Sentences with phrase «reprogrammed human skin cells»

To overcome these hurdles, Bhatia and her team reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.
One week after a breakthrough finding, scientists report they can reprogram human skin cells to behave like embryonic stem cells without a growth factor known to cause cancer
Scientists can now reprogram human skin cells to make working cells that resemble «medium spiny neurons», the type of brain cell that is most affected early in Huntington's disease.
We are improving how we reprogram human skin cells into heart cells, and are investigating the most rapidly evolving areas of the human genome to better understand human disease and evolution.
By reprogramming human skin cells and other cells from patients with neurologic and psychiatric diseases into induced pluripotent stem cells (iPSCs) and induced neurons (iN), his work seeks to decipher the progression and mechanisms that lead to brain cell dysfunction.

Not exact matches

To make the HSCs, the Harvard group used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.
Mouse and human skin cells can be reprogrammed to hunt down tumors and deliver anticancer therapies.
This year they succeeded in generating mini-livers, or liver buds, from stem cells that were taken from human skin and reprogrammed to an embryonic state.
By reprogramming skin cells into nerve cells, researchers at Karolinska Institutet are creating cell models of the human brain.
Two groups of researchers report today that washing human skin cells in similar cocktails of four genes enabled them to reprogram the cells to resemble those harvested from embryos.
The reprogrammed skin cells that have led to this enthusiasm seem to have the same properties as the embryonic stem cells (ESCs) found in human embryos just a few days old.
Similarly, the three research teams that last week reported turning mouse skin cells into embryolike cells say they will have to study embryonic cells to learn how to reprogram human cells in the same way and to understand their potential.
For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary skin cells called fibroblasts.
In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to form small chambers with beating human heart cells.
A new cellular reprogramming method has been revealed that transforms human skin cells into liver cells that are virtually indistinguishable from the cells that make up native liver tissue.
Skin cells from bonobos (pigmy chimps) were reprogrammed to pluripotent stem cells, an advance that allows scientists to study the differences between the neurons of humans and chimps.
Writing in the latest issue of the journal Nature, researchers in the laboratories of Gladstone Senior Investigator Sheng Ding, PhD, and UCSF Associate Professor Holger Willenbring, MD, PhD, reveal a new cellular reprogramming method that transforms human skin cells into liver cells that are virtually indistinguishable from the cells that make up native liver tissue.
Using a process called cellular reprogramming, the researchers take a patient's skin cells, convert them into so - called induced pluripotent stem (iPS) cells, which can differentiate into all the cells within the human body.
Skin cells reprogrammed to act like embryonic stem cells — a breakthrough first reported in human cells 2 weeks ago — are already showing promise as a therapeutic agent.
In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to small chambers with beating human heart cells.
The advantages of this approach began to emerge in 2011, when Dr. Ding announced that he had used his «chemical reprogramming» method to convert human skin cells into brain cells.
However, while hESCs are created from human embryos, iPS cells are cells that were originally from adult tissues, such as skin from an adult body, but have been «reprogrammed» to a hESC - like state.
The crux of the discovery, published online Tuesday by the journals Cell and Science, is a «direct reprogramming» technique that adds a cocktail of four genetic factors to run - of - the - mill human skin cells.
While scientists have successfully reprogrammed different types of mouse cells (fibroblasts, liver and intestinal cells), skin fibroblasts were the only human cell type they had ever tried their hands on.
Gladstone scientists study how human skin cells can be reprogrammed into induced pluripotent stem (iPS) cells, and they are working to refine the production of these cells.
Two studies demonstrate the first direct, chemical reprogramming of mouse and human skin cells into heart muscle and neural cells.
A human heart cell that was chemically reprogrammed from a human skin cell.
Even cooler, scientists are now able to «reprogram» human skin cells from patients with neurological disorders and grow them into brain cells [source: Kavli Foundation].
Other techniques can reprogram «adult» cells in the human body taken from skin, for example — but the cells still carry baggage from their previous state.
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