Sentences with phrase «reported on clinical outcomes»

In three new studies in the current issue of the International Journal of Infectious Disease, researchers reported on clinical outcomes in the Kingdom of Saudi Arabia (KSA), how long patients will shed virus during their infections, and how the Sultanate of Oman is dealing with cases that have appeared there.

Health Care Reporting Analyst II (2001 — 2004) Performed all design and maintenance of complex Access databases for data administration and reporting on clinical outcomes for the Case Management Department.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Low family income during the early childhood has been linked to comparatively less secure attachment, 4 higher levels of negative moods and inattention, 5 as well as lower levels of prosocial behaviour in children.2 The link between low family income and young children's problem behaviour has been replicated across several datasets with different outcome measures, including parental reports of externalizing and internalizing behaviours,1 - 3, 7 -9,11-12 teacher reports of preschool behavioural problems, 10 and assessments of children based on clinical diagnostic interviews.7

Yang et al. report on one such strategy: Taking the knowledge that an increase in type I interferons (IFNs) correlates positively with clinical outcome in several cancers and that type I IFNs can enhance antitumor immunity in some models, the authors tethered IFN - β to a monoclonal antibody targeting the epithelial growth factor receptor (EGFR), which is approved for use in treating metastatic colorectal cancer and head and neck cancer.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

The study wasn't designed to measure whether tumor profiling made a difference in how patients fared, but «it nonetheless lays the groundwork for more systematic study of the impact of genomics on clinical practice and patient outcomes,» the report said.

In a substudy, review outcomes were also compared across different types of clinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanClinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human tissue.

These risks and uncertainties include, among others, those relating to our ability to obtain sufficient financing to continue as a going concern, the outcome of the review of the continued listing of our common stock on The Nasdaq Stock Market, our ability to develop and market diagnostic products, the level of third party reimbursement for our products, risks related to preclinical and clinical development of pharmaceutical products, including the identification of compounds and the completion of clinical trials, our ability to form collaborative relationships, the effect of government regulation and the regulatory approval processes, market acceptance, our ability to obtain and protect intellectual property rights for our products, dependence on collaborative relationships, the effect of competitive products, industry trends and other risks identified in deCODE's filings with the Securities and Exchange Commission, including, without limitation, the risk factors identified in our most recent Annual Report on Form 10 - K and any updates to those risk factors filed from time to time in our Quarterly Reports on Form 10 - Q or Current Reports on Form 8 - K.

Although earlier reports emphasize that the percentage of NIH extramural grant dollars devoted to clinical research depends on the inclusiveness of the definition of clinical research, 5,14,18,29 the primary purpose of the current analysis was to describe outcomes of the scientific review of grant applications rather than to provide a comprehensive overview of extramural NIH funding for clinical research.

27 Studies cited by the 2010 DGAC Report demonstrate varied metabolic responses to lowered dietary saturated fat, with certain subpopulations exhibiting adverse rather than improved health outcomes.3 Two recent comprehensive meta - analyses indicate that saturated fat is not linked to heart disease.28, 29 In fact, in a definitive review of forty - eight clinical trials, with over sixty - five thousand participants, the reduction or modification of dietary fat had no effect on mortality, cardiovascular mortality, heart attacks, stroke, cancer, or diabetes.30 Yet, avoiding saturated fat remains a cornerstone of national dietary guidance.

eNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

JNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

eNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

JNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

eNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

JNS places special emphasis on articles that provide guidance to clinicians around the world, report cutting - edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.

We report on the development of the evidence base by examining the ACE survey scores in relationship to the established clinical measures of clinical severity, global function, and problem severity collected routinely for children and adolescents referred and accepted for treatment.29, 30 Systemwide implementation of the ACE survey, as a first step, positions CAAMHPP to become an evidence - based, trauma - informed service organization, because ACE survey scores necessarily must relate to clinical outcomes in order to evaluate the effect of trauma - focused interventions in clinical practice.

We previously reported the demographic and clinical characteristics of the mother - child pairs before the commencement of maternal treatment.14 Our focus herein is on the symptomatic and behavioral functioning of the children assessed 3 months after the initiation of treatment of maternal depression by a team of evaluators not involved in maternal treatment and unaware of maternal outcomes.

Low family income during the early childhood has been linked to comparatively less secure attachment, 4 higher levels of negative moods and inattention, 5 as well as lower levels of prosocial behaviour in children.2 The link between low family income and young children's problem behaviour has been replicated across several datasets with different outcome measures, including parental reports of externalizing and internalizing behaviours,1 - 3, 7 -9,11-12 teacher reports of preschool behavioural problems, 10 and assessments of children based on clinical diagnostic interviews.7

So, on the one hand, overweighing rewards associated with certain activities, including gambling itself, can heighten mood and sometimes increase recklessness, consistent with reports that gambling behaviour has a mood regulatory purpose in affected individuals.4 On the other hand, failure to properly balance the impact of rewards and punishment, and the interdiction of cognitive biases including «illusions of control» over the outcomes of probabilistic processes5 may lead to behaviour with consequences that destabilise mood, worsen clinical condition, or increase the risk of relapson the one hand, overweighing rewards associated with certain activities, including gambling itself, can heighten mood and sometimes increase recklessness, consistent with reports that gambling behaviour has a mood regulatory purpose in affected individuals.4 On the other hand, failure to properly balance the impact of rewards and punishment, and the interdiction of cognitive biases including «illusions of control» over the outcomes of probabilistic processes5 may lead to behaviour with consequences that destabilise mood, worsen clinical condition, or increase the risk of relapsOn the other hand, failure to properly balance the impact of rewards and punishment, and the interdiction of cognitive biases including «illusions of control» over the outcomes of probabilistic processes5 may lead to behaviour with consequences that destabilise mood, worsen clinical condition, or increase the risk of relapse.

Summary: (To include comparison groups, outcomes, measures, notable limitations) The goal of the study was to examine whether ISTDP provided by a trained therapist is effective in achieving normalization on standardized self - report measures and whether ISTDP is cost effective when provided by a psychiatrist in a private clinical setting.