Sentences with phrase «replication studies in»

However, despite the wide use of the PSC - 17 and the passage of > 15 years, there have been no replication studies in a large national outpatient pediatric sample.

So the question I would like to ask is: would it help to have a formal requirement for publicly funded scientists to do replication studies in addition to their original work?

Maybe, once we see more replication studies in print, we'll be able to judge whether they can filter down to the classroom and improve instruction.

Not exact matches

At the Salk Inst.itute for Biological Studies, in 1994, Leslie Orgel observes, «Because synthesizing nucleotides and achieving replication of RNA under plausible prebiotic conditions have proved so challenging, chemists are increasingly considering the possibility that RNA was not the first self replicating molecule...» (9).

«The philosophical question that has not been answered in origin - of - life studies is this: How can a universe of mindless matter produce beings with intrinsic ends, self - replication capabilities, and «coded chemistry»?

Finally, a Finnish trial of universal home visiting by nurses35 and two U.S. programs implemented by master's degree - level mental health or developmental clinicians have found significant effects on a number of important child behavioural problems.36, 37 Additionally, a paraprofessional home visitation program found effects on externalizing and internalizing behaviours at child age 2; however due to the large number of effects measured in this study, replication of the findings is warranted.38

Although most studies of parental depression have focused on mothers, the impact of depression in fathers has received increasing attention.2, 3 Using data from the 2002 National Comorbidity Replication Survey, the Institute of Medicine report also estimated that 4.3 % of men with a child under 18 years old had a major depressive disorder within the previous 12 months.1 In addition, a recent meta - analysis4 suggested that the prevalence of paternal depression within the first year of a child's life was 10.4 in fathers has received increasing attention.2, 3 Using data from the 2002 National Comorbidity Replication Survey, the Institute of Medicine report also estimated that 4.3 % of men with a child under 18 years old had a major depressive disorder within the previous 12 months.1 In addition, a recent meta - analysis4 suggested that the prevalence of paternal depression within the first year of a child's life was 10.4 In addition, a recent meta - analysis4 suggested that the prevalence of paternal depression within the first year of a child's life was 10.4 %.

In the biggest replication effort so far, «[i] n a report published in Science in August, 270 psychologists orchestrated a repeat of 100 studies published in three top journals.&raquIn the biggest replication effort so far, «[i] n a report published in Science in August, 270 psychologists orchestrated a repeat of 100 studies published in three top journals.&raquin Science in August, 270 psychologists orchestrated a repeat of 100 studies published in three top journals.&raquin August, 270 psychologists orchestrated a repeat of 100 studies published in three top journals.&raquin three top journals.»

By the time he graduated from University College London in 1999, Godinho Ferreira had grown tired of studying replication because the field had reached the point where «people would just repeat each others» experiments,» he says.

The MIME method is groundbreaking in the study of viral replication.

Eventually, with all the replications [of the study], people now recognize that one of the main pathologies in addiction is in the prefrontal cortex.

This study took a different approach — targeting a drug to a protein that controls how genes are turned on and off, early in the viral replication process.

I had spent 4 years studying the interactions between two proteins involved in the cell cycle and DNA replication and repair.

The tools were studied by Dr. Harmand and her colleague Hélène Roche — world experts in lithic analysis, the study of stone artifacts from the various Stone Age periods in which they were made — to interpret physical features and reconstruct the manufacturing techniques used at the prehistoric site, including experimental replication of the tools.

The new study revealed the Ebola VP40 protein assumes different structures to perform multiple roles in the virus's life cycle — membrane trafficking, virus assembly and control of replication.

University of Virginia psychology professor Brian Nosek and his colleagues at the nonprofit Center for Open Science got help from over 350 scientists to repeat 100 high - profile psychology experiments published in 2008 — the largest replication study to date.

Our independent scientific advisory board — all members of which are leaders in their fields as well as advocates on the reproducibility problem — selects studies for replication.

«Isn't it plausible that many or most of the cancers attributed to replication errors in this study involve genetic or environmental factors that are too ubiquitous to be identified as such?»

The authors caution that further study and replication of their results in different populations is needed to verify their model before it will be useful for individual genetic tests — or before longevity «cocktails» are created.

In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the laIn studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the lain cultures of cells grown in the lain the lab.

At Baylor, he studied telomere replication proteins in yeast.

Fishel and Kolodner had been studying the bacteria and yeast genes involved in the repair process that operates when base pairs slip out of alignment during replication, producing mismatches of bases.

The oldest study up for replication is one published in Science in 1960 by Eckhard Hess and James Polt of the University of Chicago in Illinois.

Motyl and his group described the result in the study as «rotten,» but Schimmack — who developed the replication index — is not so pessimistic.

Applicants had to show that the study they wanted to replicate had «cornerstone» status in the field, and that the replication was relevant, with a special focus on impact on health policy and medical guidelines.

So the team made their intentions public by preregistering their study and submitting the idea to a special issue of Social Psychology focused on experimental replication slated to come out in spring 2014.

Over the years, he's seen a number of ways in which replication studies can go wrong in career terms.

The trick, he says, is in seeing replication not as an end in itself but as a means for acquainting yourself with the methods used in a study, the original author's line of thinking, the complications he or she must have faced, and the solutions they devised to those problems.

