Substantially increasing the use of staff scientists in this country will thus
require changes in funding and administrative practices as well as culture change.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected
in such forward - looking statements and that should be considered
in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases
in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of
changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest
in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions
in the industries and markets
in which we operate
in the U.S. and globally and any
changes therein, including fluctuations
in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain
in a timely fashion any
required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate
changes on pension obligations; 17) our ability to borrow additional
funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both
in the U.S. and abroad; 20) the effect of
changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and
changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such
changes; 21) any reduction
in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco
in a timely matter while avoiding any unexpected costs, charges, expenses, adverse
changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations
in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European countries that may increase the amount of discount
required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability of
funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations
in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Jackson's own
fund didn't have the capital to mount an offensive, which would
require buying a large stake
in Yahoo and using it as leverage to effect
changes within management.
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or
changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty
fund assessments; uncertainties surrounding participation
in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals
required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed
in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.
If this wasn't enough to get environmentalist
in an uproar the government then proposed
changes to the income tax act that would
require that that charities disclose foreign sources of
funds and demonstrate that the organization satisfied the 10 per cent rule for political activities.
We are deeply concerned that the Investment Company Institute (ICI) Letter lays out a set of
changes to the Proposed Rule which wold effectively negate the derivatives exposure limits
in the rule and render them useless as a tool for controlling speculative leverage at registered
funds, as is
required by the 1940 Act.
«The proposal lacks clear governance arrangements, program specificity and the level of long - term
funding required to achieve sustained behavioural
change,» Mr Baird said
in the letter.
BHA:
Change in Free School model
funding agreement
requires promotion of democracy, equality of opportunity, respect, tolerance and the rule of law
Paterson slammed the Legislature's decision to include a «poison pill» formula
change that would
require an additional $ 600 million
in school
funding along with other spending measures he would otherwise approve
in a veto message signed Wednesday but released to the public on Thursday.
That group spent over $ 16 million between 2011 and 2012, finishing as the state's highest - spending lobby client
in each of those years, but ceased operations when statutory
changes would have
required it to begin identifying who
funded it.
If approved by voters
in the fall, the
change to the charter would
require that all vacant positions held open for one year and a day be eliminated from the following year's budget and the
funding for those jobs returned to the general
fund.
The New York City Council on Wednesday unanimously passed a resolution amending its rules to
require the Council Speaker to make available legislative tracking information data and discretionary
funding data to the public
in a machine - readable format, and City Council members and open government advocates see the
changes as a basis for making legislative information available through an open API.
The plans
require multiple
changes in the state budget, including $ 329 million
in new
funding and $ 120 million
in spending cuts
in a proposed budget of $ 20.729 billion for the fiscal year that starts
in July.
Copelli thinks building a scientific culture
in northeastern Brazil will
require changes in several areas: the way students are taught, the way faculty members deal with
funding agencies, and the federal laws and rules that govern hiring.
«To support this goal and accelerate these efforts,
changes in directions of research support and
funding may be
required,» co-authors Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology, and Jim Allison, Ph.D., chair of Immunology, said
in the review.
The League of Conservation Voters gives McMorris Rodgers a 4 percent lifetime score out of a possible 100
in their environmental scorecard because she has voted against bills that would have
required the federal government to account for the social cost of carbon
in administrative actions and
required federally
funded projects to be resilient to the impacts of climate
change.
If the current
funding does not
change, this will likely
require school leaders and governing bodies to become more confident
in both managing their workforce and
in setting pay policies that enable performance based awards and targeted salaries to retain high quality staff.
During a time of reform for the entire education sector,
funding changes in special education needs provision
require planning.
First, the county board of supervisors slashed
funds for its public schools to $ 150,000, the minimum amount legally
required in 1955 — $ 550,000 less than the nearly $ 700,000 requested by the county school board.9 Along with allocating fewer
funds for the County's schools, supervisors also voted to switch how often they would distribute those
funds,
changing the schedule from an annual basis to a monthly basis.
The
changes require that private
funds used to support a school be disclosed and that complaints about charter school operating procedures be handled
in the same way as complaints about traditional schools are handled.
The proposed bills would
require that LCFF
funding be spent on evidence - based programs and services for high needs students and would
change requirements for the reclassification of English Learners and include them
in the state's Academic Performance Index (API), respectively.
The implementation of new state standards including new English Language Development standards will
require major
changes in teaching and learning for all students including ELs, while the Local Control
Funding Formula gives districts that educate large numbers of ELs additional resources to improve the services that they provide.
I will concede the solutions would need more
funding, but the solutions include
changing the teaching profession,
requiring different expectations at teacher prep programs, reinventing professional development, having a more rigorous human capital department (from hiring to evaluations), more choice, more parent engagement... I also think teaching is not a right, but something you must earn, you should have a society that invests
in the teaching profession and teachers investing
in it too.
