Sentences with phrase «relevant phenotypic changes»

We are known for our cutting edge translational approach to research, our customized solutions, the breadth and quality of our work, as well as for our ability to identify statistically relevant phenotypic changes, even early and subtle changes, that help our clients quantify the efficacy of their treatments before they move into the clinic.

Not exact matches

At present, and based on what we know of the genetic regulation of development, these phenotypic changes in the gut are most likely the result of positive genetic changes in the genetic regulatory pathways controlling the development of the relevant anatomical features, i.e. they are novel positive, heritable genetic features producing a specific and functional novel anatomical structure within the Genus.

The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.