Sentences with phrase «remain leukemia»

Our first patients that we reported are just now past their two - year anniversary and they remain leukemia - free, so it remains very promising.

These donor cells also help fight off any remaining leukemia cells, a phenomenon known as the graft - versus - leukemia (GVL) effect.

Not exact matches

«We remain committed to advancing our IDO pathway inhibitor indoximod, which continues to generate exciting data in combination with anti-PD-1 agents, cancer vaccines, and chemotherapy in multiple cancer types including melanoma, prostate cancer, acute myeloid leukemia, and pancreatic cancer.»

The diagnosis of leukemia for the sweetest little pre-schooler of another blogging friend, and the unknown prognosis of yet blog friend after a hair - raising and lengthy hospital stay where questions still remain.

Late last year, even as his leukemia worsened, Walsh, who twice coached Stanford (1977 — 78 and» 92 — 94), remained active in the Cardinal's search.

He remains a leader in supportive care and research in pediatric oncology, with a special focus on neuroblastoma, non-Hodgkin lymphoma, Ewing Sarcoma, acute lymphoblastic leukemia and brain tumors.

June, a professor in immunotherapy at the University of Pennsylvania, described recent triumphs in cancer research that have now been used to treat more than 300 children with leukemia, all of whom remain in remission.

Furthermore, while the approach has shown tremendous promise in treating blood - based cancers like leukemia, solid tumors remain stubbornly difficult to treat with CAR T cells.

While the cause remains largely unknown, only a small fraction of childhood leukemia is believed to involve an inherited genetic predisposition.

«While it has been previously shown that ATRA's ability to degrade the leukemia - causing fusion oncogene PML - RAR causes ATRA to stop the leukemia stem cells that drive APL, the underlying mechanism has remained elusive,» says Lu.

In that study, 3 of 3 patients experienced significant remission of their tumors, and 2 of the 3 remain free of leukemia two years out.

These mutant kinases are attractive therapeutic targets, as demonstrated by the efficacy of imatinib in BCR - ABL — positive chronic myelogenous leukemia (CML), 5 as well as in MPD associated with activating alleles involving PDGFRA or PDGFRB.2, 6,7 In addition, activating mutations in the FLT3 receptor tyrosine kinase are the most common genetic event in acute myeloid leukemia (AML), and specific inhibitors of the FMS - like tyrosine kinase 3 (FLT3) have entered late - stage clinical trials.8 Although mutations in tyrosine kinases and in other genes have been identified in a subset of MPD and AML, in many cases the genetic events that contribute to the molecular pathogenesis of these diseases remain unknown.

In the New England Journal of Medicine, we published the complete genome of another M1 leukemia, this time from a man who's been treated and remains in full remission.

«This remains to be tested, but the findings suggest that alterations in methylation are an important early step in the development of leukemia,» Mullighan said.

Acute myeloid leukemia (AML) is the leading cause of leukemia mortality in the United States.1 Curative treatment involves intensive induction chemotherapy, before proceeding to either consolidation chemotherapy or allogeneic stem cell transplantation based on the patient's risk for relapse.2 This approach has been employed for > 4 decades and, although most individuals achieve complete remissions with front - line therapy, 3 the majority of patients ultimately relapse with drug - resistant disease, and overall survival rates remain disappointingly poor.4 The limited ability of many patients to tolerate the intense chemotherapy - based treatments, in particular hematological toxicity, further contributes to the poor outcomes noted in this disease.

Chemotherapy can never kill off all a person's leukemia cells, so this sort of immunotherapy is important to teach the immune system to find and attack those remaining blood cancer cells, Greer said.

And the dying girl is Rachel (Olivia Cooke), who's been diagnosed with leukemia and spends much of her remaining time with Greg, who has struck up a hesitant friendship with her.

My Sister's Keeper (2009): Anna Fitzgerald looks to earn medical emancipation from her parents who until now have relied on their youngest child to help their leukemia - stricken daughter Kate remain alive.

Many times dogs with chronic leukemia have regular red blood cell and platelet counts, and they remain fairly healthy without treatment.

Feline leukemia and feline aids are highly contagious viruses that can remain latent for years before becoming symptomatic.