«The governor's proposed
changes to ECS and special education
funding, coupled with his proposal to
require towns to pick up one - third of the cost of teacher pension costs, will make it impossible for small towns to
fund education without staggering increases
in local property taxes,» said Betsy Gara, Executive Director of the Connecticut Council of Small Towns.
«The judge's decision means the new
funding rules and other
changes to Florida's education law will
require school boards to be fair and share a portion of their capital improvement dollars with charter schools
in their districts,» said Haag.
In case the mutual
fund wants to
change the asset allocation on a permanent basis, they are
required to inform the unit holders and give them option to exit the scheme at prevailing NAV without any load.
In case the mutual
fund wants to
change the asset allocation on a permanent basis, they are
required to inform the unitholders and giving them option to exit the scheme at prevailing NAV without any load.
or invest 2000 / -
in only one
fund... if one then which (2) pls suggest its ok or
required any
changes....
apartfrom we are doing some long term investment thru mutual
fund (SIP) PLANS are also see is it any
change required in these
funds, we are doing sip from 2 yrs
Thanks for advice i will take a look at balanced
funds also i would like to know there is no
change required for the existing portfolio for the given time frame as i find that instead of franklin small cap
fund others
in the same group are performing better please advice on that issue
Federal regulations
require a daily valuation process, called marking to market, which subsequently adjusts the
fund's per - share price to reflect
changes in portfolio (asset) value.
The
required minimum will be specified as a percentage of the
fund's net assets to be invested
in «highly liquid investments» — meaning cash held by a
fund and any investment that the
fund reasonably believes is convertible into cash
in current market conditions within three business days without significantly
changing the market value of the investment.
Kindly note that the
fund manager of UTI midcap
fund has been
changed, if you have already investd
in this
fund, I would have advised to remain invested for some more time to make a switch (if
required).
As an example, for an index
fund, assets may get liquidated if the underlying index
changes in composition, thus
requiring the manager to sell some stocks and purchase others.
Please advise if i should start SIP
in direct plans of the above mentioned
funds or any
change is
required in the portfolio?
Mutual
fund companies have been
required to post a
fund facts document on their website since 2011, and
changes in 2014
required fund companies to deliver the document within two days of an investor buying a mutual
fund.
While building a retirement
fund requires time, you can accelerate the process by making incremental but positive
changes in your spending habits.
Plan sponsors typically rely on safe harbor provisions
in making
fund changes which
require them to deliver notices to all participants within 30 days of replacing a stand - alone
fund.
But a
change came
in the 1970s with the emergence of money market
funds, which
require no reserve requirements.
To the extent currency exchange transactions do not fully protect a
Fund against adverse
changes in currency exchange rates, decreases
in the value of currencies of the foreign countries
in which a
Fund will invest relative to the U.S. dollar will result
in a corresponding decrease
in the U.S. dollar value of a
Fund's assets denominated
in those currencies (and possibly a corresponding increase
in the amount of securities
required to be liquidated to meet distribution requirements).
I know
changing your life is going to be very uncomfortable, but I think you will find that there is more peace of mind
in having some amount of financial security (which for you will
require a LOT of
changes) than
in borrowing ever more to
fund a lifestyle you can not sustain.
Successful investing is about more than the
funds in your portfolio: it also
requires a
change in thinking.
Except with respect to limitations on borrowing and futures and option contracts, any subsequent
change in total assets or net assets or other circumstances does not
require a
fund to sell an investment if it could not then make the same investment.
Thus, any subsequent
change in values, net assets or other circumstances does not
require the
fund to sell an investment if it could not then make the same investment.
Already equipped with the knowledge and tools to implement
change in its community, the ARL
requires proper
funding so that it can provide education, improve its services, and expand its programs so that it can
change the way Greater Reading understands and manages stray animal populations.
Such a ban would
require funds to compensate fishermen, emergency and long - term
changes in fishing regulations and continual strong enforcement.
The Act, which has passed both houses of the state legislature,
requires that major permits and projects
funded through various state programs consider the impacts of our
changing climate — sea level rise, storm surge and flooding —
in the planning process.
Requires such group, within a year and every four years thereafter, to submit to Congress a report that: identifies gaps
in data and recommends actions to fill those gaps; proposes a coordinated strategy for
funding and allocating responsibilities among federal agencies for climate and other global
change data collection, management, and retention; recommends a federal capital investment strategy; and evaluates optimal design of observation system components to ensure a cost - effective, adequate set of observations detecting and tracking global
change.
(Sec. 479)
Requires each state to prepare a natural resources adaptation plan detailing the state's current and projected efforts to address the potential impacts of climate
change and ocean acidification on natural resources and coastal areas
in order to be eligible for
funds under this subpart.