While Dr. Joseph led this study, he is a part of a team of international
researchers studying the drug, which he says has offered patients with metastatic melanoma «truly impressive results.»
To find out whether an oral form of minoxidil can remodel the vessel's wall to reduce blood vessel stiffness and enhance blood flow to the brain,
researchers studied the drug's effects in mice.
Not exact matches
A peer - reviewed
study by
researchers at the University of British Columbia and Simon Fraser University, published recently in The International Journal of
Drug Policy, pegged the retail value of marijuana consumption in B.C. alone at between $ 443 million and $ 564 million.
After fighting unsuccessfully to reverse generic
drug laws last year, and the sudden resignation of its CEO, Shoppers Drug Mart has suffered a 17 % drop in «brand value,» to $ 2.6 billion, according to a study conducted by researcher Interbr
drug laws last year, and the sudden resignation of its CEO, Shoppers
Drug Mart has suffered a 17 % drop in «brand value,» to $ 2.6 billion, according to a study conducted by researcher Interbr
Drug Mart has suffered a 17 % drop in «brand value,» to $ 2.6 billion, according to a
study conducted by
researcher Interbrand.
«By having 1 million individual users you can get to a scale where
researchers are running data queries through 23andMe, where
drug studies leverage our data, and where individuals can more easily be connected to
studies that could benefit them,» Wojcicki said.
The
study, just published in Science, showed that the creation of what the
researchers are calling microtumors can help predict
drug effectiveness in cancer patients better than the current standard method of testing the
drugs on rodents.
The institute, which includes over 40 laboratories and more than 300
researchers, said the research would focus on modifying a patient's own immune system T - cells to target a tumor,
studying ways to boost patient response to current immunotherapy
drugs.
For future
studies, they suggested,
researchers should test the performance of doped chess players given a much longer time limit, so the
study could isolate the positive effects of brain
drugs.
The Bayer
researchers were drowning in bad
studies, and it was to this, in part, that they attributed the mysteriously declining yields of
drug pipelines.
As recently as February
researchers with the US Food and
Drug Administration ran a
study that mimicked the small doses of BPA that people may come into contact with.
In this
study, and in opposition to findings elsewhere, higher levels of social support were associated with greater depressive symptomatology, leading
researchers to speculate that for low - income men the perceived costs of reciprocity may have deterred them from utilizing available support; or that peer groups may have influenced their alcohol or
drug use, or placed demands on their resources (Anderson et al, 2005).
Researchers have shown that many teens are incorrect about what their peers are doing in the areas of sex,
drugs and
studying.
The transgender woman in this
study continued to take spironolactone, and androgen blockade, while breastfeeding (the
researchers noted an insignificant trace of the
drug was found in her breastmilk).
The
researchers also found that many of the
studies showed that children who had restrictive parents were less likely to get involved in negative behaviors such as cyberbullying,
drug use, vandalism, and theft, and were less likely to have poor body image — factors the
study authors called «negative consumer socialization outcomes.»
These are some of the recommendations contained in a
study produced by Spanish
researchers on methods for detecting medicines and
drugs in breast milk.
She also instinctively bends her legs completing the protective space around the baby, making it impossible for another person to roll onto the baby without first coming into contact with her legs.15, 16 A breastfeeding mother who co-sleeps with her baby (and has not consumed alcohol, illegal or sleep - inducing
drugs or extreme fatigue) also tends to be highly responsive to her baby's needs.17, 18
Studies show more frequent arousals in both mothers and babies when they co-sleep, and some
researchers have suggested that this may be protective against sudden unexpected infant deaths.19 — 21 Babies are checked by their mother and breastfeed more frequently when co-sleeping than when room - sharing.22, 23
Physical punishment is associated with a range of mental health problems in children, youth and adults, including depression, unhappiness, anxiety, feelings of hopelessness, use of
drugs and alcohol, and general psychological maladjustment.26 — 29 These relationships may be mediated by disruptions in parent — child attachment resulting from pain inflicted by a caregiver, 30,31 by increased levels of cortisol32 or by chemical disruption of the brain's mechanism for regulating stress.33
Researchers are also finding that physical punishment is linked to slower cognitive development and adversely affects academic achievement.34 These findings come from large longitudinal
studies that control for a wide range of potential confounders.35 Intriguing results are now emerging from neuroimaging
studies, which suggest that physical punishment may reduce the volume of the brain's grey matter in areas associated with performance on the Wechsler Adult Intelligence Scale, third edition (WAIS - III).36 In addition, physical punishment can cause alterations in the dopaminergic regions associated with vulnerability to the abuse of
drugs and alcohol.37
This
study, performed by Swansea University
researchers of 48,000 women who gave birth to healthy (singleton) babies over 10 years, found that women who took these
drugs had a 7 % chance of lowered milk production.
