Sentences with word «remyelination»

These potential reparative functions of AST - OPC1 include the production of neurotrophic factors, the stimulation of vascularization, and the induction of remyelination of denuded axons, all of which are critical for survival and regrowth of — and conduction of nerve impulses through — axons at the injury site.

NYSCF Principal Investigator Dr. Valentina Fossati shared how stem cell technology has revolutionized multiple sclerosis research during the session on remyelination at the Multiple Sclerosis Meeting...

NYSCF Principal Investigator Dr. Valentina Fossati shared how stem cell technology has revolutionized multiple sclerosis research during the session on remyelination at the Multiple Sclerosis Meeting hosted by the ARSEP Foundation in Paris, France.

Systemic factors can also affect these aging - associated events, either positively in which circulating monocytes enhance remyelination in aged mice (11, 12) or negatively in which the accumulation of chemokines in old blood can reduce neurogenesis and cognition in young mice (10).

«Because we found changes in the brain as a consequence of binge eating that were predictive of decreased myelination, therapeutically promoting remyelination may represent a novel treatment avenue for promoting recovery from negative feeding behaviors in eating disorders,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.

«We found that remyelination occurred more efficiently in such mice after they were given Ind - Cl,» Tiwari - Woodruff said.

An evaluation of «IL4I1 augments CNS remyelination and axonal protection by modulating T - cell driven inflammation», recently published in Brain.

In the healthy brain, stem cell - like glial progenitors can divide, migrate to an injured site, and become mature oligodendrocytes after myelin loss, but, unfortunately, the efficiency of remyelination declines with age.

Specifically, it means that remyelination therapies do not need to be based on stem cell transplantation since the stem cells already present in the brain and spinal cord can be made to regenerate myelin, regardless of a person's age.»

As people with MS age, remyelination decreases significantly, eventually causing permanent loss of nerve fibers.

By doing so, they found that the influx of certain immune cells, called macrophages, from the young mouse helped resident stem cells restore effective remyelination in the old mouse's spinal cord.

Accordingly, we investigated whether DN could be improved by local transplantation of MSCs by augmenting angiogenesis and neural regeneration such as remyelination.

Therefore, Gal - 3 influences remyelination by mechanisms involving the tuning of microglial cells, modulation of MMP activity, and changes in myelin architecture.

Between these episodes, the body is sometimes able to repair itself and partial remyelination can occur resulting in remission and improvement in symptoms.

To ensure that the remyelination her team observed in the MS mice was due to Ind - Cl and not to an immune response, the team administered Ind - Cl in mice whose oligodendrocytes, the cells responsible for remyelinating axons and myelin, were selectively decreased.

Better still would be if this drug could stimulate «remyelination,» the re-sheathing of the axons, restoring fast and uninterrupted flow of nerve impulses.