Sentences with phrase «relevant during disease»

A major challenge in the field of cardiac biology is to decipher the relevance of different signaling mechanisms that are relevant during disease.

However, it is still unclear which of those various pathways are the most relevant during the disease.

Not exact matches

From nearly 35,000 cases during 2008 - 2011, the researchers selected two groups of 9,233 patients with multi-vessel disease that were closely matched in age and other relevant measures.

The insurers maintain that the EL policies only cover mesothelioma which manifested as a disease at some point during the relevant policy period.

Notifies pharmacist of relevant clinical information gathered during calls to provider or patient that may affect a patient's disease state, medication regimen, or method of funding.

Regarding the child, the importance of the intrauterine and early postnatal environments for metabolic programming and modifications of the epigenome is increasingly recognised, 12 — 14 particularly for metabolic diseases such as obesity and diabetes.15 Thus, GDM is related to macrosomia at birth (> 4 kg), to excess body fat and (central) obesity and to insulin secretion in infants and children, the obesity being in part mediated by maternal body mass index (BMI) or birth weight.16 — 23 Intrauterine exposure to GDM also doubles the risk for subsequent type 2 diabetes in offspring compared with offspring of mothers with a high genetic predisposition for type 2 diabetes, but with normal glucose tolerance during the index pregnancy.24 Maternal prepregnancy overweight and excessive gestational weight gain also predict high birth weight and adiposity during infancy.12 25 This is highly relevant, as up to 60 % — 70 % of women with GDM are overweight or obese before pregnancy.26 Finally, maternal lifestyle behaviour such as a high fat diet or lack of physical activity during pregnancy can influence offspring adiposity independent of maternal obesity.12 27