Even if you get most of the brain tumour out it comes back again, so we were wondering if you could leave something in the brain cavity that would help target chemotherapy precisely to the tumour to destroy
the remaining tumour cells responsible for the disease coming back.
Not exact matches
The five year disease - free and overall survival rates for patients with high - risk malignant germ
cell tumours remains less than 50 %, and so accurate diagnosis and monitoring is crucial to improving outcomes for patients.
After testing if the
cells remained viable, or alive, after printing, the researchers examined how the
cells proliferated, how they expressed a specific set of proteins that help
tumours spread, and how resistant the
cells were to anti-cancer drugs.
The existence of cancer stem
cells has already been reported in a number of human cancers, explains Professor Jacobsen, but previous findings have
remained controversial since the lab tests used to establish the identity of cancer stem
cells have been shown to be unreliable and, in any case, do not reflect the «real situation» in an intact
tumour in a patient.
When cancer
cells interact with the walls of the blood vessels, EPHA2 is activated and the
tumour cells remain inside the blood vessels.
We are investigating how
tumour cells can disseminate from the primary
tumour and
remain alive but clinically undetectable for many years, and how they start expanding into life threatening cancers in some patients.
Identify and target
tumour cells that
remain dormant for many years after seemingly effective treatment