Sentences with phrase «related oxidative damage»

Protective effects on plaque - related oxidative damage were reported, giving hope for potential therapeutic use.

The chemistry of the mitochondria is also the primary source of free radicals that result in age related oxidative damage.

Not exact matches

The oxidative damage caused to normal cells by free radicals has been linked to chronic conditions like cancer, heart disease, and degenerative diseases related to aging.

A dozen years later, he's still pursuing that vision: As a first - year grad student, he is investigating whether interventions that reduce oxidative damage could stretch longevity or ameliorate age - related diseases.

Among the most interesting ones identified were those associated with 1) the large category of transport, and the more specific categories of carbohydrate transport and cation: amino acid symport; 2) several related to calcium, including calcium ion binding, calmodulin binding, and voltage gated calcium channel activity; 3) DNA damage response and signal transduction; 4) response to oxidative stress; and 5) oxygen and reactive oxygen species metabolism.

Sirt3 mediates reduction of oxidative damage and prevention of age - related hearing loss under caloric restriction.

These off - target effects may actually be beneficial in treating IBD, primary sclerosing cholangitis, primary sclerosing cholangitis / IBD - related CRC, and asthma, whereby a multitude of abnormal signaling involving inflammation, oxidative damage, DNA damage, and apoptotic abnormalities exists to manifest itself into a diseased state.

Aging of the retina is linked to increased oxidative damage levels, and oxidative stress is believed to play a crucial part in the development of age - related macular degeneration.

Alcohol can have a strong impact on the production of oxidative stress, because it is not metabolized in the liver — leading to alcoholic liver disease.6, 7 The development of oxidative stress is also related to smoking, which suppresses the immune response and damages lung function.8 What may seem like a surprising factor is the use of pharmaceutical drugs and radiation.

These two carotenoids normally accumulate in the macula of the eye to protect it from photo - oxidative damage and diseases like age - related macular degeneration.

Aging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aging.

However, most health benefits of kola nut are due to caffeine, an antioxidant substance that acts as a free - radical scavenger, helping delay oxidative damage related to aging.

− it has anti-inflammatory and antioxidant effects; − its potassium load helps the natural detox function of our bodies; − despite its sweet taste, it actually regulates the blood sugar levels giving the high amounts of fiber it contains; − it contains special starch - related molecules with antibacterial and antifungal properties; − its unique storage proteins, sporamins, prevent oxidative damage to our cells.

Oxidative damage is behind many aging related problems.

Furthermore, it is known that older follicles have fewer defenses against cellular damage caused by oxidative stress, and that this is related to poorer IVF outcomes.

A powerful antioxidant should contain a complex of broad spectrum flavonoid antioxidants and phenolic acids which are proven to slow down the aging process — not just the visible signs of aging, like fine lines and wrinkles, but the critical hidden oxidative stress damage that is linked to a host of age related degenerative diseases such as arthritis, cancer, heart disease, diabetes, cognitive function and strokes.

Antioxidants will be critical for fending off free radical damage and making sure that you aren't putting yourself at risk for oxidative related disease.

In case of oxidative stress in the body, the buildup of damaging free radicals have a known role to play in causing insulin resistance and exaggerating diabetes related complications.

These molecules are critical for the body to limit oxidative stress related damage to the vital organ systems.

Indeed research has indicated that many age - related problems are caused by declining levels of melatonin, which leave the body less able to prevent and repair oxidative damage.

Unique «Mitochondrial Antioxidant» Fights Premature Aging By Jim English Alpha - lipoic acid (ALA) is a unique, vitamin - like antioxidant that can combat radiation sickness, repair damaged livers, treat diabetes and diabetes - related conditions (polyneuropathy) and protect against oxidative processes that promote premature aging and degenerative diseas >> Read Article