UT Southwestern Medical Center researchers created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to
replenish lost cells.
But in a striking finding, all regenerated heart muscle cells glowed green, indicating that well established cardiomyocytes remaining after injury had likely regressed to a more «youthful» state, started dividing again to
replenish lost cells, and then matured a second time into new heart muscle.
Not exact matches
However, when mature blood
cells are
lost, for example through severe bleeding or during infections, HSCs become activated to generate new «progenitor»
cells — the
cells that
replenish the blood supply and produce immune
cells to fight disease.
«In the future we are hoping to manipulate these
cells to
replenish any
lost retinal neurons, either in diseased or physically damaged retinas,» he noted.
The transplants helped to
replenish the brain by replacing
cells lost due to apoE4, regulating brain activity and improving learning and memory abilities.
This paradigm of harnessing
cells in nearby areas of damage to
replenish lost tissue is not just applicable to the heart; it may be useful in many other organs in the body that have support
cells like fibroblasts.
Another major focus of recovery immediately following exercise has to do with
replenishing energy stores and fluids
lost during exercise and optimizing protein synthesis (the process of increasing the protein content of muscle
cells, preventing muscle breakdown and increasing muscle size) by eating the right foods in the post-exercise meal.
Generally,
losing dead skin
cells through your scalp is a normal and vital bodily function that
replenishes your skin.
These
lost cells are
replenished — like the water from the faucet — by «factory» tissues in the bone marrow.