A 2012 paper co-authored by Ingber, for example,
reported results from a study of a lung - on - a-chip model of pulmonary edema, which can affect cancer patients taking the drug interleukin - 2.
Before
reporting the results from our study, the New York Times journalist obtained feedback from our study's external reviewers as well as from scholars and advocates who support high - stakes testing.
The text of the e-mail
reports results from the study far differently than I would, leaving an impression that is at odds with how I would characterize those results.
Summary: (To include comparison groups, outcomes, measures, notable limitations) This paper
reports the results from a study evaluating an adaptation of the Promoting Alternative Thinking Strategies (PATHS) curriculum for preschool - age children in Head Start.
Not exact matches
Though the
study's
results were self -
reported and were for just one country, in a statement
from the University, Schou Andreassen said, «taking work to the extreme may be a sign of deeper psychological or emotional issues.
Actual
results and the timing of events could differ materially
from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and
studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual
Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
These
results echo a recent Gallup
study showing that employees who work
from home three to four days a week are far more likely (41 percent versus 30 percent) to «feel engaged» and far less likely (48 percent versus 55 percent) to feel «not engaged» than people who
report to the office each day.
Alexion
Reports First Quarter 2018
Results and Positive Topline Data
from ALXN1210 Phase 3 PNH Switch
Study
The company believes that it is on track to achieve its objective of
reporting top - line
results from this important
study before the end of Q3 2018.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial
results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable
results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data
from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified
from time to time in Gilead's
reports filed with the U.S. Securities and Exchange Commission (the SEC).
A survey of New York City employers after implementation of the city's paid sick days law showed that more than 91 percent of respondents did not reduce hiring; 97 percent did not reduce hours; and 94 percent did not raise prices as a
result of the law.26 In a similar
study from Connecticut, which passed a statewide paid sick days law in 2011, employers also
reported no effects or modest effects to their bottom lines.27 And an audit of the District of Columbia's paid sick leave law, effective in 2008, found that it did not discourage business owners
from basing their businesses in the District, nor did it incentivize them to relocate their businesses outside of Washington.28
To date,
results from several longitudinal
studies indicate that e-cigarette use among nonsmoking youth increases the likelihood of future use of conventional cigarettes.5 — 10 Specifically, the pooled odds ratio (OR) in a recent meta - analysis of
studies of adolescents and young adults (aged 14 — 30) indicates that those who had ever used e-cigarettes were 3.62 times more likely to
report using cigarettes at follow - up compared with those who had not used e - cigarettes.11 This finding was robust and remained significant when adjusting for known risk factors associated with cigarette smoking, including demographic, psychosocial, and behavioral variables such as cigarette susceptibility.
The
report, «Carrageenan: New
Studies Reinforce Link to Inflammation, Cancer, and Diabetes,» is the
result of a three - year investigation on the part of the Cornucopia Institute and contains information gleaned
from 1,337 questionnaire responses
from individuals about their own health.
According to
results from our FoodMinds
study, 54 percent of U.S. consumers
report they are actively trying to consume less sugar.
We included prospective
studies that provided hazard ratios (HRs) with 95 % confidence intervals (CI) for at least three categories (including the reference group) of milk consumption in relation to mortality
from all causes, overall cardiovascular disease, or overall cancer, We omitted
studies that only
reported results for total milk products or combined non-fermented and fermented milk because non-fermented and fermented milk may have different associations with mortality.
In all
studies, analyses with glucose AUCi, insulin AUCi, measured meal GI and GL, and II values, with the exclusion of a possible outlier (which was defined as any data point beyond 2 SDs
from the mean value), did not alter
results, and therefore, the data for all subjects who completed all interventions are
reported.
I showed a picture of a child
from Bangladesh who had died as a
result of unsafe bottle feeding, one of the cases
studies in a 2014
report from the Bangladesh Paediatric Association.
Hi Dawn ~ The recent
study from Norway didn't
report this
result — it's a great question.
Although not directly comparable, our findings are in broad agreement with those
from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who
reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content
resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also
reported from an observational
study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.
