And in a mouse model of Alzheimer's, having more TREM2 in the
brain seemed to
relieve inflammation and amyloid buildup, slow the loss of neurons and preserve the animals» cognitive abilities.
The guidelines provide parameters regarding when clinicians should consider the possibility of ventriculitis (
inflammation of the ventricles in the
brain) or meningitis (
inflammation of the lining of the
brain or spinal cord) in patients who have cerebrospinal fluid shunts and drains (devices placed in the
brain to
relieve pressure due to fluid buildup), intrathecal drug pumps (for administration of pain medicine or other drugs into the spinal canal), deep
brain stimulation hardware (medical devices that provide electrostimulation in the
brain to treat Parkinson's disease or other neurological symptoms) or who have undergone neurosurgery or suffered from head trauma.