Sentences with phrase «related transcription start»
A, schematic representation of serial p21waf1 / cip1 promoter — driven luciferase reporters used in transactivation assay: p21 - Luc contains the 2.3 - kb full - length of p21waf1 / cip1 promoter (from − 2,326 to +10 nucleotide related transcription start site); its derivatives (− 159 / +8) p21 - Luc, (− 123 / +8) p21 - Luc, (− 84 / +8) p21 - Luc, (− 76 / +8) p21 - Luc, (− 63 / +8) p21 - Luc, and (− 56 / +8) p21 - Luc contain a series of deleted promoters of p21waf1 / cip1.
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Multiple Sp1 sites (Sp1 - 1, Sp1 - 2, Sp1 - 3, and Sp1 - 4) located at − 123 to − 63 related to transcription start site are essential for the transactivation of DDX3 on p21waf1 / cip1 promoter.
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