Sentences with phrase «related gene sequences»

To his surprise, Lo found four different MLV - related gene sequences in 32 of the 37 patient samples.

Not exact matches

The scientists compared the genetic sequence of five related strains of the species, looking for orphan genes and examining the life cycles of the various genes in the fly genome.

Fiers investigated the nucleotide sequence of the hemagglutinin gene of this duck virus and found that it was indeed very closely related to the strain that started the 1968 Hong Kong outbreak.

They downloaded sequences of more than 700 genes from organisms ranging from fruit flies to humans and compared genes from closely related species.

They processed data relating to genetics, including DNA sequences, and to gene expression, as well as epigenetic features — chemical reactions that influence genome functioning and hence phenotype by activating and deactivating genes.

Before the consortium came together, he had participated in sequencing the genomes of two vocal learners, a songbird and a parrot, but he knew he couldn't do all of the additional sequencing and analysis work that would be required to identify genes related to vocal learning — not by himself, at least — so he teamed up with Genome 10K, a project aiming to collect genomes for 10,000 vertebrate species.

The researchers then compared the expression of all genes in six parts of the brain of the two bird species using state - of - the - art molecular techniques, including next - generation sequencing — the first time these tools have been used to find brain properties related to innovation and problem - solving in wild birds.

They also ruled out other possibilities, including the gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead gene, or closely related DNA sequences providing a template for repairs.

In Class II engagement, Sox9 binds to multiple active enhancer elements through sub-optimal, low - affinity Sox dimeric motifs (DNA sequences), resulting in a high level of transcription of cartilage - related genes.

The researchers from Queen Mary University of London sequenced the HAS2 gene in thirteen similar or related mammals, combining the data with DNA sequences extracted from 57 published genomes representing all the major mammal groups.

With the state - of - the - art DNA sequencing technology used in this study, they will be able to pinpoint the exact mistake in each patient's SS - related genes.

The UW team discovered that some codons, which they called duons, can have two meanings, one related to protein sequence, and one related to gene control.

Both studies relied on a popular lab organism known as C. elegans, a nearly microscopic nematode that is fast growing, translucent and has a sequenced genome showing that nearly half its genes are closely related to corresponding human genes.

The sequence contains genes related to body fat distribution, important for surviving the cold.

Michael Metzker, at the time a graduate student in the laboratory of Richard Gibbs at Baylor College of Medicine in Houston, compared the gene sequences of the strains to see how closely related they were, using a technique called phylogenetic analysis.

Now, a sequence of 346 base pairs of one of the virus's genes has shown that the two outbreaks aren't directly related.

Ruiz - Trillo and his team sequenced the Capsaspora genome in an earlier project and discovered that the amoeba contained many genes that, in animals, are related to multicellular functions.

By comparing worm and human sequence, scientists can identify the related genes, and then use the worm to examine their function.

Wellems's team was studying chromosome 7 of P. falciparum in search of a gene that renders malaria resistant to the drug chloroquine, when they came across a cluster of five related genetic sequences.

Other animals possess their own versions of FOXP2, suggesting that it might be possible to determine which evolutionary changes to the gene's DNA sequence are most closely related to our ability to talk.

Advancements in such genome sequencing have enabled the scientists to make comparisons of gene similarity between closely related species — wheat and barley, for example — and more distantly related species such as wheat and maize.

When she finished her bachelor's degree, Zeggini went to the Arthritis Research Campaign Epidemiology Unit at the University of Manchester to do a Ph.D. on the sequencing of genes related to juvenile oligoarthritis, a complex autoimmune disease.

But after analyzing the Hofstenia transcriptome, the team determined that the three - banded panther worm and planarians are only very distantly related, a view that had been proposed based on analyses with sequences from a small number of genes.

(C) Analysis of the variable gene sequences from plasmablasts of the four pandemic H1N1 - infected patients indicated that ∼ 16.5 % of the pandemic H1N1 - induced plasmablasts were clonally related (shared identical VH and JH genes and CDR3 junctions).

«Their duplicated hybrid genome architectures provide these nematodes with multi-copy genes showing diverged sequence and expression patterns where their sexual relatives have very closely related alleles,» says Danchin.

Comparisons between the nucleotide makeup, or sequence, of particular genes allows scientists to see how closely they are related, and thus, group the organisms accordingly.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus Erythematosis by utilizing deCODE's expertise in gene discovery.

In contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the test.

For instance, the mouse sequence revealed that mice have two genes related to the gene involved in Lowe's syndrome, an inherited metabolic disorder in humans.

(A) Phylogenetic analysis of D11 - and Dwf4 - related genes based on coding sequence.

They also chose a gene target that might itself be problematic, given that it is part of a closely linked family of globin genes with highly related sequences, making it hard to target one without affecting the others.

2610511A05Rik; 2610511A05Rik; 9030605P22Rik; 9030605P22Rik; Ahl4; BB234005; Cis; Cis; RIKEN cDNA 2610511A05 gene; RIKEN cDNA 9030605P22 gene; age related hearing loss 4; ahl4; expressed sequence BB234005

Lower sequence coverage (survey sequencing) of related species can yield a wealth of information about gene content and putative regulatory elements.

To provide access to the gene sequences of the tomato and related species, Boyce Thompson Institute scientist Lukas Mueller and his team have created an interactive website (www.solgenomics.net).

S2), whereas gene sampling among species with only one or a few sequences is focused on a few mitochondrial genes so that gene overlap is generally high among congeneric species and closely related genera.

Thus, despite the rapid increase in available genome sequence across insects, our functional knowledge of the diversity of immune - related genes has not kept pace.

The Caenorhabditis elegans unc - 103 gene encodes a potassium channel whose sequence is most similar to the ether - a-go-go related gene (erg) type of K + channels.

The study is considered proof - of - principle that gene sequencing to identify cancer - related alterations may be a helpful tool in detecting cancer DNA directly in the blood and potentially other body fluids.

Here, we employed cDNA amplicon sequencing using a long - read portable sequencer, MinION, to characterize various types of mutations in cancer - related genes, namely, EGFR, KRAS, NRAS and NF1.

Recent evidence has connected MI risk with coding - sequence mutations at two genes functionally related to APOA5, namely lipoprotein lipase and apolipoprotein C - III (refs 18, 19).

We found out when we examined genes that quite often we could find evidence that one gene had given the path of its sequence to another related gene, so it was as if there were two genes and one said, «I'm not going through, the New York business,» and the other one said the slightly different message, and yet they exchanged information.