Sentences with phrase «reported to effect change»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

LONDON — An influential Tory MEP who helped to draft the biggest change to European finance laws in the last decade says the government's leaked Brexit impact report shows a «consensus» is emerging around the effects of leaving the EU.

But an order was included that demanded such a report pay «extra consideration to the effects such a policy change may have on the middle class, manufacturing and service sector workers, and foreign direct investment into the United States.»

«The edit is only detectable by a slight change in ambience around the one - minute mark — an effect which only adds to the song's sense of dislocation,» reports the BBC.

The new report «Lights Out for the Reef», written by University of Queensland coral reef biologist Selina Ward, noted that reefs were vulnerable to several different effects of climate change; including rising sea temperatures and increased carbon dioxide in the ocean, which causes acidification.

And the effects of the tax cuts will change dramatically after 2025 when individual income tax cuts are scheduled to expire, reported the WSJ.

Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward - looking statements include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; the willingness of health insurance companies and other payers to cover Cologuard and adequately reimburse us for our performance of the Cologuard test; the amount and nature of competition from other cancer screening and diagnostic products and services; the effects of the adoption, modification or repeal of any healthcare reform law, rule, order, interpretation or policy; the effects of changes in pricing, coverage and reimbursement for our products and services, including without limitation as a result of the Protecting Access to Medicare Act of 2014; recommendations, guidelines and quality metrics issued by various organizations such as the U.S. Preventive Services Task Force, the American Cancer Society, and the National Committee for Quality Assurance regarding cancer screening or our products and services; our ability to successfully develop new products and services; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to maintain regulatory approvals and comply with applicable regulations; and the other risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form 10 - Q.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Shares fell last week after Axios reported last Wednesday that Trump was considering changes to the retailer's tax treatment, in part because of anger over how Amazon has hurt the commercial real estate industry because of its negative effect on brick - and - mortar retailers.

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Controversial changes to drug patent and copyright rules required under Canada's recent trade deals will have manageable side effects, according to a new report from the C.D. Howe Institute.

From a strictly legal perspective, the relevant question is not whether there is a sufficient connection to any particular existing or proposed oil sands development or other production activity, and certainly not whether such projects or activities were included in the Terms of Reference (ToR), but rather simply whether the GHGs associated with the production of bitumen that will be transported by the NGP are an «environmental effect» of that project (see NGP Report, Volume II, Appendix 4, Terms of Reference, which defines «environmental effect» very broadly to mean «any change that the project may cause in the environment.»

A draft presidential memorandum at the end of the document that could be used to order the review of NAFTA orders the report to pay «extra consideration to the effects such a policy change may have on the middle class, manufacturing and service sector workers, and foreign direct investment into the United States.»

The financial aggregates are likely to become somewhat more volatile in coming months, due to a change to reporting arrangements that will remove some of the smoothing effect generated by averaging data within individual months.

The way he sees it, The Globe and Mail's Barrie McKenna and Brent Jang reported, markets have reacted to the changes in mortgage rules «in a way which has in effect engineered a soft landing, a much more comfortable kind of situation.»

The December 2016 decision by the PBOC to restrict investment - related FX purchases, however, changed the funding equilibrium (this took effect following the most recent Redfin report, thus not yet visible in most economic data releases as of Feb 17).

Tuesday was also the first day of F8, the social network's annual developer conference, where it was expected to address many of the privacy changes and quality - control measures put in effect since it was reported that data firm Cambridge Analytica allegedly abused the private information of up to 87 million Facebook users for political operations.

These factors — many of which are beyond our control and the effects of which can be difficult to predict — include: credit, market, liquidity and funding, insurance, operational, regulatory compliance, strategic, reputation, legal and regulatory environment, competitive and systemic risks and other risks discussed in the risk sections of our 2017 Annual Report; including global uncertainty and volatility, elevated Canadian housing prices and household indebtedness, information technology and cyber risk, regulatory change, technological innovation and new entrants, global environmental policy and climate change, changes in consumer behavior, the end of quantitative easing, the business and economic conditions in the geographic regions in which we operate, the effects of changes in government fiscal, monetary and other policies, tax risk and transparency and environmental and social risk.

to be sure — is reporting that NASA has changed its data, taking out adjustments for the «urban island effect.»

There has been troll who discovered that CNN changed the effect of the report abuse button from nothing to delayed automatic delete.

Actually, the intial scientific studies (on whether prayer can effect medical outcomes) were both flawed and inaccurately reported - the studies have been revisited and the scientific data to date concludes is that prayer does not change medical outcomes.

Last year, a report by the Oxford Martin School at Oxford University, led by Professor Marco Springmann, said a tax on animal products could have a «substantial» effect in terms of mitigating their contributions to climate change.

A new report and campaign by the environmental group finds that slashing our meat intake by 50 per cent by 2050 is an important way to stop the worst effects of climate change, and the best way to alleviate a raft of health issues linked to eating too much meat.

Therefore it is with regret that I report that I feel the changes in the new standard regarding shade criteria have negative effects and, due to lack of transparency, I can no longer recommend Rainforest Alliance certified coffee to consumers specifically seeking «shade grown» coffee.

