The gene discovered in the research couples the exocytosis - regulating protein Sec10 with formin, a protein that regulates
the remodeling of the actin cytoskeleton critical to forming cell shapes.
Not exact matches
d) Mechanisms
of host cell
actin remodeling.
Regulation
of A-kinase anchoring protein 79/150 — cAMP - dependent protein kinase postsynaptic targeting by NMDA receptor activation
of calcineurin and
remodeling of dendritic
actin.
Senior author
of the study Xuetong «Snow» Shen, Ph.D., associate professor in The University
of Texas MD Anderson Cancer Center Department
of Molecular Carcinogenesis, developed a unique model system to nail down
actin's function in the nucleus: the
actin - containing INO80 chromatin
remodeling complex in yeast cells.
The F -
actin cytoskeleton is the main driving force
of dendritic spine
remodeling and sustains synaptic plasticity.
We already have evidence that endocytosis is involved in the spatial restriction
of motogenic signals, leading to localised
actin remodelling in response to growth factor stimulation (14).