Sentences with phrase «research on animal models»
Lee hopes that her finding will highlight the importance of the cortex for understanding developmental processes in Down Syndrome and spur further research on animal models.
https://www.sciencedaily.com/
Genetic modification in zebrafish models is cheap and easy, so authors point out that future research on these animal models will contribute to understand the molecular relationship that exists between the proteins involved in the physiopathology of megalencephalic leukoencephalopathy.
Not exact matches
The Dr Hadwen Trust for Humane Research claims that «in some instances, reliance on inaccurate animal «models» of human disease have undoubtedly delayed medical progress.»
The key problem for research on smallpox is that there is no good animal model for the disease.
New research from McLean Hospital neuroscientists shows in an animal model that being bullied can have long - term, dramatic effects on sleep and other circadian rhythm - related functions, symptoms that are characteristic of clinical depression and other stress - induced mental illnesses.
It is shocking that Science would take the time and effort to highlight and chronicle the sentiments of someone whose sole mission is to derail biomedical research that is dependent on animal models.»
«Most previous research into ways of delaying the onset of HD symptoms have focused on studying the mutant protein in cells or in animal models, but the relevance of abnormalities in those systems to what actually happens in patients remains a huge assumption,» says James Gusella, PhD, director of the Center for Human Genetic Research (CHGR) at Massachusetts General Hospital (MGH), corresponding author of the Celresearch into ways of delaying the onset of HD symptoms have focused on studying the mutant protein in cells or in animal models, but the relevance of abnormalities in those systems to what actually happens in patients remains a huge assumption,» says James Gusella, PhD, director of the Center for Human Genetic Research (CHGR) at Massachusetts General Hospital (MGH), corresponding author of the CelResearch (CHGR) at Massachusetts General Hospital (MGH), corresponding author of the Cell paper.
Its research includes a cluster of related interdisciplinary projects that examine disparities in breast cancer mortality between African - American and Caucasian women using animal models, molecular characterization of tumors, and behavioral research focused on social - environmental factors.
«We have demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver of the adult offspring, raising new concerns about the long - term metabolic complications in children born to women who take SSRI antidepressants during pregnancy,» says PhD student Nicole De Long, who presented this research on June 22nd at the joint meeting of the International Society of Endocrinology and The Endocrine Society.
The journal's home page explains that translational medicine «builds on basic research advances — studies of biological processes using cell cultures, for example, or animal models — and uses them to develop new therapies or medical procedures.»
In the study, Bruce Hope, from the National Institutes of Health National Institute on Drug Abuse Intramural Research Program in Baltimore, Maryland, and colleagues used animal models to investigate if the brain forms drug - related memories in a similar way.
Research on Huntington's has thus far relied heavily on animal models of the disease, and has left many key questions unanswered.
«Although this is basic scientific research using animal models, these studies are shedding light on the molecular mechanisms that control male fertility, and are helping us to better understand the causes of many cases of infertility and enabling new horizons to be opened up in the development of therapeutic targets and strategies to combat it,» explained Dr Subirán.
While Carlezon's research focuses on animal models, his findings have implications for humans.
The IOM committee left open the possibility that chimpanzees may be a necessary animal model to address future emerging or reemerging diseases, which raised the question of whether NIH will readdress its 17 - year - old ban on funding the breeding of chimpanzees for research.
The decision follows recommendations from an NIH advisory panel that said in January that the agency should curb research on chimps and instead «emphasize the development and refinement of other approaches, especially alternative animal models,» and move all but approximately 50 of the chimps to sanctuaries.
According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.
The U.S. government has lifted a temporary ban on research attempting to develop an animal model for the MERS (Middle East respiratory syndrome) virus, a deadly coronavirus spreading from camels to people in the Middle East.
University of Adelaide researchers in Australia, supported by the Invasive Animals Co-operative Research Centre, have developed a model of the likelihood of establishment of alien species of snakes and other reptiles if they are introduced to the wild, accidentally or on purpose.
A lot of research is currently done on animal models, and their findings may not translate to humans, he cautions.
«The development of this microfluidic lung model, as well as other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.
Assistant Professor Arindam Basu from NTU's School of Electrical and Electronic Engineering said the research team have tested the chip on data recorded from animal models, which showed that it could decode the brain's signal to the hand and fingers with 95 per cent accuracy.
Professor Bruno D'Agostino from the University of Naples said: «For many years, my research group has been working on the role of nociceptin in the regulation of airway responsiveness in animal models, and it is very interesting translating our results into clinic area regarding asthma, a disease that is forecast to grow over the next years.»
Sounds like science fiction, but new research in an animal model of hemophilia suggests that it can work - and now HD researchers are on the case.
Research Project Grant (R01) applications proposing to conduct mechanistic studies in humans and animal models on the relationships between alcohol abuse, circadian rhythms and sleep disorders.
In this project WBVR of SWR performs research on improvement of animal models for vaccine research specifically in neonate conditions.
Her research interests are focused on understanding the molecular mechanisms that regulate retinal tissue regeneration in a variety of animal models.
