Sentences with phrase «related gene amh»

In human populations, genome - wide association studies have revealed associations between variants of the circadian clock — related gene Mntr1b, which encodes melatonin receptor 1B, fasting glucose concentrations, and the risk of type 2 diabetes (12 — 14).
However, the good news is that according to the 2011 study even moderate physical activity such as walking is able to reduce the negative influence of this obesity - related gene variation by more than 25 %!
The transition actually shifts metabolic related gene expression, increasing fat oxidation pathways and decreasing fat storage pathways.
Together these studies indicate the possibility that prenatal exposure to SSRIs might directly affect the developing brain, perhaps selectively in fetuses having serotonin related gene abnormalities.
We found out when we examined genes that quite often we could find evidence that one gene had given the path of its sequence to another related gene, so it was as if there were two genes and one said, «I'm not going through, the New York business,» and the other one said the slightly different message, and yet they exchanged information.
47/3: 30 Evolution and structural diversity of the complement factor H related gene cluster.
Because all the study subjects had been middle ranking in their original groups, we can infer that it was the new dominance ranks they adopted that explained rank - related gene expression.
The Arabidopsis ssi1 Mutation Restores Pathogenesis - Related Gene Expression in npr1 Plants and Renders Defensin Gene Expression Salicylic Acid Dependent
A Harpin Binding Site in Tobacco Plasma Membranes Mediates Activation of the Pathogenesis - Related Gene HIN1 Independent of Extracellular Calcium but Dependent on Mitogen - Activated Protein Kinase Activity
The Caenorhabditis elegans unc - 103 gene encodes a potassium channel whose sequence is most similar to the ether - a-go-go related gene (erg) type of K + channels.
But CPEBs are not limited to the transcriptionally silent germline; they are also expressed, in various combinations, in somatic cells, yet their role in regulation of mitosis - related gene expression is largely unknown.
The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.
We use three sources of information to update the homology - based immune catalog in Nasonia: a previously published catalog of antimicrobial peptides [35], homology to characterized Dipteran immune proteins based on reciprocal best blastp hits to D. melanogaster, and profile hidden Markov models (HMMs) of known immune - related gene families derived from ImmunoDB [11](see methods for details).
The effect of colonization of cdrA (cell division - related gene)- disrupted Helicobacter pylori to host response in human stomach.
It's widely known that many East Asians have a mutation in a related gene that renders this pathway nonfunctional.
To study the effects of LRO - related gene mutations, Dr. Huizing is performing fluorescent protein expression studies using patients» cells in order to examine defective intracellular trafficking.
We have established stably transfected HEK 293 cell lines expressing high levels of functional human ether - a go - go - related gene (HERG) channels.
They found striking recurrence of lysine - 27 mutations in H3F3A or the closely related gene HIST1H3B (which encodes H3.1) in 78 % of gliomas and 22 % of non-brainstem glioblastomas.
Intracellular retention of the NKG2D ligand MHC class I chain - related gene A in human melanomas confers immune privilege and prevents NK cell - mediated cytotoxicity.
Finding MODY3 led to the rapid discovery of MODY1, a functionally related gene known as HNF -4-alpha, which had been mapped to the MODY1 - region of chromosome 20 by Markus Stoffel, MD, Rockefeller University, a collaborator in the search for MODY1 since 1991.
Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin - related gene expression that is not reversed by citalopram.
Development of a gene expression assay in non-human primates: We will develop a novel sensitive assay for the characterisation of vaccination - related gene expression profiles in NHPs, using an approach that is fully harmonised with the systems biology platform.
ISIS - SMNRx is designed to treat all types of childhood SMA by altering the splicing of a closely related gene (SMN2) that leads to the increased production of fully functional SMN protein.
ISIS - SMNRx is designed to alter the splicing of a closely related gene (SMN2) to increase production of fully functional SMN protein.
In addition, researchers found that the gene families related to whale's body hair and sensory receptors were contracted, such as Keratin - related gene families associated with hair formation, several Hox genes that play an important role in the body plan and embryonic development.
As well as Zika virus, the team has also used SHERLOCK to detect antibiotic resistance genes in Klebsiella pneumoniae bacteria, and health - related gene variants in human saliva (Science, DOI: 10.1126 / science.aam9321).
As well as Zika virus, the team has also used SHERLOCK to detect antibiotic resistance genes in Klebsiella pneumoniae bacteria, and health - related gene variants in human saliva.
Having more schizophrenia risk - related gene variants was also associated with a greater decline in lifelong cognitive ability.
HDNetDB allows users to obtain, visualise and prioritise molecular interaction networks using Huntington's disease - related gene expression and other types of data obtained from human samples and other sources.
Although BRAF gene fusions were well known to be involved in PLGGs, the study team found important differences in a related gene, CRAF, in which mutations can also lead to this type of glioma.
The other team, led by medical psychologist Julie Williams of Cardiff University in Wales, noted the same CLU gene and identified another Alzheimer's - related gene, PICALM.
Comparing the two sets of genes, the team discovered several immune - related gene variants that were rare among the living.
Each obesity - related gene affects a different aspect of weight control.
This study found that when cacophony and its related gene straitjacket are mutated, they cause similar degenerative phenotypes in the mutant neurons as autophagy mutants.
To his surprise, Lo found four different MLV - related gene sequences in 32 of the 37 patient samples.
«This is an exciting study of a very rare bone disorder that not only identified the responsible mutation in half of the patients, but uncovered fundamental information about the role of a cancer - related gene in the metabolic pathways of normal bone,» said study co-senior author Joan Marini, Ph.D., M.D., of NICHD.
In the dominant deafness model, gene therapy with a related gene, TMC2, was successful at the cellular and brain level, and partially successful at restoring actual hearing in the startle test.
SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.
Y. Ning et al., Genetic analysis of indefinite division of human cells: Evidence for a cell senescence - related gene (s) on human chromosome 4.
A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.
Habit then uses blood samples and DNA from a cheek swab to glean details on glucose levels and obesity - related genes, among other factors that could affect metabolism.
The company's technologies provide customers with powerful new ways to examine disease - related genes.
«We wanted to find out if obesity - related genes and activity level have an interactive effect on obesity risk — if there is a «double whammy» effect of being both at genetic risk and physically inactive, beyond the additive effect of these factors,» said Dr. Wood.
Since then, Pereira - Smith's team has moved into using genetic techniques in mice to study whether and how senescence is regulated by MORF4 and related genes.
But when the researchers compared the genomes of opossums and humans, they found a surprising number of similar immune - related genes, meaning it's useful for just the opposite of the expected reason: The gray short - tailed opossum is a nice model for immunology research.
Our study opens the window for the possibility of linking age - related genes as therapeutics for the future.»
For them, the discovery of how an individual becomes gay is likely to shed light on how sexuality - related genes build brains, how people of any persuasion are attracted to each other, and perhaps even how homosexuality evolved.
Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease - related genes.
However, other institutions and companies have continued to file patent applications on ESTs and related genes; at present there are applications covering more than 1 million ESTs on file in the PTO.
«Taken together, these results support the hypothesis that multiple myeloma cells express bone - related genes in a Runx2 - dependent fashion that mimics bone marrow resident cells and likely contributes to tumor survival and growth in the bone microenvironment,» Yang and colleagues wrote in the paper.
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