Genetic manipulation of serotonin -
related genes also influenced anxiety - like behaviors in a manner similar to what has been reported earlier in mice.
Not exact matches
In addition to DOT Commissioner Trottenberg and officials,
also in attendance at today's Task Force meeting were: Luke DiPalma and Buckley Yung of the Metropolitan Transportation Authority (MTA); Anthony Iuliano of the New York City Department of Buildings; Howard Pollack of the NYC Department of Design & Construction (DDC); Deputy Inspector Thomas Conforti, Detective Kevin O'Donnell and Officer Joseph McCall of the NYPD 109th Precinct;
Gene Kelty, Charles Apelian and Marilyn Bitterman of Community Board 7; Dian Song Yu of the Downtown Flushing Business Improvement District; Ikhwan Rim, President of the Union Street Business Association; Chris Kui of Asian Americans for Equality; Michael Meyers and Howard Hsu of the F&T Group; Glen Johnson of Tishman Speyer; Rick Sondik of the Rockefeller Group; Daryl Finn of Skyview Center /
Related Management; representatives for State Senator Toby Stavisky, Assemblymember Ron Kim and Councilmember Peter Koo.
Next, the authors compared their stickleback results to previously published opsin
genes in two
related species of fish (bluefin killifish and black bream), separated from sticklebacks by millions of years, that had
also adapted to blackwater and clearwater habitats.
They are
also studying whether the nanoparticles can be used with the CRISPR / Cas9
gene - editing technique to treat genetic lesions
related to retinal degenerative diseases.
NF - kB may
also regulate a number of
genes related to immune suppression, particularly TGF - beta, IL - 10, GM - CSF, G - CSF and VEGF.
It has multiple hosts and can evolve by mutation but
also reassortment (when two closely
related strains infect the same host and exchange
gene segments, producing new strains — a process distinct from mutation, when the RNA of a virus is miscoded during replication).
«Brain
genes related to innovation revealed in birds: Glutamate brain receptors, linked with human intelligence, are
also associated with problem - solving skills in wild birds.»
«Our research suggests that such variants may have piggybacked onto positively selected regions, which were
also enriched in disease -
related genes,» Lohmueller said.
They
also ruled out other possibilities, including the
gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead
gene, or closely
related DNA sequences providing a template for repairs.
«We were surprised that the heritability of depressive symptoms in twins with very short sleep was nearly twice the heritability in twins sleeping normal amounts of time,» said principal investigator Dr. Nathaniel Watson, associate professor of neurology and co-director of the University of Washington Medicine Sleep Center in Seattle, Wash. «Both short and excessively long sleep durations appear to activate
genes related to depressive symptoms,» added Watson, who
also serves on the board of directors of the American Academy of Sleep Medicine.
They found that six of the categories included a high proportion of
genes also implicated in schizophrenia; the
genes in these six categories
relate to energy metabolism.
And 40
genes involved in these nine schizophrenia -
related pathways
also differed much more between chimps and humans than
genes associated with the other 12.
The Nature study
also adds to what is known about how
genes are transferred from one species to another when individuals from two closely
related species mate.
Fascinatingly, however, the Cambridge - Sheffield study has now shown that exactly the same
gene also influences the extremely bright and colourful patterns of Heliconius — the name given to about 40 different closely -
related species of beautiful, tropical butterflies found in South America.
For example, many of the
genes in the new networks are
related to cancer, suggesting that certain cancer treatments that target these
genes might
also be useful to treat ASD.
Greenberg's lab
also found that the disruption of long
gene expression appears to be a distinctive signature of Rett Syndrome and
related disorders.
The ascidian genome has
also acquired a number of lineage - specific innovations, including a group of
genes engaged in cellulose metabolism that are
related to those in bacteria and fungi.
«We are learning more about the influence of
genes not only underlying racing performance and disease but
also about health -
related traits such as risk of fracture,» she said.
Insofar, the results are
also relevant for humans: 85 % of the long - lived rodents»
genes are identical to human DNA, but in contrast to humans that are rather prone to illness, long - lived rodents have a very low risk to come down with age -
related diseases.
Another important pathway,
related to the p53
gene (a protector of the genome), is
also relevant when we looked at
gene expression in the skin of acne twins compared to twin controls.»
This incompletely inactivation of
genes on the X chromosome, including many immunity -
related genes, may help explain why females are predisposed to many autoimmune conditions and
also have stronger immune responses than males.
Although BRAF
gene fusions were well known to be involved in PLGGs, the study team found important differences in a
related gene, CRAF, in which mutations can
also lead to this type of glioma.
