Sentences with phrase «required higher doses»

The 10 - mg dose of methylphenidate was effective for most students, although some required higher doses for maximum improvement.

The omega - 3s derived from plants however required higher doses for delivering the same effect.

Such opioids could help patients and doctors deal with drug tolerance, a frequent complication in which, over time, patients lose sensitivity to the pain - blocking properties of opioids and require higher doses to treat their pain.

Patients with severe asthma often require high doses of steroid - based treatments that can significantly impair their quality of life.

They are considered an effective treatment for all anxiety disorders, although the treatment of obsessive - compulsive disorder, or OCD, typically requires higher doses.

We concluded that he probably required a higher dose, and since we didn't want to feed him so many high - calorie treats in one sitting, we switched to CBD oil to mix into his food.

If the EQ is < 1, supplementation with 6 - 15 drops of Lugol's solution QD (or 6 - 10 drops of SSKI or equivalent amounts of Iodoral QD [1 tablet of Iodoral = 12.5 mg iodine]-RRB- has clinically been shown to be helpful in promoting conversion of 16α - OH estrone to estriol.2728 Some women initially require high doses of iodine to jump start the conversion of 16α - OH estrone to estriol, after which iodine supplementation can be cut back to lower amounts.

This means that half of the cancer cell lines did not thrive in 20 mmol / L of ascorbic acid, while another half were more resistant and required a higher dose to effectively reduce the population by 50 % (EC50)[16].

Thanks to our current exposure to environmental pollutants, we may also require higher doses of nutrients than any of our predecessors.

Amino acids require high doses to be effective in releasing hGH naturally, according to the studies.

Choline bitartrate dose: General health benefits start registering at lower doses such as 250 - 500 mg, but nootropic boosts may require higher doses such as 1 - 2 grams daily.

He may recommend checking your vitamin D level with a blood test; if you are deficient, you may require higher doses than these recommendations indicate.

As a person takes more and more narcotic pain medications, their tolerance generally increases, requiring higher doses for the narcotic to be effective at fighting pain; the body adjusts to opioids.

«About 50 to 60 % of patients respond to SSRIs, but it usually takes about 10 weeks and requires a higher dose than the treatment of depression,» says Elias Aboujaoude, MD, director of the Impulse Control Disorders Clinic at Stanford University and author of Compulsive Acts: A Psychiatrists Tales of Ritual and Obsession.

More severe pain will require a higher dose, while some dogs may require a higher dose just because their body doesn't react very well to a lower dose.

He had been at a shelter for over a year and had a severe case of gingivitis / stomatitis (inflammation of gums and entire oral cavity) requiring high doses of steroids twice daily to control his pain and allow him to continue to eat.

When starting glucosamine treatment, your dog may initially require high doses of the supplement for there to be a positive effect.

Cons: Not recommended for kittens under eight weeks of age, not recommended for cats under five pounds, larger cats may require a higher dose, some cats have had a bad reaction, some of the product may wash off if the cat bathes within 24 hours of application

These cats require higher doses of iodine 131 to destroy the tumor.

Dogs who start glucosamine treatment often require higher doses than normal for the supplement to begin to show beneficial effects.

Not exact matches

A venture capitalist looks forward with a healthy dose of skepticism because they understand that costs, roadblocks and time required likely will be higher than an entrepreneur anticipates.»

The highest dose that doesn't require a prescription is 40 %.

From what I can tell these require rather high doses of marijuana that are rarely consumed, but I'm not really able to find statistics on this fact and I'm hardly familiar enough with the drug - culture to say personally.

Available over the counter, ibuprofen in higher doses requires a prescription.

Of the patients who received the high dose in study, 11 patients are able to speak, 11 patients are fed orally and seven do not require bi-level positive airway pressure as of the data cut - off (August 7, 2017).

Transient liver toxicity is a significant concern in gene therapy, when high doses are required.

Since it can be abused or toxic if taken in high doses, legal limits have been placed on its use, including requiring new users to report each day to a methadone clinic, and take the medication on site.

They found that higher doses of clonazepam were required to control Dravet syndrome seizures, but lower doses to treat its autistic and cognitive aspects.