The increased socioeconomic inequalities in breastfeeding observed in the intervention group supports the argument that population intervention strategies could inadvertently exacerbate, rather than mitigate, socioeconomic inequalities, particularly when the intervention aims to change individual behaviours rather than targeting «upstream» structural changes.25 Our
results are also compatible with an observational
study from Brazil
reporting that breastfeeding rates increased first among the socioeconomically better - off, followed by increases among the poor, over a 20 - year period of active breastfeeding promotion campaigns in Brazil.26
To address the issues above, this paper
reports on the
results of an 18 - year longitudinal
study of the relationships between infant feeding practices and later cognitive ability and academic achievement in a birth cohort of > 1000 New Zealand children
studied from birth to age 18 years.
Research on the impact of depression on home visiting outcomes is mixed with some
studies reporting negative
results while others suggesting that depressed mothers may benefit
from these programs.
In 2007, in an effort to establish whether certain lifestyle factors offered any preventive measure against various types of cancer, the American Institute for Cancer Research released a
report of a meta -
study it had conducted (over five years, compiling
results from several smaller
studies).
May 2011 In an effort to extend the findings of a
study in Nepal that
reported a 44 percent decrease in maternal mortality
resulting from vitamin A or beta carotene supplementation in pregnancy, researchers conducted -LSB-...]
However, much of this evidence relates to singleton infants; although some
studies include multiples,
results are not usually
reported separately, therefore applicability to infants
from multiple pregnancies is uncertain (Renfrew 2009).
However, despite the financial success of these videos, one
study reported that for babies
from 8 to 16 months old, every hour spent watching these videos rather than experiencing human interaction
resulted in their having six to eight fewer words in their vocabularies compared to other babies their age.
Although professional lactation support can improve the duration of overall breast feeding, its effect in improving exclusive breast feeding is unclear.11 18 22 Thus far,
studies that
report improvement of rates of exclusive breastfeeding have involved mainly community based peer counselling strategies.23 24 25 Even then, a randomised trial in the UK recently cast doubt on the efficacy of this approach.26 There are current recommendations
from NICE for the UK - wide implementation of the baby friendly initiative.4 5 6 The 2006 NICE costing
report on routine postnatal care of women and their babies estimates that efforts to improve rates of breast feeding will
result in substantial cost savings for the NHS.6
The prone or side sleep position can increase the risk of rebreathing expired gases,
resulting in hypercapnia and hypoxia.54, — , 57 The prone position also increases the risk of overheating by decreasing the rate of heat loss and increasing body temperature compared with infants sleeping supine.58, 59 Recent evidence suggests that prone sleeping alters the autonomic control of the infant cardiovascular system during sleep, particularly at 2 to 3 months of age, 60 and can
result in decreased cerebral oxygenation.61 The prone position places infants at high risk of SIDS (odds ratio [OR]: 2.3 — 13.1).62, — , 66 However, recent
studies have demonstrated that the SIDS risks associated with side and prone position are similar in magnitude (OR: 2.0 and 2.6, respectively) 63 and that the population - attributable risk
reported for side sleep position is higher than that for prone position.65, 67 Furthermore, the risk of SIDS is exceptionally high for infants who are placed on their side and found on their stomach (OR: 8.7).63 The side sleep position is inherently unstable, and the probability of an infant rolling to the prone position
from the side sleep position is significantly greater than rolling prone
from the back.65, 68 Infants who are unaccustomed to the prone position and are placed prone for sleep are also at greater risk than those usually placed prone (adjusted OR: 8.7 — 45.4).63, 69,70 Therefore, it is critically important that every caregiver use the supine sleep position for every sleep period.
Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others
from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the
results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1
study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.
Only 1 case - control
study from the Netherlands has
reported results.262 This
study did not find an association between usual digit - sucking (
reported as «thumb - sucking») and SIDS risk (OR: 1.38 [95 % CI: 0.35 — 1.51]-RRB-, but the wide CI suggests that there was insufficient power to detect a significant association.
The most recent
study report described in these same regions decreased tissue levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS risk factors, including tobacco smoking.40 These data confirm
results from earlier
studies in humans39, 41 and are also consistent with
studies in piglets that revealed that postnatal exposure to nicotine decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal
studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.
This
study is a sub-sample of
results from a larger
study and the outcomes
reported in the trial registration document are not
reported in this
study, However, the full
study results have not yet been published to be able to judge this outcome.
