The work published in Cancer Cell complements previous
research efforts from the CNIO Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.
Somewhere along the way, we decided that basic science should not be tainted by commercial interests, and, 50 years later, we have effectively insulated the bulk of our national
research efforts from direct engagement with the challenges and opportunities of industry.
Not exact matches
That
research will be crucial: An earlier
effort by another company, Pathway Genomics, to create a «liquid biopsy» for cancer was greeted in September by a stern letter
from the Food and Drug Administration (FDA) warning that the agency had «not found any published evidence that this test or any similar test has been clinically validated as a screening tool for early detection of cancer in high risk individuals.»
Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and
research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services
from suppliers; (8) company and customer - directed cost reduction
efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal
from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
Developing an effective content creation machine requires a team
effort,
from getting team members involved in
research and creation, to reaching out to guest contributors and getting community feedback on themes they want to learn more about.
The two are on their way to meet with Chris Pritchard, a 24 - year - old Ph.D. candidate and Langer protégé, with master's degrees
from Oxford and MIT, who heads InVivo's
research and development
efforts.
Winners also enjoy: National recognition as one of Canada's foremost Dealmakers Heightened market interest thanks to extensive media exposure in The Globe and Mail, Lexpert and Thomson Reuters publications Media coverage stemming
from Deloitte's national media relations
efforts The opportunity to engage in the high - level industry networking that fuels M&A transactions - Recognition at the gala awards ceremony, which is attended by leading investors, advisors and financiers - Year - round networking and educational opportunities, including access to valuable
research, insights and best practices
Given how long it takes to see the fruits of any significant
research effort (Apple's latest iPhone chip was eight years in the making), the risk to
research and innovation
from activists who force deep cuts to drive up the share price and then sell out before the pipeline dries up is obvious.
Our future capital requirements may vary materially
from those currently planned and will depend on many factors, including our rate of revenue growth, the timing and extent of spending on
research and development
efforts and other business initiatives, the expansion of sales and marketing activities, the timing of new product introductions, market acceptance of our products and overall economic conditions.
New
research from the University of North Carolina at Chapel Hill provides valuable insight into the navigation and nesting behaviors of loggerhead sea turtles that could inform future conservation
efforts.
Overall, GVBOT is pleased with the increased funding for
research and
efforts to encourage workforce participation
from underutilized sources of labour.
Going back to the origins of personas and buyer personas as an ethnographic
research effort to inform design and strategy, these meant involving multi-disciplinary groups
from design, branding, corporate strategy, marketing, call centers, fulfillment, and service.
From an in - house perspective, it becomes an ongoing agenda and specific
research efforts often taking a minimum of 3 months to gain the insights needed and to translate into the rich interface of a consumer (user) or buyer persona.
And consider (what first strikes an outsider
from a really secular university) where Notre Dame commits its
research and teaching
efforts.
In an
effort to save you some
research time (and a possible nervous breakdown), we spoke to several admissions counselors
from various types of educational institutions (Christian university, state school, media school and private college) about the most important elements to consider when deciding on a school.
Please enjoy your Nobel Prizes responsibly, lest you accidentally publish your
research somewhere where unsuspecting readers could come across it by accident and have their brains melt
from the sudden
effort...
I don't have much time so I find it easy to get help
from others who have already done the hard work of
research and study and in this modern age it really saves time the youtube and computer certainly are plus in educting our self with the least amount of
effort
«Walnuts have really benefited
from aggressive
research and really smart marketing
efforts by the California Walnut Board, and they have done a great job communicating the health benefits to consumers.