Hoge acknowledges that some conditions may be off limits to mRNA drugs simply because they require higher levels of protein than the mRNA can make at a safe dose.

«This new study is the first to test the effectiveness of the higher doses of Genistein, which are thought to be of the strength required to see an effect in the brain.

At the highest dose of DMAU tested, 400 mg, subjects showed «marked suppression» of levels of their testosterone and two hormones required for sperm production.

Finally, these benefits emerged without any adverse side effects, even at SW033291 doses much higher than would be required for 15 - PGDH inhibition.

While antibiotics are often required in high doses and affect the whole body, ATPL treatment can be concentrated on the infected site.

Influenza remains a major health problem in the United States, resulting each year in an estimated 36,000 deaths and 200,000 hospitalizations.4 Those who have been shown to be at high risk for the complications of influenza infection are children 6 to 23 months of age; healthy persons 65 years of age or older; adults and children with chronic diseases, including asthma, heart and lung disease, and diabetes; residents of nursing homes and other long - term care facilities; and pregnant women.4 It is for this reason that the Centers for Disease Control and Prevention (CDC) has recommended that these groups, together with health care workers and others with direct patient - care responsibilities, should be given priority for influenza vaccination this season in the face of the current shortage.1 Other high - priority groups include children and teenagers 6 months to 18 years of age whose underlying medical condition requires the daily use of aspirin and household members and out - of - home caregivers of infants less than 6 months old.1 Hence, in the case of vaccine shortages resulting either from the unanticipated loss of expected supplies or from the emergence of greater - than - expected global influenza activity — such as pandemic influenza, which would prompt a greater demand for vaccination5 — the capability of extending existing vaccine supplies by using alternative routes of vaccination that would require smaller doses could have important public health implications.

Although the shorter therapy requires higher radiation doses, the experts found that this option may result in better quality of life.

Furthermore, direct injection in this small and immunologically privileged site can potentially overcome limitations linked to systemic injection which would require a very high dose to target the CNS and can be neutralized by anti AAV antibodies or may trigger the activation of CD8 + T cell response.

Other radiation treatments that require targeting the tumor from an external source, which exposes healthy tissues and limits how high a dose can be safely delivered.

Doing so may require expansion to meet broader clinical indications or higher dose requirements.

In ZUMA - 1, 12 % of the patients had a grade 3 or higher cytokine release syndrome and that is essentially a patient requiring mechanical ventilation or needing treatment with a high - dose vasopressor.

Since refined carbohydrates such as bread raise blood glucose significantly more than dietary fat, this required higher insulin dosing in type 1 diabetics to keep blood glucose control.

It's not clear why Remicade might be riskier than other TNF inhibitors, but it's possible that the higher initial doses the drug requires might be partly responsible, Dr. Grijalva says.

A slightly higher dose of natural progesterone may be required initially to remove the progestins from the cell receptors.

But as many studies have stated just because something is safe when being consumed as part of a meal, doesn't mean that it is safe when taken in the higher doses required to be effective as a medicine.

This study indicates that very high doses (higher than the daily required intake) of chromium are required to for quick and effective glycemic control in people with type 2 diabetes.

We will be sharing with you the list of best protein rich foods in the upcoming article to serve you with the required daily dose of protein from high protein vegetables and other vegan sources of protein.

In addition to goitrogens, crucifers also contain substances called nitriles that can release cyanide into tissues and result in general toxicity at high doses.15 A 2004 study conducted in Japan suggested that massive doses of nitriles, doses that are impossible to obtain from food, would be required in order to result in toxicity.16 This study used behavioral endpoints such as restlessness to judge toxicity.

But, the required dose of radiation delivered to the chest is so high that a young woman getting just a single scan, for example, may increase her lifetime risk of breast cancer and lung cancer by between around 1 and 4 %.

In short, in order to adapt and overcome the physical stress of training (which makes you stronger) your body requires stress signals — which high doses of vitamin C interfere with.

For that, you have to stack and dose aggressively, which is going to inevitably raise your estrogen levels higher than you want them to be, requiring the addition of estrogen blockers.

It's possible that vitamin B5 can help your skin, but the required dose is so high and the evidence is so thin that it's not worth it.