease, Alzheimer's and Parkinson's — even the
process of aging itself.
In fact, because many mechanisms of aging are broadly conserved across animals, including Drosophila, research on the signaling networks that regulate this
process could eventually have profound impacts on the treatment of age -
related diseases like Alzheimer's.
With up to 20 research mentors participating, students have the opportunity to explore research involving the aging
process and aging -
related diseases.
So we should reconsider our thought
process on what underlies this devastating
disease, especially as it
relates to the role of beta - amyloid.
To underscore the significance of chronic inflammation, scientists have identified it's an underlying
process in all age -
related diseases including type 2 diabetes, atherosclerosis, arthritis, and neurodegenerative
diseases like Alzheimer's.
The most significant outcome of the research was that cortical abnormalities which take place in individuals with migraine are a consequence of the balance between an intrinsic predisposition, as indicated by modification of cortical surface area, and
processes related to
disease, as indicated by abnormalities of cortical thickness.
Ageing is just a natural
process that might show up at any age and which is reflected not only by the modifications in our body appearance, but more importantly by the internal signs proving a gradual deterioration in our inner body ability to ensure an optimal metabolism and physiology, to keep a strong immune system and consequently to prevent and fight the chain of degenerative chronic
diseases, also called age -
related diseases.
Dr Rashid Buttar, medical director of a clinic specializing in treating cancer, heart
disease and other chronic conditions, states «I can now very comfortably state to you that in my opinion, based on the evidence, every single chronic insidious
disease process is
related to one word: toxicity.
This decline impairs mitochondrial function, playing a crucial role in the development of metabolic dysfunction, age -
related diseases and that this decline is both a consequence of and contributor to the aging
process.
Research studies are showing that IF can counteract
disease processes as it
relates to age
related diseases.
Eliminating sugar and
processed foods and adding nutrient dense foods and supplements to your arsenal of weapons against
disease, and also a thorough treatment of detox activities (colon — which is directly
related to your sinuses, intestinal, kidney, liver / gallbladder, lymphatic, blood, and skin) will get you back on track.
But, hormonal imbalances usually occur due to work -
related issues; eating too many
processed foods, EMF pollution plus poor sleeping habits — which lead to chronic inflammation, weight gain and
disease.
Refined
processed carbohydrates are the major cause of weight gain, obesity, specific skin conditions, and many diet
related diseases including heart
disease, hypertension, insulin resistance, type 2 diabetes, some cancers, and obesity.
Over-consumption of refined,
processed carbohydrates is a major cause of weight gain, insulin resistance, metabolic syndrome X, obesity, type 2 diabetes, heart
disease, high blood pressure, food cravings, and many diet
related diseases.
Traditionally, cognitive behavioral therapists have helped people
process unresolved trauma, but more recently psychiatrists, psychologists, clinical social workers — many working with US military veterans — acknowledge that embodiment practices such as yoga enriched with mindfulness practices can have more impact in alleviating the symptoms that lead to both reactive behaviors and stress
related disease.