Sentences with phrase «released by cancer cells»

The research, published in Cell Metabolism, identified the role of a particular protein, IL - 6, released by cancer cells even before cachexia manifests.

Not exact matches

And by absorbing the same light that triggers the drug release, the gold nanoparticles could also heat the cancer cells, providing a double punch.

The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes controlling whether or not genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.

NF - kB enables cancer cells to survive the pro-apoptotic influence of tumor necrosis factor that is released by tumor infiltrating macrophages;

Genetic manipulation of exosomes, virus - sized particles released by all cells, may offer a new therapeutic approach to treating pancreatic cancer, according to a study at The University of Texas MD Anderson Cancer Ccancer, according to a study at The University of Texas MD Anderson Cancer CCancer Center.

By blocking CTLA - 4, ipilimumab releases the brake, allowing cell - killing T cells to assault the cancer cells.

The researchers, who released their findings in Cancer Prevention Research Journal, published by the American Association of Cancer Research, used a visualization technique — immunofluorescence — to identify stem cells in the colon of pigs that were fed either a high calorie diet or a standard diet.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

The idea is that the drug, being within the nano - hydrogels, is transported directly to cancer cells where it can be released without damaging other parts of the body, because hydrogels offer the possibility of dosing a myriad of active substances on the site desired and can be administered as dry or swollen hydrogels by different routes: oral, nasal, buccal, rectal, transdermal, vaginal, ocular and parental.

«The cancer stem cells are also recovering during this gap period, induced by PGE2 released from dying cancer cells

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early - detection of cancers, dementia...

Through its various targets, MMP1 promotes not only tumor invasion but also breast cancer colonization to bone by mechanisms that include the release of membrane - bound EGF - like growth factors from tumor cells, leading to activation of EGF receptor signaling and suppression of OPG expression in osteoblasts, which in turn promotes the differentiation and activation of osteoclasts required for bone destruction and enhanced tumor growth in the bone microenvironment (32).

Once taken up by antigen - presenting cells, which help focus the immune system on an invader, the vaccine releases a factor that heightens their attention specifically to the cancer - promoting protein E7, a so - called oncoprotein that not only enables the human papillomavirus to multiply, but potentially cervical cancer cells to do the same.

As cancer cells are destroyed by radiation, they release their proteins into the bloodstream, clearly revealing their identities as cancer cells and, as a result, attracting the attention of the immune system.

In 1993, while at the Sloan - Kettering Cancer Center in New York, Rothman performed the key experiment that has forever linked his work to that of Thomas Südhof and Richard Scheller, by demonstrating that the same molecules that control this process in the nervous system, in the release of signaling molecules called neurotransmitters, are important to vesicle transport and fusion in all cell types.

Inhibition of growth, production of insulin - like growth factor - II (IGFII), and expression of IGF - II mRNA of human cancer cell lines by antagonistic analogs of growth hormone - releasing hormone in vitro.

Here, we show that in noninvasive human breast cancer cells, disruption of this complex by knocking down LARP7 releases P - TEFb, redistributing it to the transcriptionally active SEC complex.

A research team, led by Dr. William Kaelin at the Dana - Farber Cancer Institute in Boston, recently discovered that TNBC cells release glutamate to disable a cancer - stunting enzyme, Cancer Institute in Boston, recently discovered that TNBC cells release glutamate to disable a cancer - stunting enzyme, cancer - stunting enzyme, EglN1.

This cytokine release can affect ECL cells by impairing their secretory function and lead to achlorhydria and subsequently gastric cancer via ECL hyperplasia by increased gastrin stimulation.

Excess aminos — typically the end result of metabolic processes stimulated by the stress - induced release of adrenal hormones — will be available for use by cancer cells].

Dr. Zihai Li, of the University of Connecticut Stem Cell Institute, said in a news release that by immunizing the host with stem cells, the researchers were are able to «fool» the immune system to believe that cancer cells are present and thus to initiate a tumor - combating immune program.