Sentences with phrase «research using mice»

The first two types discussed were based on studies from human twins, whereas the third type was formulated based on research using mice.

The published study included research using mice and mouse cells.

Conversely, fundamental research using mouse models can identify genes associated with disease and provide insights into pathogenic mechanisms underlying environment - driven diseases, including infectious diseases and cancer.

Not exact matches

While we can't use sterile mice to make any definitive conclusions about humans, the twins study, published in the journal Science last year, provided clear evidence that the microbiome is involved in weight gain — something earlier research had only suggested.

Of course, there is still a long way to go before this particular method will be tested on humans (it was tested on mice), and an even longer way to go before it'll be used in medical therapies (if it ever will translate into therapies), but one thing is becoming clear: We need not compromise our moral principles and rush into government - funded embryo - destructive research.

TPA is used by scientists to produce skin tumors in mice for research.

The author discuses the dangers of pertussis and specifically that the same substance being used to cause brain inflammation in mice utilized for research.

The research, which used mouse foster nursing models, has important implications for vaccinating newborn babies.

«Each animal bred or used for research, whether a mouse, fish or monkey, is an individual capable of experiencing pain, suffering and distress.

The first and newest FDA - approved treatment of nusinersen doesn't completely cure the disease, so Sumner's research team wanted to see if using ASO - A in conjunction with nusinersen would further improve muscle form and function in mice with spinal muscular atrophy.

Scientists once shied away from naming research animals, and many of the millions of mice and rats used in U.S. research today go nameless, except for special individuals.

Her research shows that simply using quat - based cleaners in the same room as the mice was enough to cause birth defects.

A year before he published his results in 2017, research by a team in Japan led to the birth of live mouse pups using eggs the team made from adult skin cells.

Using the mouse as an experimental model, LMU neurobiologist PD Dr. Conny Kopp - Scheinpflug and her research group have now demonstrated that the activity of nerve cells in the auditory system has a direct effect on myelinization — higher levels of activity correlate with the formation of thicker myelin sheaths.

The ability of SIF - seq to use reporter assays in mouse embryonic stem cells to identify human embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities as Dickel explains.

Research published in the October 21 issue of Science Translational Medicine uses a virus to deliver an extra dose of the gene p11 to the adult mouse brain.

In the latest research, described online this week in the journal Cell Reports, Stelzer used the reporter system in mice to discover that imprinted methylation in developing and adult tissues is actively regulated rather than merely maintained in stable fashion.

The study, sponsored by the Office of Naval Research (ONR) Global, involved the use of Transcranial Direct Current Stimulation, or tDCS, on the mice.

In a previous study Hu's research team used neuron - disrupting molecules to prove the relationship between dmPFC activity and a mouse's decision to surrender to or push back against its cage mate in the tube task.

This is a highly limiting factor for research, because it complicates the annotation of data obtained by molecular techniques, and because it has been shown that gut microbiomes are to some extent specific to their host, and researchers have been using strains of other origin in mouse models.

«Using a genetic method, we inhibited MTF1 in the epileptic mice and as a result, the seizures in the animals were much rarer and weaker,» says lead author Dr. Karen M.J. van Loo who is conducting research in the team working with Prof. Becker.

For the research, the scientists used the platform to target colon macrophages in order to reduce inflammatory symptoms caused by Inflammatory Bowel Disease (IBD) in mouse models.

Several research groups have tried to clarify this issue using various methods to clear microglia from the brains of Alzheimer's mice to see how this would affect amyloid buildup.

Staff at underground mouse facilities would be working through the night to monitor tens of thousands of mice used in research projects from cancer to neurobiology.

Many universities and pharmaceutical companies are engaged in research and development using genetically modified mice that have certain genes manipulated to reproduce human diseases.

Professor Chayama and his research group used mice with «humanized» livers, and injected them with human blood.

New research on mice demonstrates a way to use designer bacteria as a non-invasive test for cancer.

Typical pain treatment research begins with an animal model — one that uses only male mice.

«However, a problem with almost all research on hematopoiesis in past decades is that it has been restricted to experiments in culture or using transplantation into mice,» says Professor Hans - Reimer Rodewald from the German Cancer Research Center (Deutsches Krebsforschungszentrumresearch on hematopoiesis in past decades is that it has been restricted to experiments in culture or using transplantation into mice,» says Professor Hans - Reimer Rodewald from the German Cancer Research Center (Deutsches KrebsforschungszentrumResearch Center (Deutsches Krebsforschungszentrum, DKFZ).

A dye used for more than a century to stain autopsied brain tissue can prevent the devastating effects of Huntington's disease in mice, new research shows.

(It exempts mice, rats, and birds used in research from regulation.)

St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu - infected mice.

«It also remains to be elucidated whether this phenomenon is particular for the mouse strain used in this study or is a more general phenomenon that also occurs in other genetic strains,» said Dr. Gerjo JVM van Osch, senior author of the Journal of Orthopedic Research article.

New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury.

The station crew later will unload the equipment and supplies inside the Dragon, including a glovebox - sized habitat holding 20 mice that will be used for microgravity research into bone density.

To test whether increased levels of Oprl1 could treat or prevent the mice's PTSD symptoms, Ressler and his colleagues used a newly developed compound from the Scripps Research Institute that activates the receptor.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in Human and Molecular Biology show, for the first time, using mice, that pluripotent stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.

Most animal studies of the disease are conducted with laboratory mice that have been genetically engineered and bred to model ALS, but for this research, investigators used rats with ALS because they more accurately portray the disease's variable course in humans.

New research in mice shows that the bacteria that cause ulcers establish colonies in stomachs using hydrogen gas produced farther along in the gut.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

«Using a mouse model of tuberculosis, we have shown lower doses of bedaquiline together with verapamil have the same antibacterial effect as the higher toxic doses,» says Shashank Gupta, Ph.D., a research fellow at Johns Hopkins.

The research team, led by Akiko Iwasaki, professor of immunobiology and Howard Hughes Medical Institute investigator, decided to investigate using mice models of herpes simplex virus - 1, the dominant cause of genital herpes in the United States.

In research published in the Journal of Bone and Mineral Research, Javed, a professor in the UAB School of Dentistry's Department of Oral and Maxillofacial Surgery, used a mouse model with mutations in both copies of the gene research published in the Journal of Bone and Mineral Research, Javed, a professor in the UAB School of Dentistry's Department of Oral and Maxillofacial Surgery, used a mouse model with mutations in both copies of the gene Research, Javed, a professor in the UAB School of Dentistry's Department of Oral and Maxillofacial Surgery, used a mouse model with mutations in both copies of the gene for Sp7.

The current JBMR study extended that research by using palovarotene in a mouse model carrying the same human gene mutation that causes FOP.

To further identify the role of TAZ, the research team studied breast tissue at different stages of development using two groups of mice: a control group with the TAZ gene and an experimental group of knock - out mice with the TAZ gene deleted.

The scientists, including Florian Reisinger from the Institute of Virology (HMGU) and Dr. Kristian Unger from the Research Unit Radiation Cytogenetics (HMGU) showed this using mouse models.

«Using a genetic mouse model of DIPG, we found that the histone mutation turns off p16, which is a gene that acts like a break on dividing cells,» says senior author Oren J. Becher, MD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago.

«Using models such as zebrafish and neonatal mice that regenerate their hearts naturally, we can begin to identify important molecules that enhance heart repair,» said Ellen Lien, PhD, of The Saban Research Institute of Children's Hospital Los Angeles.

However, new research from Carnegie's Lei Lei and Allan Spradling demonstrates that adult mice do not use stem cells to produce new eggs.