NYPIRG is basing its
study in part on two Freedom of Information Law requests over the past year that found enforcement actions
from the state BOE have
resulted in «modest fines» levied on committees that filed their disclosures
reports late over the last five years.
While some back - and - forth on
studies is not unusual and is often written in to the contract, according to the sources familiar with the process, the communication related to the contents and timing of the
report that was to
result from the particular methane
study was particularly intense.
The second phase of the
study reports results from 53 healthy, non-obese men and women between ages 21 and 50 who cut calories by 15 % over 2 years and underwent additional measurements for metabolism and oxidative stress.
Women with a history of infertility have a 10 percent increased risk of death compared to those without
reported infertility struggles, according to
results of a new
study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
That
result,
reported in a paper posted online December 1 at BioRxiv.org, directly contradicts a previous
study concluding that tardigrades got about 17 percent of their genes
from bacteria and other organisms.
With this kind of review process, if 20
studies of the effectiveness of a truly ineffective drug are conducted, and one of them shows a significant effect with a p - value of 0.05 because of chance alone, investigators for the other 19
studies not showing any effect would presumably not be inhibited
from writing up and submitting
reports of these for publication out of fear that they'll be denied publication because of their nonsignificant
results.
A recent
study by investigators
from LIJ Medical Center demonstrated that using magnetic resonance imaging (MRI) in men with an elevated prostate specific antigen (PSA)
resulted in a prostate cancer detection rate that was twice as high as data
reported in the March 1999 Prostate journal that analyzed men undergoing the standard 12 - core biopsy with an elevated PSA.
An international research team
reports results of a three - year
study of sediment samples collected offshore
from the Fukushima Daiichi Nuclear Power Plant in a new paper published August 18, 2015, in the American Chemical Society's journal, Environmental Science and Technology.
At a meeting on Earth, my scientists are
reporting a bunch of
results from my Yellowknife Bay
studies.
The journal provides cutting - edge research including
results from animal models that are likely to apply to patients,
studies in human tissue that provide new information about therapies or disease, and innovative
reports of drug discovery and development.
After
studying this
result, the NANOGrav team determined that the
reported non-detection was not a surprise, and
resulted from the combination of optimistic gravitational wave models and analysis of too few pulsars.
«The increased interdependency of countries, economies, and cultures
resulting from tremendous growth in international travel and trade over the last several decades has brought improved access to goods and services, but also a variety of health threats,» said Jendayi Frazer, co-chair of the committee that conducted the
study and wrote the
report and adjunct senior fellow for Africa
studies at the Council on Foreign Relations.
Results from the University of Utah Health - led
study will be
reported at IDWeek, a national infectious disease conference being held in San Diego.
The documentation ranges across the whole spectrum of drug development: Investigators» brochures provide information on all that is currently known about the medicine and so need periodic updating; accurate and concise protocols are required to ensure that trials are performed effectively; clinical trial
reports (generally
from phase II and III
studies) present the information gathered
from the trials; higher level documents provide summaries of efficacy and safety data
from clinical trial programmes; expert
reports provide critical interpretation of the
results; and response documents clarify any points that are not clear to the regulatory agencies or provide additional analyses or supporting data for any items of concern.
Researchers
from the Digital Geography at the University of Helsinki have been
studying whether social media data could be used to understand visitor's activities in national parks and most recent
results are presented in Scientific
reports: Instagram, Flickr, or Twitter: Assessing the usability of social media data for visitor monitoring in protected areas.
Reporting the
results of a second
study from the same group, Dr Suzanne Drury, a translational research and development scientist
from Great Ormond Street Hospital, will describe the team's experience in the use of NIPD (non-invasive prenatal diagnosis) to diagnose the disorder congenital adrenal hyperplasia (CAH).
Dr Eleni Papadopoulou, lead author
from the Norwegian Institute of Public Health, said: «The concern for harm to the fetus caused by radio frequency electromagnetic fields, such as those emitted by mobile phones, is mainly driven by
reports from experimental animal
studies with inconsistent
results.
The researchers say their findings can not necessarily be extrapolated to other countries, although it is likely that similar
results might be found, as
studies from the USA, Australia and Japan have
reported increased suicide risk in adults diagnosed with cancer.