Not exact matches
«Next, we will explore the therapeutic implications of our discovery by
repurposing available
drugs that block these adenosine receptors and are well tolerated in
humans.»
Medications to block interferon gamma and its effects are already being used in
humans, and Professor Pinschewer is hopeful that the results of the present study will contribute to the
repurposing and successful use of these
drugs in the treatment of hemorrhagic fevers.
Compounds that have already been approved for use in
humans could be
repurposed as anti-tuberculosis medications, and cut down both the time and cost of new
drug development.
Promote
human clinical trials of
repurposed drugs, in collaboration with medical centers (like UC San Francisco) and pharmaceutical companies in the US and abroad.
Once a scientist identifies a
drug that can be
repurposed using the database, the
drug's potential effect must be then tested on a new disease, both in animal models and
human clinical trials.