Sentences with phrase «related gene sets»

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

Not exact matches

Two newly discovered members of the mimivirus family, both called tupanviruses and both with tails, have the most complete set of genes related to assembling proteins yet seen in viruses (SN Online: 2/27/18).

To test this hypothesis, an international team led by evolutionary biologist Philipp Khaitovich of the Shanghai Institutes for Biological Sciences in China and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, set out to see how many brain - related genes implicated in schizophrenia underwent positive natural selection since humans and chimpanzees diverged from a common ancestor between 5 million and 7 million years ago.

The new study examined the entire set of active genes, or the transcriptome, of 24 conifers and other seed plants and three distantly related plants.

With the data provided by the FLI researchers, scientists around the world may now set targeted mutations to investigate the relevance of single genes for aging, in order to better understand regulating mechanisms and, eventually, develop new approaches for therapy or prevention of aging - related diseases.

This network discourages violence, Sheehy speculates, because peaceable interactions may help related males set up their own territories and attract mates, thereby increasing the likelihood that shared family genes get passed on.

Importantly, the team identified a set of psoriasis - related genes in keratinocytes that are regulated by IL - 17A.

«The lines drawn between different disorders are not related to the genes that predispose to the disorders,» Cantor notes, explaining that two children can present very similar behavioral patterns but have vastly different sets of copy number variations — and vice versa.

Comparing the two sets of genes, the team discovered several immune - related gene variants that were rare among the living.

The research team also tried to find a predictive set of genes in people aged 60 and above — a group that includes those more likely to develop serious flu - related complications, such as pneumonia — but failed.

Researchers observed that the set of genes involved in memory consolidation coincided with the genes regulating Crtc1, a protein which also controls genes related to the metabolism of glucose and to cancer.

Researchers from North Carolina State University have developed a technique that co-opts an immune system already present in bacteria and archaea to turn off specific genes or sets of genes — creating a powerful tool for future research on genetics and related fields.

«And this approach could be used in conjunction with high - throughput screening techniques to identify gene sets associated with problems such as multidrug resistance or benefits, like those related to probiotics.»

GOMiner — To provide additional statistical stringency to the identification of potential targets, we then analyzed the data sets generated by the SAM - RS analysis of the microarray data for hypoxia - associated coregulation of multiple, functionally related genes.

Gene Set Enrichment Analysis (GSEA) is a microarray data - mining technique used to determine whether there is coordinated differential expression or «enrichment» in a set of functionally related genes when comparing control and experimental samples [3Set Enrichment Analysis (GSEA) is a microarray data - mining technique used to determine whether there is coordinated differential expression or «enrichment» in a set of functionally related genes when comparing control and experimental samples [3set of functionally related genes when comparing control and experimental samples [35].

The UK patents relate to the CRISPR - Cas9 gene editing systems involving single - guide RNA in both non-cellular and cellular settings (UK Patent No. 2518764) and chimeric CRISPR - Cas9 systems in which the Cas9 protein is modified to provide alternative DNA - modulating activities (UK Patent No. 2537000).

Also, genes related to «protein folding» (GO: 0006457; P = 7.84 e − 04) and those responding to osmotic and starvation stress were enriched, suggesting that nutrient remobilization and stress pathways are activated during the loss of meristem activity and development of bristles (Supplemental Data Sets 4 and 5).

«What makes it particularly interesting is that the region we can show is associated with protection happens to be right up against a set of genes we know are related to how malaria invades the red blood cell,» study author Dominic Kwiatkowski of the Wellcome Trust Sanger Institute and the Wellcome Trust Centre for Human Genetics told The Post.

Microarray analysis revealed temperature - dependent expression of distinct sets of genes, as well as 700 A. fumigatus genes not present or significantly diverged in the closely related sexual species Neosartorya fischeri, many of which may have roles in the pathogenicity phenotype.

Each olfactory nerve cell expresses just one of these olfactory genes to produce a receptor that recognizes a related set of odors.

Here, we report the infection - induced transcriptome of the non-eusocial parasitic wasp Nasonia vitripennis, combined with a new homology - based characterization of immune - related genes in the Official Gene Set V2.0 (OGSv2: http://arthropods.eugenes.org/EvidentialGene/nasonia/).

Notably, however, the vast majority of induced genes are not recognized as immune - related by homology alone: just 12 % are in the homology - based immune set.

Here we screened the core set of genes related to histone methylation (KMT2D, SETD2, KMT2A, KDM6A) and acetylation (EP300, CREBBP) and identified 59 somatic mutations in 45 of 125 (36.0 %) patients with peripheral T - cell lymphomas, not otherwise specified.

«Clustering, the predominant current strategy, only tells you which sets of genes have related expression profiles and what those profiles look like in a general sense,» she said.

Where possible, value is added by focusing on sets of genes that serve related biological functions, and offering insight into the mechanism by which phenotypes arise.

Having evolved in a region with less climate variability over both the years and the millennia, tropical species may harbor a less diverse set of genes related to heat tolerance and similar traits.