However, the good news is that according to the 2011 study even moderate physical activity such as walking is able to reduce the negative influence of this obesity -
related gene variation by more than 25 %!
Not exact matches
Their analysis uncovered small
variations in two
genes related to the accelerated aging of the cerebellum.
«The lines drawn between different disorders are not
related to the
genes that predispose to the disorders,» Cantor notes, explaining that two children can present very similar behavioral patterns but have vastly different sets of copy number
variations — and vice versa.
Variations in two
genes could account for three - quarters of all cases of age -
related macular degeneration, a new study reports.
For this study, the team, which also included Bernard Crespi, an evolutionary biology professor at Simon Fraser University in British Columbia, and East Carolina University evolution professor Kyle Summers, focused on 76
gene variations most strongly
related to schizophrenia.
They hypothesized that the differences might be
related to
variations in two
genes, called ASPM and microcephalin, which are thought to be implicated in brain development.
Covering the entire genome, the study discovered that a common
variation in the melatonin receptor 1A (MTNR1A)
gene is linked to the job -
related exhaustion experienced by shift workers.
Mariman EC, Bouwman FG, Aller EE, van Baak MA, Wang P. Extreme obesity is associated with
variation in
genes related to the circadian rhythm of food intake and hypothalamic signaling.
The researchers in this study have pinpointed
variations in a specific
gene — MC1R — that are directly
related to how old people appear to others.
By characterizing the role of
gene mutations and copy number
variations in a number of complement associated disorders, including kidney diseases, such as HUS (Hemolytic Uremic Syndrome), DDD (Dense Deposit Disease) or AMD (Age
Related Macular Degeneration) the group has identified new disease subtypes of this severe kidney diseases.
Pierce et al. in a fascinating BMJ article state that only 7 % of human genetic
variation is due to race and very few of these
variations relate to health, skewering the thrifty
gene hypothesis along the way (Pearce, Foliaki et al. 2004).
Allelic
variation in this transporter's
gene expression, regulated by a 43 bp indel in the upstream region termed 5 - HTTLPR, was initially associated with anxiety -
related traits (23) and has since been investigated in many fields of serotonin -
related human genetics (24).
From early models, temperament has been thought to have a constitutional basis.1 Recent evidence is showing that polymorphic
variation in dopamine -
related genes is associated to individual differences in EC and attentional control.16 However, the relevance of the biological endowment for EC does not mean that this ability can not be influenced by experience.
Related to this question, recent research suggests that particular polymorphisms, often those linked to risk for pathology, make the individual more susceptible to be influenced by parenting and other experiences.24 - 26 For example, children carrying the 7 - repeat
variation of the DRD4 appear to benefit more from interventions directed to prevent behaviour problems than those carrying other
variations of the
gene.24 Nonetheless, further research is needed on how and to what extent EC skills may be influenced by the interplay between constitution and experience.
Interaction between BDNF Val66Met and dopamine transporter
gene variation influences anxiety -
related traits