Sentences with phrase «related gene variants»

As well as Zika virus, the team has also used SHERLOCK to detect antibiotic resistance genes in Klebsiella pneumoniae bacteria, and health - related gene variants in human saliva (Science, DOI: 10.1126 / science.aam9321).

As well as Zika virus, the team has also used SHERLOCK to detect antibiotic resistance genes in Klebsiella pneumoniae bacteria, and health - related gene variants in human saliva.

Having more schizophrenia risk - related gene variants was also associated with a greater decline in lifelong cognitive ability.

Comparing the two sets of genes, the team discovered several immune - related gene variants that were rare among the living.

Not exact matches

To link, at a molecular level, a gene variant with biochemical changes and clinical symptoms related to a heritable psychiatric disorder, as in this present study, is therefore something of a breakthrough.

«In the current study, we analyzed dozens of variants of those genes and other genes frequently associated with obesity risk and saw that, while total fat intake was related to higher BMI, people who were genetically predisposed to obesity and ate the most saturated fat had the highest BMIs.»

«Our research suggests that such variants may have piggybacked onto positively selected regions, which were also enriched in disease - related genes,» Lohmueller said.

Spalax naturally have a variant in the p53 gene (a transcription factor and known tumor suppressor), which is identical to a cancer - related mutation in humans, Band said.

First, autism may not be rigidly determined but instead may be related to common gene variants, called polymorphisms, that may be derailed by environmental triggers.

«GECCO aims to continue to discover additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle risk factors, including biomarkers as well as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer risk.

«In our research, we show that when people taste alcohol in the laboratory, the amount of bitterness they experience differs, and these differences are related to which variant of a bitter receptor gene the individual has.»

Candidate gene and genome - wide association studies have identified variants associated with HBV - related disease progression or hepatocellular carcinoma in various populations [46][52].

The lovely violin plots at right show the mean GERP scores (a measure of conservation) for included versus excluded variants in the newborn screening (NBS), age - related macular degeneration (ARMD), and pharmacogenetics (PGx) genes examined.

Reykjavik, ICELAND, 12 October 2011 — deCODE genetics today announced that it has entered into a research collaboration with Pfizer Inc., the objective of which is to discover sequence variants associated with specific clinical phenotypes related to Systemic Lupus Erythematosis by utilizing deCODE's expertise in gene discovery.

In contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the test.

Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin - related gene expression that is not reversed by citalopram.

The alliance will initially focus on the development, validation and commercialization of specific diagnostic tests for variants in genes involved in three disease - related pathways:

According to Andreassen, the study's senior author, some think of schizophrenia as a «side effect» arising from advantageous variants in genes that are related to the development of human traits, such as cognitive and language skills, that may have increased risks for developing psychoses.

Potential projects include identifying common pathways that modify retinal degenerative disease from a large collection of actively maintained mouse models; determining molecular networks implicated in pathological disruption of the retinal pigment epithelium; identifying molecular pathways that regulate postnatal ocular growth; and using mouse models to assess the pathogenic role of gene variants that increase the risk of age - related macular degeneration as identified by human genome - wide association studies.

Increased autism risk was also linked to other maternal gene variants related to less efficient one - carbon metabolism, but only when the mother did not take the prenatal vitamins in the early months before and immediately after conception.

People with ABCC8 - related familial hyperinsulinism most often have two variants in the ABCC8 gene.

People with GJB2 - related DFNB1 most often have two variants in the GJB2 gene.

In human populations, genome - wide association studies have revealed associations between variants of the circadian clock — related gene Mntr1b, which encodes melatonin receptor 1B, fasting glucose concentrations, and the risk of type 2 diabetes (12 — 14).