Since then an advisory committee to the US Food and
Drug Administration has been
studying whether the process is safe, after a Portland
researcher said he had conducted the technique successfully on monkeys - and now wanted to begin trying it on humans.
While ZMapp seemed to help more people survive an Ebola infection, it narrowly missed the statistical threshold that
researchers set to prove the
drug's effectiveness, according to the new
study, published in the New England Journal of Medicine.
The sacks could be used as a new way to deliver
drugs, say the
researchers, whose
study appears in the current issue of Science.
A new
study published by
researchers from the University of Illinois at Chicago suggests that the
drug oseltamivir — commonly known as Tamiflu — does not cause an increased risk of suicide in pediatric patients.
Researchers looked at data on 74 300 patient who received metformin and sulfonylurea, another common diabetes
drug, over a 25 - year
study period.
The
researchers injected either the antisense
drug or a placebo into the
study participants» spinal fluid — a 20 - minute procedure similar to those that deliver epidural anesthesia to women in labor.
For this
study the
researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different
drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the
drug's impacts.
Further, the effect was so strong in some participants that it was nearly comparable to that achieved with
drugs specifically prescribed to treat gout, a new
study led by Johns Hopkins
researchers shows.
In the
study, the
researchers loaded a hydrogel — a half - inch disc made of a biodegradable sugar naturally found in the human body — with
drugs that activate dendritic cells.
In the
study, published online today by Science Translational Medicine,
researchers removed breast tumors from mice and placed biodegradable gels containing an immune - stimulating
drug in the resulting empty space.
In a recent
study, working with a team of
researchers, Danino demonstrated that bacteria in pancreatic tumors degrade a chemotherapy
drug — Gemcitabine — most commonly used to treat patients who have pancreatic cancer.
An experimental
drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a
study led by
researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
The
researchers then
studied wastewater samples from 10 cities throughout the United States, testing for 14 illicit, prescription, and nonprescription
drugs including heroine, cocaine, methamphetamine, and oxycodone.
A new
study by
researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer cells develop resistance to a class of
drugs called fibroblast growth factor receptor (FGFR) inhibitors.
Now that
researchers know from their cell
studies that this family of receptors can essentially flip its own switch, they can use that information to design
drugs to prevent that from happening when it shouldn't.
Tissue engineering provides a more practical means for
researchers to
study cell behavior, such as cancer cell resistance to therapy, and test new
drugs or combinations of
drugs to treat many diseases.
In two
studies, Freiburg
researchers have made new discoveries concerning the relationship between CML and Gab2 and
drugs that can break a particular resistance to Gab2 in CML cells.
In the short term, such artificial tissues could help
researchers study disease processes and test new
drugs in the lab.
The
researchers also plan to use this technology to
study drug resistance and are developing additional platforms to guide decision making in the clinic.
As an MSL, he spent most of his time synthesizing information from
drug studies and preparing and delivering symposia and seminars to physicians,
researchers, and medical societies.
Researchers from the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester, who led the
study, warned that failure to take the
drugs correctly, known as «non-adherence», reduced their effectiveness and may lead to a worsening of patients» disease.
Next,
researchers would like to
study how the two -
drug approach works in humans, although no clinical trials have yet been designed or scheduled.
Anti-malaria
drugs were routinely administered to all patients seen at the Treatment Unit during the Ebola outbreak and had no bearing on the increased survival in Plasmodium - infected patients in the
study, the
researchers say.
He notes that the
drug may reduce the anxiety and insomnia that often accompany alcohol withdrawal, which might ease the transition to sobriety, but adds that
researchers can not accurately predict who might benefit from the
drug absent a larger
study.
Patients with chronic wounds who never receive opioids heal faster than those who do receive the
drugs, according to a new
study by George Washington University (GW)
researcher Victoria Shanmugam, M.D.
The
researchers will soon launch a three - month clinical
study to test sperm counts in men taking the
drug.
Because the subjects in these closely watched
studies are at such a high risk,
researchers should know within the next few years if the experimental
drugs will halt or delay the onset of the disease.
They are helping
researchers study how
drugs work against the swine flu virus and how space and time warp around colliding black holes.
According to the
study's lead
researcher, geneticist Albert La Spada of the University of California, San Diego, «the prospect of an oral
drug is conceivable.»
The upshot, say Workman and others, is that many probes produce spurious results that can lead
researchers to wrong conclusions about the proteins and
drug molecules they are
studying.
The discovery of an unexpected biochemical link within tumor cells should lead to clinical trials for experimental
drug treatments that indirectly target myc and that already are being evaluated in human
studies, the
researchers said.
Many patients and physicians assume that the safety and effectiveness of newly approved
drugs is well understood by the federal Food and
Drug Administration (FDA)-- but a new
study by
researchers at Yale School of Medicine shows that the clinical trials used by the FDA to approve new
drugs between 2005 and 2012 vary widely in their thoroughness.