To overcome production constraints through collective
research efforts, the first planning meeting of the Temperate Rice Research Consortium (TRRC) was organized by the International Rice Research Institute (IRRI) at Suwon, Korea, on 2 - 3 May 2007 with the participation of scientists from 12 temperate rice - growing co
research efforts, the first planning meeting of the Temperate Rice
Research Consortium (TRRC) was organized by the International Rice Research Institute (IRRI) at Suwon, Korea, on 2 - 3 May 2007 with the participation of scientists from 12 temperate rice - growing co
Research Consortium (TRRC) was organized by the International Rice
Research Institute (IRRI) at Suwon, Korea, on 2 - 3 May 2007 with the participation of scientists from 12 temperate rice - growing co
Research Institute (IRRI) at Suwon, Korea, on 2 - 3 May 2007 with the participation of scientists
from 12 temperate rice - growing countries.
Improved commercialisation and increased
effort in food processing developments will help Australia profit
from the nation's world leading
research in agricultural systems.
In addition to our relationship with Feeding America, the Del Monte Walnut Creek
Research Center (WCRC) in California received a «RecycleSmart» Award in 2014
from the Contra Costa Solid Waste Authority for our food waste recovery
efforts.
Research from Globescan revealed that 92 per cent of shoppers think food companies should focus their
efforts on securing the future sustainability of food, with two - thirds believing that farmers should be paid more -LSB-...]
Co-founded and jointly led by Stanford University and The Culinary Institute of America, the Menus of Change University
Research Collaborative is a working group of leading scholars, foodservice business leaders, and executive chefs
from invited colleges and universities who are accelerating
efforts to move Americans toward healthier, more sustainable, plant - forward diets.
The MomsTEAM staff and I are still digging into the Institute of Medicine and National
Research Council's three - hundred - some - odd page report on sports - related concussions in youth sports, [1] but one thing jumped out at me at my first pass: When I did a search in the report for a discussion of impact monitoring devices (a / k / a hit sensors), I found only one brief mention of sensors in the committee's recommendation that the Centers for Disease Control fund large scale data collection efforts for research purposes, including data from impact
Research Council's three - hundred - some - odd page report on sports - related concussions in youth sports, [1] but one thing jumped out at me at my first pass: When I did a search in the report for a discussion of impact monitoring devices (a / k / a hit sensors), I found only one brief mention of sensors in the committee's recommendation that the Centers for Disease Control fund large scale data collection
efforts for
research purposes, including data from impact
research purposes, including data
from impact sensors.
So much of putting this issue together came down to doing the
research and soul - searching to really understand the differences between shame and guilt, and shame as a normal emotion and when it crossed into unhealthy territory and the effects of that toxic shame and then the sheer enormity of
effort that must take place for a person to heal
from a shame - based self - image.»
«Global philanthropic support for
efforts to prevent, mitigate, and resolve conflicts totaled $ 283 million in 2013... 288 foundations awarded nearly 2,000 grants in support of more than 1,200 organizations working for peace, justice, diplomacy, and national and global security,
from conducting
research on the prevention of nuclear terrorism to supporting citizen journalism in Egypt.
ZERO TO THREE, in partnership with the Bezos Family Foundation, conducted a comprehensive
research effort, including a series of in - home discussions and a large national parent survey with a diverse range of parents of children
from birth to 5.
In 2007, in an
effort to establish whether certain lifestyle factors offered any preventive measure against various types of cancer, the American Institute for Cancer
Research released a report of a meta - study it had conducted (over five years, compiling results
from several smaller studies).
By Yahoo! Canada Sports (blog) University of Alberta researcher Dr. Dhiren Naidu's findings suggest concussion education... Concussions are a key issue facing the CFL, but new
research from the University of Alberta suggests that some of the league's
efforts on that front are having... See all stories on this topic»... read more
A phone call requires more
effort, and as
research from the Congressional Management Foundation has shown, Hill offices tend to accord them more weight.
Alex Balch has received funding
from the Economic and Social
Research Council, EU and Joseph Rowntree Foundation for research into policy on labour migration and efforts to tackle forced labour and human traf
Research Council, EU and Joseph Rowntree Foundation for
research into policy on labour migration and efforts to tackle forced labour and human traf
research into policy on labour migration and
efforts to tackle forced labour and human trafficking.
