Sentences with phrase «researchers know this drug»

While the researchers know this drug boosts the ability of diseased mitochondria to fuse to one another, Dorn said it's possible this is not what lets them move.

The researchers knew the drug — an alkylated imino sugar called NB - DNJ — inhibits an enzyme involved in sperm production, so they investigated further.

Not exact matches

Better known to nightclubbers as ecstasy, the euphoria - inducing drug MDMA appears to alleviate Post-Traumatic Stress Disorder (PTSD) in war veterans, firefighters, and police officers, researchers said Wednesday.

But the researchers wanted to know if the drug, when combined with statin treatment, could also reduce the risk of heart disease in people with type 2 diabetes.

The researchers also described the full gene repertoires for known drug target families.

A new study published by researchers from the University of Illinois at Chicago suggests that the drug oseltamivir — commonly known as Tamiflu — does not cause an increased risk of suicide in pediatric patients.

Like many drugs in new indications, its effect was discovered by accident: researchers knew that quitting smokers were often depressed, and so they began experimenting with the drug as a means to alleviate depression, not addiction.

The big breakthrough came in 1996, when researchers realised that the best way to suppress HIV replication was to use a combination of drugs — an approach known as highly active antiretroviral therapy (HAART).

In a blinded test, researchers don't know whether they are giving patients the drug being tested or fake medicine.

Countries communicate more efficiently about common medical problems thanks to her, and researchers know that drugs — and viruses — that appear to have little or no side - effects on pregnant women can be devastating to their developing babies.

Now that researchers know from their cell studies that this family of receptors can essentially flip its own switch, they can use that information to design drugs to prevent that from happening when it shouldn't.

Researchers from the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester, who led the study, warned that failure to take the drugs correctly, known as «non-adherence», reduced their effectiveness and may lead to a worsening of patients» disease.

The researchers plan to further test the drugs against Ebola, which has a high fatality rate and no known cure.

Because the subjects in these closely watched studies are at such a high risk, researchers should know within the next few years if the experimental drugs will halt or delay the onset of the disease.

Knowing more about spindles could also help researchers design drugs or behavioral techniques that deepen sleep, says Ellenbogen.

Many researchers believe that psychedelic effects are driven in large part by expectations of the experience so neither monitors nor subjects knew when they would be given the psychoactive drug.

Researchers wanted to know if the benefits of the drug go beyond clearing the skin.

Ketamine was developed as an anesthetic, but is better known publicly for its abuse as the party drug Special K. Researchers are now seeking alternatives because ketamine can produce side effects that include hallucinations and the potential for abuse — limiting its utility as an antidepressant.

Now, researchers who've studied how perceptions of meaning change when people take the psychedelic drug known as LSD have traced that sense of meaningfulness to particular neurochemicals and receptors in the brain.

To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the researchers had detected in distant metastases, they treated tumor cells from different sites in a single patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not used in humans because of its severe side effects.

Led by the University of Surrey, a team of researchers from the Netherlands Forensic Institute (NL), the National Physical Laboratory (UK), King's College London (UK) and Sheffield Hallam University (UK), used different types of an analytical chemistry technique known as mass spectrometry to analyse the fingerprints of patients attending drug treatment services.

Today in Circulation, the journal of the American Heart Association, Vanderbilt University researchers published findings that the drug — a monoclonal antibody known as SYN0012 — shows promise in keeping heart valve leaflets supple.

(Neither the children's parents nor the researchers who assessed the children knew who received the actual drug.)

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA - approved for chemical abortion, prevents the growth of vestibular schwannoma (also known as acoustic neuroma) cells.

To determine how the brain encodes this drug - related behavior, the researchers need to know exactly which neurons are involved.

The researchers, led by neuroscientist Andreas Meyer - Lindenberg, studied a total of 142 men and women lacking any known history of mental illness or drug or alcohol abuse.

The researchers Miquel Duran and Patrick Aloy collated all the drugs that cause each known SE.

The Federal Drug Administration has approved few drugs for long - term weight loss, and some are no longer marketed because of safety issues, the researchers said.

Even before they knew the actual identity of -LRB-- secretase, drug companies had already been developing compounds that block the enzyme's activity; but now that researchers have actual secretase enzymes in hand, they can look for more specific and powerful inhibitors.

