Sentences with phrase «related systemic disease»

It includes the Rheumatology Clinical Research Unit, which currently is conducting clinical trials of novel therapies for lupus, rheumatoid arthritis, IgG4 - related systemic disease and osteoarthritis.

Not exact matches

To date, the only known disease related to gadolinium injections is nephrogenic systemic fibrosis, a condition only occurring in a tiny subgroup of patients with renal failure.

They plan to use these proteins to deliver effective substances locally, avoiding systemic complications and are currently working on conditions related to the oral cavity, focusing on anti-caries and periodontal disease.

Insufficient or excess complement activation has been shown to be important in a wide range of disease states, such as multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, and age - related macular degeneration, as well as in allograft rejection.

For example, impaired regulatory systems leading to systemic inflammation, and excessive stress responsivity, are related to biological aging1 and may partly underlie pathogenesis of cardiovascular2, 3 and Alzheimer's 4, 5 diseases (AD).

Systemic inflammation is a major risk factor for a host of lifestyle - related diseases and conditions, including cardiovascular disease and stroke.»

Getting more of these supplements into your diet will greatly lower systemic inflammation and make it easier for your body to fight age related disease and illness.

Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function, as in «leaky gut syndrome,» can result from a number of causes including: • Low gastric acid production • Chronic maldigestion • Food allergen impact on bowel absorptive surfaces • Bacterial overgrowth or imbalances (dysbiosis) • Pathogenic bacteria, yeast or parasites and related toxic irritants • The use of NSAIDs and antibiotics Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination.

Although periodontal diseases have not been «officially» recognized as a complication of DM, the scientific evidence available indicates that poor metabolic control may increase the risk of gingivitis and periodontitis [2]; these periodontal pathologies have also been asso - ciated with diverse systemic diseases closely related to DM, such as cardiovascular diseases, obesity and metabolic syndrome [3][4].

Although greater early local production of proinflammatory cytokines at wound sites is beneficial because it is associated with enhanced healing, greater systemic production of proinflammatory cytokines can represent a maladaptive response.24 Both physical and psychological stressors can provoke transient increases in plasma levels of proinflammatory cytokines, particularly IL - 6,25 as can negative emotions like depression and anxiety.26 - 28 More frequent or persistent stress - related changes have broad implications for physical and mental health; sustained elevated levels of proinflammatory cytokines have been linked to a variety of age - related diseases, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 - 31