Sentences with phrase «removing androgen receptors»
Lab tests revealed that removing androgen receptors or ARs from the brain hinders the development of PCOS, whereas eliminating these receptors at an ovarian level still allows the condition to appear.
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When testosterone is given, the need to compensate via increased production of 5α - DHT is removed; the androgen receptors are now also being activated by testosterone, resulting in signaling for reduced synthesis of 5α - reductase and / or reduced 5α - reductase activity.41 In sum, the research suggests that testosterone replacement promotes normalization of 5α - reductase activity, 5α - DHT levels and its metabolism to 3β - adiol.