The Cancer Gene Census (CGC) database contains 547 such gene across various cancer types.5
Remarkably,
few driver genes having specific point mutations appear to be sufficient to rewire signalling networks in cancer, 1 which at the same time shows that — at least from the mutational
side — cancer does not consist of an «infinite» number of different diseases, and in many cases treatment options targeted against driver genes might be transferred from one case to the next.