Research will aim to improve the predictive value of animal models for vaccine evaluation, provide consultancy on the selection of appropriate models, and develop innovative approaches to characterise in vivo antigen behaviour and host responses whilst reducing animal use.
Research Project Grant (R01) applications proposing to conduct mechanistic studies in humans and animal models on alcohol - induced transgenerational effects and the role of epigenetic inheritance in these effects.
Services currently offered: We offer contract research based on the well - characterised animal models and infrastructure described above, which has been used in several EU projects.
Dr. Amaral's interests include research involving multidisciplinary studies directed at determining the neuroanatomical, behavioral and electrophysiological organization and functions of brain systems that are involved in learning, memory, emotion and social behavior carried out on the human brain and on animal models.
General Product Information Obesity - High Fat Diets for Diet - Induced Obesity Models Metabolic Syndrome - Diet - Induced Metabolic Syndrome in Rodent Models Diabetes - High Fructose / Sucrose Diets for inducing Hypertriglyceridemia and Insulin Resistance in Rodents Atherosclerosis - Diet - Induced Atherosclerosis / Hypercholesterolemia in Rodent Models Hypertension - Phenotypic Expression of Hypertension in Rodent Models through Dietary Manipulation NAFLD (Non-alcoholic Fatty Liver Disease) Cancer - Creating a Clean Background for Oncology Research Test Compounds / Kaolin Pellets Diet and Immunology Focus: Arsenic in Grain - Based Laboratory Animal Diets and Effects on the Rodent Toxicological Phenotype Focus: The Importance of a Proper Control Diet
In addition to a detailed study of the mudskipper and development of a robot model that used the animal's locomotion techniques, the study also examined flow and drag conditions in representative granular materials and applied a mathematical model incorporating new physics based on the drag research.
Our work mainly involves research and clinical groups of Normandie developing programs in patients and animal models, to improve our understanding of the impact of cancer and its treatments on cognitive functions.
His research interests are focused on the molecular genetics of the inherited myopathies and neuromuscular junction disorders and the study of animal models of these disorders as a means to understand their pathophysiology as well as to develop means to monitor disease progression and therapeutic interventions.
More: A multidisciplinary approach: The Vanderbilt Brain Institute Psychopharmacology: Molecules of the mind fMRI: Watching the brain in action Cognitive neuroscience: A critical bridge Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
More: Psychopharmacology: Molecules of the mind fMRI: Watching the brain in action Cognitive neuroscience: A critical bridge Studying intellectual disabilities: Vanderbilt's legacy of brain science Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
The research team now concentrates on using CBS - based therapy in other animal infection models, e.g. urinary tract infection (UTI), hoping to offer a more extensive approach to combat with antibiotic resistant superbugs.
More: A multidisciplinary approach: The Vanderbilt Brain Institute Psychopharmacology: Molecules of the mind Cognitive neuroscience: A critical bridge Studying intellectual disabilities: Vanderbilt's legacy of brain science Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
Having previously published data on a variety of experimental mAbs against AS species in animal models -LRB-[16,20]; possibly [21]-RRB-, Prothena's Dale Schenk presented new data on additional experimental antibodies at SENS Research Foundation's Rejuvenation Biotechnology 2014 conference, roughly contemporaneous to its publication, [22] along with information specific to the humanized candidate PRX002, which is now being advanced into clinical trials.
More: A multidisciplinary approach: The Vanderbilt Brain Institute Psychopharmacology: Molecules of the mind fMRI: Watching the brain in action Cognitive neuroscience: A critical bridge Studying intellectual disabilities: Vanderbilt's legacy of brain science Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
More: A multidisciplinary approach: The Vanderbilt Brain Institute Psychopharmacology: Molecules of the mind fMRI: Watching the brain in action Studying intellectual disabilities: Vanderbilt's legacy of brain science Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
More: A multidisciplinary approach: The Vanderbilt Brain Institute fMRI: Watching the brain in action Cognitive neuroscience: A critical bridge Studying intellectual disabilities: Vanderbilt's legacy of brain science Animal brains: Models of the human condition The brain on trial: The MacArthur Foundation Research Network on Law and Neuroscience
You damn well better believe that there is research going on in animal models — what does she expect, that scientists should mutagenize human mothers and chop up baby brains for this work?
Slicer touches on a very significant problem for glucosepane research: no good animal models.
The third webinar, and the final one will focus on animal models of obesity and diabetes, both talking about genetic models, as well as dietary models and how they are used in basic research, but also in pharmaceutical and biotech research.
While Pollard's research focuses on understanding the microbiome through bioinformatics and modeling, other projects study human disorders such as diabetes and asthma, the impact of the ocean and soil on climate change, and the influence of plants, animals, and water on food production.
Dr. Ressler's lab focuses on translational research bridging molecular neurobiology in animal models with human genetic research on emotion, particularly fear and anxiety disorders.
This unique international event will provide the attendees with an innovative program focused on the best practices in the use of the mouse model for biomedical and basic research; this program also addresses the item of continuing professional education consistent with the new European directive requirement for lab animal protection in experiments.
New initiative called CRACK - IT launched; key aim is to develop new technologies (products, models and tools) for industry which reduce reliance on animal research.