Sentences with phrase «renewal of embryonic stem cells»

The group examined how a protein called a Wnt is believed to maintain the self - renewal of embryonic stem cells.

Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self - renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers.

Not exact matches

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

In parallel, the roles of symmetric and asymmetric cell divisions are investigated as a mechanism for governing stem cell self - renewal and differentiation during embryonic development and in the adult.

Synthetic peptide - acrylate surfaces for long - term self - renewal and cardiomyocyte differentiation of human embryonic stem cells.

It facilitates self - renewal of both pluripotent human embryonic stem cells and induced pluripotent stem cells in a chemically defined, feeder - free and animal - protein free cell culture system.

Banf1 is required to maintain the self - renewal of both mouse and human embryonic stem cells.

A human embryonic stem cell is reined in — prevented from giving up its unique characteristics of self - renewal and pluripotency — by the presence of a protein modification that stifles any genes that would prematurely instruct the cell to develop into heart or other specialized tissue.

Dr. Tajonar obtained her PhD in the laboratory of Prof. Douglas Melton at Harvard University in 2012 where she studied mechanisms of self - renewal and survival in human embryonic stem cells.

«This discovery will advance our understanding of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties of ES cells, and help researchers with the rich source of information to better understand some of the unique features — such as self - renewal and pluripotency — of human embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.

Prior to QB3, she studied mechanisms of self - renewal and survival in human embryonic stem cells in the laboratory of Professor Douglas Melton, completing her PhD at Harvard University in 2012.

Currently, stem cell research focuses on renewal and differentiation of stem cells and the molecular mechanisms of its pluripotency - or their ability to develop into any type of cell - using human embryonic stem cells, induced pluripotent stem cells, and stem cells in simpler organisms.

Many HMTs have been implicated in tumorigenesis and progression of multiple malignancies, and play essential roles in embryonic development and stem cell renewal.

Embryonic stem (ES) cells have high self - renewal capacity and the potential to differentiate into a large variety of cell types.

Studies have identified transcription factors such as Stat3, Nanog, and Oct4 as being necessary for embryonic stem (ES) cell self - renewal and maintenance of pluripotency.