«It's well known that both drinking and other drug use are linked to risky driving,» said lead researcher Yvonne Terry - McElrath, of the University of Michigan's Institute for Social Research in Ann Arbor.

When developing a new drug, researchers identify drug targets based on what they know about the biology of the disease, and then create compounds that affect those targets.

Using newly discovered information, the researchers made significant advances in developing a family of drug candidates that target a receptor known as peroxisome proliferator - activated receptors gamma (PPARγ), a key regulator of stem cells controlling bone formation and bone resorption and a master regulator of fat.

As proof of principle, the researchers demonstrate the production of diphenhydramine hydrochloride (common trade name Benadryl ®, often used to treat allergies), lidocaine hydrochloride (a common local anesthetic and antiarrhythmic drug), diazepam (commonly known as Valium ®), and fluoxetine hydrochloride (a widely used antidepressant, e.g. Prozac ®).

Lead researcher and author of the paper Dr Rebecca Bromley, of The University of Manchester's School of Biological Sciences, said expectant mothers had to know the possible impacts their drug regimes may have on unborn children.

A patent application for a drug that could destroy the deadly childhood disease known as acute lymphoblastic leukemia — and potentially other cancers as well — has been submitted by researchers at Sandia National Laboratories, the University of Maryland and the MD Anderson Cancer Center in Houston.

The researchers saw that among the PTSD group, who were all taking the drug paroxetine (sold as Paxil), the patients who showed the most improvement from the SSRI were those who showed the least activation, prior to treatment, of a brain area called the right ventrolateral prefrontal cortex, also known as the inferior frontal gyrus.

The researchers began to wonder whether a phenomenon known as RNA interference or RNAi could be the cause of this unstable drug resistance.

Researchers have found that we're more likely to experience negative side effects when we take a drug we think is pricier — a flip side of the placebo effect known as the «nocebo» effect.

For example, researchers would like to know how the drug affects dystrophin production in muscles throughout the limbs and whether some muscles may get a bigger boost than others.

In addition to assisting researchers search for relationships between microRNAs and their genetic targets, the database includes drugs known to affect these microRNAs and also lists diseases associated with microRNAs.

Ishmael said even if coibamide A itself can not enter the brain or turns out to have adverse side effects, knowing its structure and mechanism of action can help researchers develop new drugs that mimic coibamide A's effects.

To test the potential of the system as a drug - screening tool, the researchers exposed the differentiating cells to thalidomide, a drug known to cause severe birth defects.

In multiple trials of mice with both active and chronic TB infections, researchers report that one version of the new drug — an analog known as 1599 — was as good as or better than current TB drugs at reducing levels of the bacteria in the lungs of mice.

«We've always known that electronic dance music party attendees are at high risk for use of club drugs such as ecstasy or Molly, but we wanted to know the extent of opioid use in this population,» said CDUHR researcher Joseph Palamar, PhD, MPH, the study's lead author and an associate professor of population health at NYU School of Medicine.

Curing babies born with HIV is no longer out of the question: An HIV - positive newborn treated immediately with antiviral drugs is now 3 years old and free of infection, researchers announced in March and confirmed in a paper in October.

The researchers have focused primarily on a drug called glibenclamide (also known as Glyburide), which inhibits Sur1.

Yet when Evans and his colleagues recently gave a PPAR & # 948 - boosting drug to normal adult mice, the rodents developed no greater stamina than nondoped counterparts — until the researchers had the animals combine the drug with a workout routine.

One of the problems facing researchers is how to ensure that participants and investigators don't know whether they are dealing with the drug or a placebo.

PD -1-blocking agents such as nivolumab, pembrolizumab and atezolizumab are part of a class of drugs known as checkpoint inhibitors, and many cancer researchers are now trying to figure out how to enhance their activity by combining them with other types of drugs.

At this year's San Antonio Breast Cancer Symposium, UNC Lineberger researchers and collaborators shared the outcomes of their investigation into the incidence of brain metastasis after a series of drugs were approved to treat HER2 - positive metastatic breast cancer, starting with trastuzumab, also known as Herceptin, in the United States in 1998.