Sentences with phrase «reprogram pancreas cells»
Research in mice and human cells suggests that a fasting - mimicking diet may reprogram pancreas cells that are unable to produce insulin and enable them to repair themselves and start making it.
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Eventually, Lim hopes that reprogrammed cells will measure glucose levels in the pancreases of diabetics and trigger a biological insulin response, or even cure cancer.
«Our conclusion is that by pushing the mice into an extreme state and then bringing them back — by starving them and then feeding them again — the cells in the pancreas are triggered to use some kind of developmental reprogramming that rebuilds the part of the organ that's no longer functioning,» says senior author Valter Longo of the University of Southern California School of Gerontology and Director of the USC Longevity Institute.
The researchers used an adeno - associated viral (AAV) vector to deliver to the mouse pancreas two proteins, Pdx1 and MafA, which reprogrammed plentiful alpha cells into functional, insulin - producing beta cells.