The study used an age - and IQ - matched sample of school - aged youth diagnosed with ASD to assess sex differences according to the standard clinical tests including the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview - Revised (ADI - R), as well as parent
reported autistic traits and adaptive skills.
This
report expands the phenotype of older patients with BRPS; common emerging features include severe intellectual disability (11/12), poor / absent speech (12/12),
autistic traits (9/12), distinct face (arched eyebrows, prominent forehead, high - arched palate, hypertelorism and downslanting palpebral fissures), (9/12), hypotonia (11/12) and significant feeding difficulties (9/12) when young.