The Nigerian Air Force has said that it has intensified
research and development
efforts towards producing locally - made spares and other related equipment for military aircraft in a bid to address the challenges associated with spares procurement
from third party countries.
The facts, as confirmed by ongoing independent quantitative
research, show our
efforts have made great strides in improving perceptions of New York State, creating greater awareness of our economic development programs, increasing the perception that New York is a good or excellent place to do business by 122 percent among executives
from out of state, as well as attracting more tourists to spend their vacations here.
After the hearing, Senator Serino issued a statement, saying that the health department
efforts so far have fallen short and that «more is needed
from our partners at the State and Federal levels» for
research, prevention and to develop more effective testing and treatment options.
Syverud also successfully obtained
from the initiative $ 12.5 million for the National Veterans Resource Complex, part of SU's flagship
effort to transform central New York into the «hub» of
research and programming connected to veterans and military affairs.
The Adirondack Council has viewed Stefanik, a sophomore Republican, as critical in
efforts to preserve
research grant funding for the Adirondack Lakes Survey Corporation (ALSC) in Ray Brook, a nonprofit laboratory that takes samples
from local waterways annually to monitor acid rain recovery.
The most recent of the program's reports, AAAS Report XXIII:
Research and Development FY 1999, is a collaborative
effort involving contributions
from 22 scientific, engineering, higher education, and industrial associations known collectively as the Intersociety Working Group.
The most recent of the program's reports, AAAS Report XXII:
Research and Development FY 1998, is a collaborative
effort involving contributions
from approximately 20 scientific, engineering, higher education, and industrial associations known collectively as the Intersociety Working Group.
«A lack of diversity at the faculty level is an enormous problem in biomedical science, so I applaud HHMI's
efforts to support junior scientists
from underrepresented backgrounds,» writes Jessica Polka, president of the Future of
Research board of directors, in an email to Science Careers.
It's fair to guess he was alluding to
efforts by various elected officials to limit further investment in climate change studies, renewable energy technologies and proposals for outside - the - box basic
research — the type of high - risk but also potentially high - payoff investigations
from which transformative developments most often emerge.
But they are raising concerns about air pollution
from Sarajevo to New Delhi and supplying data to
research efforts.
Hurricanes that devastated areas of the Caribbean last fall impeded science
research and teaching, but new networks for aiding colleagues and new avenues for
research have emerged
from the response
efforts, according to several speakers at a recent conference co-hosted by AAAS.
Each issue features news
from our current
research and updates on what we are learning and how our findings, tools, and resources can be applied to your own
efforts to advance science literacy.
► How intellectual property (IP) ownership is awarded to academics can have a significant effect on their commercialization
efforts, according to a paper
from the National Bureau of Economic
Research that Mervis reported on (subscription required), also in this week's issue.
Toward High School Biology is designed to align closely with a new set of science education standards, called the Next Generation Science Standards, which were developed with help
from 26 states and organizations like AAAS and the National
Research Council, in an
effort to teach students to read scientific texts, analyze data and construct coherent explanations of scientific phenomena.
Prichard's
efforts have attracted support
from pharma giants such as Merck and Glaxo, as well as governmental and foundation backing
from the Natural Sciences and Engineering
Research Council of Canada, Fonds de Recherche de la Nature et des Technologies du Quebec, and the Canadian Foundation for Innovation, to the tune of over $ 12 million in grants.
We were particularly gratified that our
efforts toward broad - based cooperation, both interdisciplinary and in terms of North - South cooperation, received recognition in the form of a
Research Cooperation Award
from WWF and Centre Suisse in 2001.
The
research is a multicontinent
effort with researchers
from North America, Europe and Australia all contributing to the work.
A proposal to study a mysterious object, with no guarantee that the
effort will pay off at the end, is not very appealing to agencies like the National Science Foundation, which expect well - defined goals and concrete results
from the
research projects they support.
In an
effort to find out, Stephen P. Juraschek, M.D., Ph.D.,
research and clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data
from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 1997.