Figure 1 shows that the effect of that change was to increase the costs reported for the financial year 2008 - 09 from # 16 billion (as reported in Public Expenditure Statistical Analyses (PESA) 2010 under the old definitions) to # 22 billion (in PESA 2011).

At the Wednesday meeting, Steyer will also sit down with former Treasury Secretary Hank Paulsen and former Housing and Urban Development Secretary Henry Cisneros to confer on a forthcoming report assessing the economic effects of climate change.

By most accounts, council members learned of the new rules through a report on WNBC less than two weeks before the change was to take effect.

«The State's climate policymaking machinery is not measuring up to the task of achieving GHG reduction goals and preparing the state for the effects of climate change,» the commission wrote in a 2017 report to the Legislature.

Landrum and her colleagues demonstrated the effect experimentally and reported the results in a 2017 paper in the Journal of Risk Research entitled «Culturally Antagonistic Memes and the Zika Virus: An Experimental Test,» in which participants read a news story on Zika public health risks that was linked to either climate change or immigration.

Officials said the agreement furthers the objectives of the league's 2014 sustainability report, which documented and disclosed the NHL's carbon footprint, and «NHL Green» — a comprehensive sustainability initiative created by the league in 2010 to address the effects of climate change and freshwater scarcity upon ice hockey as a sport.

«Our research is the first to report trends in injury patterns since «targeting» rule changes took effect.

Short - and long - term impacts The American economy is already beginning to feel the effects of climate change, the report says, and «these impacts will likely grow materially over the next 5 to 25 years and affect the future performance of today's business and investment decisions.»

«There is a tendency to think of depression as a purely «psychological» or»em otional» issue, but it also has physical effects and changes in inflammatory and immune markers have been reported in depressed people,» commented Scott Patten, MD, PhD, the O'Brien Institute for Public Health, Hotchkiss Brain Institute and Mathison Centre for Mental Health Research and Education, Cumming School of Medicine.

Clovis» likely nomination, reported by the farm magazine Agri - Pulse and ProPublica, raised caution among advocates for agricultural research, who say they worry the administration will pay less attention to the effects of climate change on wheat and other vital crops, among other issues.

The results of this study, published this week in the Nature Publishing Group Scientific Reports, allow us to know the effects of climate change on past biodiversity.

The team also reported that climate change has found a second pathway to increase melt over Greenland, adding to the effect of higher temperatures:

The State of the World Population 2009 report says that population levels will affect countries» abilities to adapt to the immediate effects of climate change, although the longer - term influence of population growth on climate change will depend on future economic, technological and consumption trends.

Providing access to contraception for 215 million women, mainly in developing countries, would help to stabilize population growth and significantly reduce the effects of climate change, the United Nations Population Fund (UNFPA) says in a report today.

In the new paper in PLOS Biology, the team reports that the following year, SRF (which had changed its name in 1968 to the International Sugar Research Foundation, or ISRF) launched a rat study called Project 259 «to measure the nutritional effects of the [bacterial] organisms in the intestinal tract» when sucrose was consumed, compared to starch.

The authors of the study, from Shaanxi Normal University in China and York University in Canada, say to maximize this effect media reports should focus on changing people's behavior in an epidemic.

«Many impacts respond directly to changes in global temperature, regardless of the sensitivity of the planet to human emissions of CO2 and other greenhouse gases,» says geoscientist Katharine Hayhoe of Texas Tech University in Lubbock, a co-author of the report, excluding effects such as ocean acidification and CO2 as a fertilizer for plants.

This effect, called structural color, has also been found in chameleons that can «tune» nanocrystals in their skin to change color the way tuning a guitar changes its pitch, as reported in 2015 in Nature Communications.

In place of reporting probit coefficients, we report the marginal effect of the variable on the award probability, which is the change in the award probability due to each predictor separately, with other variables evaluated at their mean values.

A recent Surgeon General's report on e-cigarettes and youth notes that there are significant known deleterious health effects resulting from nicotine exposure in adolescence, including changes to the developing brain.

A recent study published in Scientific Reports, led by researchers of the University of Barcelona in collaboration with several other research institutions, shows that the direct effect of climate change in regulating fuel moisture (droughts leading to larger fires) is expected to be dominant, regarding the indirect effect of antecedent climate on fuel load and structure - that is, warmer / drier conditions that determine fuel availability.

«IPCC report: Climate change threatens irreversible and dangerous impacts, but options exist to limit its effects.»

Global spending to combat climate change fell last year and remains far below the level needed to prevent its most dangerous effects, a report by the Climate Policy Initiative said on Tuesday.

Only two of the 11 models used to project future warming in the most recent report from the Intergovernmental Panel on Climate Change (IPCC) considered the effects of limited nitrogen on plant growth; none considered phosphorus, although one paper from 2014 subsequently pointed out this omission.

According to studies reported in the literature, avocados have the most beneficial effects on lipid profiles, with changes to LDL - cholesterol, HDL - cholesterol, triglycerides, total cholesterol, and phospholipids.

According to the first report under the SECURE Water Act, «As the effects of climate change and snowpack are realized throughout the Colorado River Basin, these effects will drive changes in the availability of natural water supplies.»