Sentences with phrase «related oxidative»
Anthocyanins can protect against — and even reverse — declines in cognitive function due to age - related oxidative stress (Joseph 1999, Lila 2004, Mercola 2012).
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Search out underlying causes of non-exercise or non-productive exercise related oxidative stress and eliminate them.
Protective effects on plaque - related oxidative damage were reported, giving hope for potential therapeutic use.
The chemistry of the mitochondria is also the primary source of free radicals that result in age related oxidative damage.
Not exact matches
to reduce oxidative stress linked to age - related memory loss and inflammation related to brain disorders.
In fact, the omega - 3's in flaxseeds, (which are known as ALA omega - 3 fats), have even been shown to reduce oxidative stress linked to age - related memory loss and inflammation related to brain disorders.
The oxidative damage caused to normal cells by free radicals has been linked to chronic conditions like cancer, heart disease, and degenerative diseases related to aging.
A dozen years later, he's still pursuing that vision: As a first - year grad student, he is investigating whether interventions that reduce oxidative damage could stretch longevity or ameliorate age - related diseases.
The team's laboratory research will also focus on expanding the sensing capability of the bandage to other treatment - related parameters — such as pH, bacterial load, oxidative states and specific disease markers — and incorporating an on - demand drug release capacity.
The UMD and UMB team, led by research associate Eunkyoung Kim, used a discovery - driven approach based on the assumptions that chemical biomarkers relating to oxidative stress could be found in blood, and that they could be measured by common electrochemical instruments.
When researchers screened a library of more than 200 drugs and related compounds for activity against embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress in tumor cells.
The researchers suspect that the related human enzymes might also use the complicated process that the mold employs to carry out their own oxidative reactions.
The research, published in PLOS ONE, found that several markers of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude and that this change was related to increased blood levels of markers of inflammation and oxidative stress.
Among the most interesting ones identified were those associated with 1) the large category of transport, and the more specific categories of carbohydrate transport and cation: amino acid symport; 2) several related to calcium, including calcium ion binding, calmodulin binding, and voltage gated calcium channel activity; 3) DNA damage response and signal transduction; 4) response to oxidative stress; and 5) oxygen and reactive oxygen species metabolism.
Impaired transcriptional activity of Nrf2 in age - related myocardial oxidative stress is reversible by moderate exercise training.
Sirt3 mediates reduction of oxidative damage and prevention of age - related hearing loss under caloric restriction.
This work aims to investigate, mechanistically, the molecular processes related to dysregulation of factors that normally protect the eye against oxidative stress, thus impairing RPE and photoreceptor cellular metabolism and their survival in AMD.
Calcitonin gene - related peptide; Type II alveolar epithelial cell; Oxidative stress; Lung injury; Wnt7b; β - catenin
Besides lipotoxicity (see section V.N) many other molecular mechanisms are involved, including mitochondrial dysfunction, oxidative stress, intramyocardial inflammation, involvement of the reninangiotensin system, altered insulin signaling or female - specific cardiac glycogen handling as a response to metabolic stress (308), and sex - hormone related myocardial calcium handling (309).
Large, age - related deletions in mtDNA are likely responsible for the systemic rise in oxidative stress with aging, and for localized but terrible pathologies of skeletal muscle and substantia nigra dopaminergic neurons in aging bodies.
In the summer of 2010, we posted an entry about a significant advance in basic mitochondrial biology that held within it a tantalizing promise: a potentially new approach to obviating the problem of age - related accumulation of mutations in mitochondrial DNA (mtDNA), which are widely suspected to play an important role in the age - related rise in oxidative stress, Parkinson's disease, and age - related muscle degeneration.
These off - target effects may actually be beneficial in treating IBD, primary sclerosing cholangitis, primary sclerosing cholangitis / IBD - related CRC, and asthma, whereby a multitude of abnormal signaling involving inflammation, oxidative damage, DNA damage, and apoptotic abnormalities exists to manifest itself into a diseased state.
«They concluded that genetic differences and type of fat in the roundworm diet appears to be associated with longevity, and that the reason roundworms lived longer with MUFA might relate to less oxidative stress, or alteration in signalling pathways at cell level that improved their longevity.
Although many years ago we found that reactive oxygen species (ROS) are required for full expression of hippocampal LTP and memory, it is clear that the aged and diseased brain handle ROS much differently as many studies have pointed to a role for excessive ROS and oxidative stress in age - related cognitive decline and impaired memory associated with Alzheimer's disease (AD).
