Sentences with phrase «related markers of inflammation»

Not exact matches

«Results from our study suggest that although CSF markers of inflammation are strong predictors, both plasma and CSF markers of inflammation independently relay information about AD - related pathology and neuronal damage in head - to - head comparisons,» Bettcher said.

However, whether markers of inflammation in the blood (i.e., «peripheral» inflammation) were related to known measures of AD - related pathology, even after accounting for CSF levels of inflammation (i.e., «central» inflammation), remained unclear.

The scientists had expected inflammation markers in the CSF to be more robust predictors of AD - related pathology and neuronal damage than those in the blood due to the «blood brain barrier.»

The research, published in PLOS ONE, found that several markers of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude and that this change was related to increased blood levels of markers of inflammation and oxidative stress.

The findings were related to serological markers of inflammation, T - cell activation and CMV seropositivity.

Boswellia Extract: Clinical studies have shown boswellia to lower levels of inflammatory markers by modulating the production of pro-inflammatory enzyme 5 - LOX, which is common in joint discomfort and other inflammation - related concerns.

The scientists concluded that «The mechanisms of benefit of the tomato - rich diet are not directly related to inhibition of markers of vascular inflammation».

Although limited data are available that directly relate the intake of PHVOs to inflammation, some investigators have reported a positive association between TFA intake and markers of systemic inflammation.

Some studies also found that it helped reduce markers of oxidative stress and inflammation, related to the development of cardiovascular disease 4, 19, 20.

Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction

Depression, inflammation, and the clustering of metabolic risk markers indicate abnormal functioning of stress - sensitive systems.9 These 3 conditions also predict age - related diseases.

First, low SES in childhood is a recognized risk factor for age - related disease, such as cardiovascular disease.24 Childhood socioeconomic disadvantage predicts age - related - disease risks, such as elevated inflammation levels and the clustering of metabolic risk markers in adulthood.25 - 27 In contrast, the effect of low childhood SES on later depression risk is debated.28 Second, retrospective investigations and some prospective studies have shown that childhood maltreatment could contribute to age - related - disease risks.

These abnormalities tend to cluster in the same individuals.18, 19 Evidence shows that the clustering of metabolic risk markers in adulthood is associated with elevated risk of developing cardiovascular disease, diabetes, and dementia in later life.18, 20 Importantly, depression, inflammation, and the clustering of metabolic risk markers frequently co-occur in the same individuals, and their co-occurrence is associated with the greatest disease risk.20, 21 To improve life quality in aging populations, it is critical to gain a better understanding of the origins of these 3 age - related - disease risks.

Interventions targeting modifiable risk factors (eg, smoking, inactivity, and poor diet) in adult life have only limited efficacy in preventing age - related disease.3, 4 Because of the increasing recognition that preventable risk exposures in early life may contribute to pathophysiological processes leading to age - related disease, 5,6 the science of aging has turned to a life - course perspective.7, 8 Capitalizing on this perspective, this study tested the contribution of adverse psychosocial experiences in childhood to 3 adult conditions that are known to predict age - related diseases: depression, inflammation, and the clustering of metabolic risk markers, hereinafter referred to as age - related - disease risks.

Because previous research has shown that depression, inflammation, and the clustering of metabolic risk markers have cumulative effects on clinical outcomes, 20,21 we summed these 3 age - related - disease risks for each Dunedin Study member and found that 59.5 % of study members had none of the risks, 30.2 % had 1 risk, and 10.3 % had 2 or more risks.