0 Research ArticleRETINAL DISEASES Human ESC — derived retinal epithelial cell sheets potentiate
rescue of photoreceptor cell loss in rats with retinal degeneration Karim Ben M'Barek 1,2,3, Walter Habeler1, 2,3, Alexandra Plancheron1, 2,3,
Not exact matches
In order to study
rescue effects following surgery, donor
cells were introduced at P21, an age preceding major onset
of photoreceptor loss.
Of note, while vision rescue requires preservation of some functional photoreceptors, the mere presence of photoreceptor cells in the ONL of transplanted RCS rats does not assure function [61
Of note, while vision
rescue requires preservation
of some functional photoreceptors, the mere presence of photoreceptor cells in the ONL of transplanted RCS rats does not assure function [61
of some functional
photoreceptors, the mere presence
of photoreceptor cells in the ONL of transplanted RCS rats does not assure function [61
of photoreceptor cells in the ONL
of transplanted RCS rats does not assure function [61
of transplanted RCS rats does not assure function [61].
Qualitative examination
of the host anatomical response to the presence
of hNPCctx or hNPCctx - GDNF revealed substantial preservation
of the
photoreceptor outer nuclear layer (ONL) overlying all subretinal donor
cells (Figure 5E and F), with
photoreceptor rescue gradually declining outside the distribution
of the transplanted
cells (Figure 5E and G).