Oxidative stress is the enemy of a mom looking for a happy pregnancy and healthy postpartum and also for her baby, and has been implicated in miscarriage, diabetes - related congenital malformations, spontaneous abortions, preterm birth, pre-eclampsia, fetal growth restriction and low birth weight, according to this review.
Aging of the retina is linked to increased oxidative damage levels, and oxidative stress is believed to play a crucial part in the development of age - related macular degeneration.
Experts say that oxidative stress, chronic inflammation and mitochondrial dysfunction related to aging can all contribute to the problem.
Calorie restriction with a high fat diet effectively attenuated inflammatory response and oxidative - stress related markers in obese tissues of the high diet fed rats https://www.hindawi.com/journals/mi/2012/984643/citations/ 4.
Alcohol can have a strong impact on the production of oxidative stress, because it is not metabolized in the liver — leading to alcoholic liver disease.6, 7 The development of oxidative stress is also related to smoking, which suppresses the immune response and damages lung function.8 What may seem like a surprising factor is the use of pharmaceutical drugs and radiation.
Background: Several studies suggest that carbohydrate nutrition is related to oxidative stress and inflammatory markers.
These two carotenoids normally accumulate in the macula of the eye to protect it from photo - oxidative damage and diseases like age - related macular degeneration.
Aging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aging.
Studies of both elderly subjects and cancer patients have found that the aging and disease related loss of skeletal muscle mass, or sarcopenia, is significantly related to the oxidative shift in the plasma thiol / disulfide redox status.
The first quote I would like to feature considers concepts I have discussed previously in this series that relate to insulin / glucose metabolism in the context of mitochondrial function and oxidative activity:
«In addition, the role of mitochondrial dysfunctions, defects of the endolysosomal and autophagic systems, neuroinflammation, oxidative stress, altered insulin signaling in the brain, and increased permeability of the blood - brain barrier in AD - related neuropathology has been investigated as well.»
These foods increase blood flow to the brain and protect brain cells from oxidative stress and also decrease the effects of age - related conditions like dementia and Alzheimer's (study on blueberries and Alzheimer).
In fact, the omega - 3's in flaxseeds, (which are known as ALA omega - 3 fats), have even been shown to reduce oxidative stress linked to age - related memory loss and inflammation related to brain disorders.
to reduce oxidative stress linked to age - related memory loss and inflammation related to brain disorders.
However, most health benefits of kola nut are due to caffeine, an antioxidant substance that acts as a free - radical scavenger, helping delay oxidative damage related to aging.
Studies suggest that lutein and zeaxanthin help to protect photoreceptors from oxidative stress9.These caroteoids are highly recommended for not only the prevention of age - related macular degeneration, but also to protect against diabetic retinopathy.
Regular exercise reduces oxidative stress - related disease.
− it has anti-inflammatory and antioxidant effects; − its potassium load helps the natural detox function of our bodies; − despite its sweet taste, it actually regulates the blood sugar levels giving the high amounts of fiber it contains; − it contains special starch - related molecules with antibacterial and antifungal properties; − its unique storage proteins, sporamins, prevent oxidative damage to our cells.
Oxidative damage is behind many aging related problems.
Furthermore, it is known that older follicles have fewer defenses against cellular damage caused by oxidative stress, and that this is related to poorer IVF outcomes.
Some studies also found that it helped reduce markers of oxidative stress and inflammation, related to the development of cardiovascular disease 4, 19, 20.
Free radicals and oxidative stress are implicated as a cause of type 2 diabetes, and are also responsible for diabetes - related complications.
Premature aging associated with chronic nervous tension is also related to increased oxidative stress, For example, in a remarkable animal study, examination of the brains of sacrificed animals showed that 85 % of the brain cells observed in the animals exposed to chronic stress showed signs of degeneration.
That finding is important because lutein and beta - carotene are key nutrients in the protection of our body from oxidative stress and health problems related to oxidative stress.
A powerful antioxidant should contain a complex of broad spectrum flavonoid antioxidants and phenolic acids which are proven to slow down the aging process — not just the visible signs of aging, like fine lines and wrinkles, but the critical hidden oxidative stress damage that is linked to a host of age related degenerative diseases such as arthritis, cancer, heart disease, diabetes, cognitive function and strokes.
Antioxidants will be critical for fending off free radical damage and making sure that you aren't putting yourself at risk for oxidative related disease.