The researchers
also identified several new
genes related to anxiety behavior in flies.
The research team
also tried to find a predictive set of
genes in people aged 60 and above — a group that includes those more likely to develop serious flu -
related complications, such as pneumonia — but failed.
The 2 percent distinction
also involves an unusually large fraction of
genes related to the immune system, parasite vulnerability, and infectious diseases: Chimps are resistant to malaria, and we aren't; we handle tuberculosis better than they do.
Having more schizophrenia risk -
related gene variants was
also associated with a greater decline in lifelong cognitive ability.
As well as Zika virus, the team has
also used SHERLOCK to detect antibiotic resistance
genes in Klebsiella pneumoniae bacteria, and health -
related gene variants in human saliva.
For this study, the team, which
also included Bernard Crespi, an evolutionary biology professor at Simon Fraser University in British Columbia, and East Carolina University evolution professor Kyle Summers, focused on 76
gene variations most strongly
related to schizophrenia.
New research reveals that
genes related to the debilitating disorder may
also provide developmental advantages
Researchers observed that the set of
genes involved in memory consolidation coincided with the
genes regulating Crtc1, a protein which
also controls
genes related to the metabolism of glucose and to cancer.
Future inquiry
also relates to cephalopod
genes and regulation relevant to the development and functioning of the nervous system.
They
also found no increase in the levels of angiogenesis - inducing factors or in the expression of angiogenesis -
related genes in metastatic lymph nodes.
The Australian team
also hunted out bipolar -
related genes in this way, but they went further.
The treated rodents were not only fatter but
also suffered elevated levels of fasting insulin, and alterations in
genes related to liver regeneration and detoxification — effects consistent with metabolic disorders in obese patients.
... The FOXP2
gene has been around for a very long time, found in similar form in distantly
related vertebrate species, and it may be important not only for brain development and function but
also in other tissues.»
As well as Zika virus, the team has
also used SHERLOCK to detect antibiotic resistance
genes in Klebsiella pneumoniae bacteria, and health -
related gene variants in human saliva (Science, DOI: 10.1126 / science.aam9321).
Originally, however, they were not examining brown fat thermogenesis, but instead were looking for clues to the function of ERRβ, a protein about which little was known at the time, except that it was closely
related to ERRα, appeared in brown fat cells, and
also worked as a so - called nuclear receptor — a molecular switch for
gene activation that can be turned on by small lipophilic molecules or a signaling protein partner.
The researchers
also found that
genes related to circadian rhythms (the body clock) were changed in mice exposed to e-cigarettes.
«If you can find a
gene for blond hair that exists in Melanesia and nowhere else,» Myles says, «then there's no reason why those sorts of
genes don't exist all over world in underrepresented populations, and affect not only hair pigmentation, but
also disease -
related traits.»
The ultimate outcome of their work might be not only the breeding of quinoa varieties with an even higher salt tolerance but
also the crossbreeding of salt tolerance
genes into
related crop plants such as sugar beets or spinach.
The mutated
genes also interfered with how the brain's layers and halves
relate to one another, a phenomenon confirmed by previous imaging studies of the autistic brain.
The research team found that compared to bony fishes, the four species of sharks and ray examined not only had a much higher proportion of
genes involved in antibody - mediated immunity, but
also that several of the infection immunity -
related genes were expressed only in the sharks and rays.
SAN FRANCISCO, CA — A scientific team led by the Gladstone Institutes and UC San Francisco has discovered that a common form of a
gene already associated with long life
also improves learning and memory, a finding that could have implications for treating age -
related diseases like Alzheimer's.
By 2008, when Moir stumbled on the parallels between amyloid - beta and LL - 37, Tanzi had discovered additional
genes associated with Alzheimer's that were
also related to innate immunity, the part of the human immune system that is shared with worms, flies, spiders and other primitive creatures.
His group
also uses novel genomics approaches to identify
genes related to flavor and disease resistance.
For example, when his psoriasis flared up, the expression of
genes related to inflammation and other immune responses
also increased.
In addition, the researchers
also found that bacteria that are closely
related to one another have similar resistance
genes, which might be expected as bacteria pass their
genes from one generation to the next.
«Finding a SIRT3
gene mutation linked to metabolic syndrome is a big step towards developing treatments for this increasingly common collection of obesity -
related illnesses,» said Dr. Verdin, who is
also a UCSF professor of medicine.
They will
also be able to look for
genes associated with age -
related cognitive decline.
b. Creating synthetic receptors or signals of cancer, i.e. when cancer
related miRNA is activated, you have it
also activate a synthetic
gene or protein, that is expressed on the membrane surface to activate apoptosis.