The first is identifying
relevant transcription factors to reprogram stem cells, and the second is finding potential drugs with off - label benefits or adverse effects.
It does this by making sure that
no relevant transcription factors are around to make RNA from the genes.
Not exact matches
Also
relevant are studies of the upstream mechanisms that regulate levels and function of those gene products, for example: how a
transcription factor regulates multiple targets or how
factors can regulate translation or post-translational modification of multiple proteins.
DAXX associates with RelB, a
transcription factor of the NF - κB family that directly controls the expression of numerous apoptosis - and autophagy -
relevant genes, including tumor suppressor protein kinases DAPK1 / 3 [1; 2].