Splicing the process by which introns are removed from the pre-mRNA molecules and
remaining exons are joined together, forming the final messenger RNA (mRNA) that is translated into proteins.
Not exact matches
They programmed the new CRISPR / Cas9 system to snip out the dysfunctional
exon, leaving the body's natural repair system to stitch the
remaining gene back together to create a shortened — but functional — version of the gene.
Of the
remaining features, about 75 % represent single -
exon transcripts, leaving 756 and 847 putatively novel multi-exonic genes expressed in the VNO and OM respectively.
The removal of
exon 3 resulted in a deletion of the RNA binding domain and a frame - shift in the
remaining transcript.