In this new replication study, recently published in open - access journal Frontiers in Psychology, the Australian team collaborated with researchers in Croatia to repeat their original study with Croatian childreIn this new replication study, recently published in open - access journal Frontiers in Psychology, the Australian team collaborated with researchers in Croatia to repeat their original study with Croatian childrein open - access journal Frontiers in Psychology, the Australian team collaborated with researchers in Croatia to repeat their original study with Croatian childrein Psychology, the Australian team collaborated with researchers in Croatia to repeat their original study with Croatian childrein Croatia to repeat their original study with Croatian children.

Dr. Jones obtained his Ph.D. in 2003 from the University of Birmingham Institute of Cancer and Genomic Sciences (United Kingdom) under Professor Lawrence Young, studying the use of gene therapy for targeting Epstein - Barr Virus (EBV) proteins with replication - competent adenoviruses to treat EBV - driven malignancies.

Previous studies in the lab showed that once HCMV is inside the cell, it quickly becomes latent by entering the cell's nucleus and co-opting a cellular protein called Daxx — part of the intrinsic immune system — to shut down its own replication, the process of reproducing its genetic material to make more copies of itself.

«We now have clues to how that double - ring structure stably lingers until the cell enters the DNA - synthesis phase much later on in replication,» said study coauthor Christian Speck of Imperial College, London.

The findings reinforce the importance of priming effects in gaming and virtual contexts, and the importance of study replication.

One of the genes involved in telomere length was also associated with acne in a replication sample from the UK Acne Genetic study, also lead by King's scientists.

In this study, researchers demonstrated that continued HIV replication in lymphoid tissue sanctuaries refills viral reservoirs in patients on ART who have achieved undetectable blood levels of HIIn this study, researchers demonstrated that continued HIV replication in lymphoid tissue sanctuaries refills viral reservoirs in patients on ART who have achieved undetectable blood levels of HIin lymphoid tissue sanctuaries refills viral reservoirs in patients on ART who have achieved undetectable blood levels of HIin patients on ART who have achieved undetectable blood levels of HIV.

The study offers new information about LASV mutations and its replication in infected individuals that may help scientists understand how the virus causes infection and evades the immune response, and why clinical outcomes can differ so widely.

In HIV - infected patients undergoing antiretroviral therapy (ART), ongoing HIV replication in lymphoid tissues such as the lymph nodes helps maintain stores, or reservoirs, of the virus, a new study funded by the National Institutes of Health suggestIn HIV - infected patients undergoing antiretroviral therapy (ART), ongoing HIV replication in lymphoid tissues such as the lymph nodes helps maintain stores, or reservoirs, of the virus, a new study funded by the National Institutes of Health suggestin lymphoid tissues such as the lymph nodes helps maintain stores, or reservoirs, of the virus, a new study funded by the National Institutes of Health suggests.

They find a role for viral replication in explaining serotype - specific differences in viral load — according to a new study published in PLOS Computational Biology.

However, if the promises of findings reported in the studies by Mahajan and colleagues and Herberg and colleagues are fulfilled by replication and refinement in other rigorous investigations, it may be possible that such advances will further reduce morbidity, mortality, and costs associated with caring for febrile children.

In their new study, the team performed a genome - wide association study (GWAS) on a cohort of 235 Labrador retrievers, together with an independent replication cohort.

The single - center retrospective study was conducted in 644 patients diagnosed as HBeAg - positive chronic HBV (an indicator of active viral replication) with alanine aminotransferase levels within two times of upper normal limit, without evidence of liver cirrhosis.

Pauling denied that the study was a replication of Cameron's experiment because the patients used in the Mayo trial had all received chemotherapy before taking vitamin C so their negative response to treatment with vitamin C may have had more to do with their depressed immune system than the inefficacy of vitamin C.

Dartmouth authors» analysis of GWAS studies published in Human Genetics showed a 1 - 5 percent replication rate.

One of the paper's co-authors, Hugh Willison, who studies GBS at the University of Glasgow in Scotland, says it's possible that something more subtle is happening: Like other viruses, the one that causes Zika hijacks a cell's own replication machinery to make new copies of itself, which then break out of the dying cell and infect neighboring cells.

Before implementing programs based on the new study, Farah says, «we need to invest in replication, fine - tuning, and all the hard work of bringing a program to scale.»

The screening procedure — used in the U.S. to model and study virus replication — allows for continuing evaluation of new antivirals or anti-Ebola drugs, since there is a likelihood of future Ebola outbreaks.

In fact, in a related study published earlier this summer, Jianxin You, PhD, an associate professor of Microbiology who studies viral cancers, showed that the BRD4 protein is a key player in regulating cell replication and the start of canceIn fact, in a related study published earlier this summer, Jianxin You, PhD, an associate professor of Microbiology who studies viral cancers, showed that the BRD4 protein is a key player in regulating cell replication and the start of cancein a related study published earlier this summer, Jianxin You, PhD, an associate professor of Microbiology who studies viral cancers, showed that the BRD4 protein is a key player in regulating cell replication and the start of cancein regulating cell replication and the start of cancer.

The replication crisis refers to a growing concern in experimental psychology — and the larger scientific community — about the drop in studies able to confirm previous work with experiments that achieve the same results using the same methods, as well as the increased risk of data manipulation in studies with small sample sizes.

Pending approval through an Investigative New Drug Application, the aerosolized form of the vaccine will be evaluated for replication, safety and immunity development in a study in adults.

«Online experimentation is the bleeding edge of psychology research, and many believe online studies will play an important role in addressing the so - called «replication crisis» in psychology,» said Ben Motz, senior lecturer and director of undergraduate instruction in the Department of Psychological and Brain Sciences, who has collaborated with de Leeuw.