Sentences with phrase «relatively small numbers of patients»

However, due to relatively small numbers of patients within sub-groups, the researchers caution that they did not find definitive evidence to show that effects of vitamin D supplementation differ according to baseline vitamin D status.

«We look for activity of our molecules in phase 2, and on numerous occasions we generate statistically significant data with relatively small numbers of patients, which gives us reasonable confidence that the program will be successful in phase 3 with a larger group of patients.

Guideline authors noted, however, that the evidence for the recommendations is weak, since many of the studies had relatively small numbers of patients with similar types of epilepsy and were conducted at only one institution, so the results may not be generalizable to everyone with epilepsy.

The USIDNET registry gathers variables including clinical, laboratory and outcome data, which together provide a health survey of the relatively small number of patients affected by primary immunodeficiency disorders.

This work shows that TREM2 is important not just in the relatively small number of patients carrying mutations, but potentially in all of Alzheimer's.»

Not exact matches

If it works, it could be used in a far greater number of patients than Sarepta's drug, which is approved for a relatively small slice of the DMD patient pool.

David Magnus, PhD, director of the Stanford Center for Biomedical Ethics and professor of medicine and of biomedical ethics, said those concerns resonate beyond treating SMA patients, who represent a relatively small group of people, because competition is fierce for resources to treat patients with any number of illnesses for which new and more expensive treatments are emerging.

Researchers have found that just five strains are overwhelmingly the culprits in more than 3000 samples of resistant S. aureus collected from patients around the world; the small number suggests that relatively few strains can easily develop resistance to antibiotics, allowing scientists to focus on these few and determine what makes them so virulent.

In the first trial (Neurology 2007; 68:51 — 55), 12 weeks of phenylbutyrate treatment produced no beneficial effects, although the small number and relatively large age range of the patients may have hidden a modest effect.

Although the trial was relatively small in terms of the number of patients, it was unusually rigorous in the methods used to analyze heart metabolism, according to Gropler.

Despite their small number, the patients had a relatively consistent pattern of clinical features suggesting the presence of a QRICH1 - associated phenotype.

The biggest reality check of all, however, is that the number of cancers immunotherapy has been proven effective for is still relatively small (though growing)-- and it doesn't work on every patient.

It is at present unknown whether an optimal balance between safety and efficacy can be achieved with the combination therapy of GH and IGF - I, since this combination has been evaluated in only a small number of patient populations and in studies of a relatively short duration.

By the way, I think the reason the cardiovascular problems were not clearly revealed in clinical trials was that the relatively limited number of patients was too small to provide conclusive statistical evidence of an association.