Sentences with phrase «require immunosuppression»

The unknown is whether the tissue would be rejected in a similar way to kidneys transplanted between unrelated people and require immunosuppression.

As such, PEC - Direct will require immunosuppression therapy, and is being developed for type 1 diabetes patients that are at a higher risk of death due to complications, such as severe hypoglycemic episodes, extreme glycemic lability and hypoglycemia unawareness.

Not exact matches

Liver transplantation is the only therapy for end - stage liver disease, but is not available to everyone, is expensive, requires long - term immunosuppression, and comes with a risk that the body may reject the organ.

This has potential applications for cell replacement without the immunosuppression treatments that are required when cells are transferred between genetically different individuals.

«However, as immunosuppression drugs required for transplantation can have significant adverse side effects, the treatment only makes sense for people who have frequent severe hypoglycemia despite optimal diabetes management, or for those already on immunosuppressant drugs for a kidney transplant, a group being studied in another Phase 3 trial.»

In addition, no immunosuppression is required, so patients would avoid related side effects such as an increased risk of infection.

They possibly have a direct effect on pain mediators such as substance P. Although corticosteroids may be effective in limiting the signs and progression, most dogs require continuous therapy and subsequently develop the concomitant side effects of immunosuppression, weight gain and skin changes.