In 1950, while
a researcher at the pharmaceutical company Burroughs Wellcome, Elion synthesized 6 - mercaptopurine, a treatment for leukemia that dramatically changed cancer therapy.
Not exact matches
In his role as
researcher, he developed a potential drug to treat different types of immune diseases and was able to accompany the molecule through the next stages?something most scientists
at pharmaceutical companies are not able to do.
Now
researchers at the University of Plymouth, working in partnership with
pharmaceutical company AstraZeneca, have for the first time successfully cultured and maintained cells from the guts of rainbow trout, a recommended fish species for toxicological studies.
A 2003 survey, led by Scott Kim, an associate professor in the bioethics program
at the University of Michigan
at Ann Arbor, showed that if participants were told that a
researcher or institution testing a treatment was being funded by the
pharmaceutical company that made the drug, 40 percent would be more willing to participate — a finding Kim chalks up to an appreciation for up - front honesty.
On the industry side, Lilly, headquartered in Indianapolis, Indiana, has a program that encourages scientists
at the
pharmaceutical company to collaborate with university
researchers.
What changed the scene was an immunosuppressant molecule called cyclosporin, developed by
researchers at Sandoz, the Swiss
pharmaceutical company.
The
researchers used a version of this approach to isolate and grow new bacterial colonies — many scooped out of soil in the backyard of microbiologist Losee Ling, who leads research and development
at the startup
company NovoBiotic
Pharmaceuticals, formed to commercialize their approach.
Clinical
researchers can end up anywhere from academia, where posts are based
at university medical school research units or
at hospital research units, to
pharmaceutical or biotech
companies, or in contract research organisations (CROs), which carry out clinical trials for drug or biotech
companies.
William Pardridge, a
researcher at the University of California, Los Angeles, who has long criticized biotech and
pharmaceutical companies for not developing strategies to get therapies across the blood - brain barrier, says Genentech may be the first major
company to do so.
Today, CCP4 has around 2 million lines of code, dozens of active contributors and thousands of users worldwide, including expert crystallographers, academic
researchers interested in solving structures, and scientists doing drug development
at pharmaceutical companies.
Sanjay Gurunathan, representing a partnership of
researchers,
pharmaceutical companies and funders aimed
at taking RV144 forward, said there had been some exciting post-trial analysis.
Intrigued by the plant's traditional use,
researchers at Hallym University College of Medicine in Seoul, Institute of Natural Medicine, and Scigenic, a Korean phyto -
pharmaceutical company, suspected that one particular constituent of Angelica gigas had powerful pharmacological activity.