When healthy individuals without any previous thyroid disease were fed 30 grams of pickled soybeans per day for one month, Ishizuki, et al.
reported goiter and elevated individual thyroid stimulating hormone (TSH) levels (although still within the normal range) in thirty - seven healthy, iodine - sufficient adults.
Though it was a case
report (and so by definition described only a single patient), it is consistent with data going back more than 50 years, when researchers in Finland blamed the consumption of milk from cows grazing on cruciferous plants for contributing to the national epidemic of
goiter.