This is a genetic weakness, believed to be caused by
the relatively small gene pool that was necessary to breed for specific characteristics (both physical and mental).
Not exact matches
Gene therapy has the potential to save lives, but the
pool of people who suffer from the orphan diseases, or conditions that pharmaceutical companies have historically ignored, is
relatively small.
However, dog breeds generally are characterized by closed breeding and
relatively isolated populations, often with a
small number of founders and popular sires whose
gene pool is overrepresented in modern - day progeny.