Sentences with phrase «researchers switched these genes»

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Using gene - sequencing technology, researchers established that the precise segment of the pup's DNA «switched on» by the act of grooming was the part that controlled the future function of the hippocampus, which processes stress hormones.
In a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genome.
Working with this hypothesis, the researchers conducted a statistical analysis of the CX3CR1 gene in over 7000 schizophrenia and autism patients and healthy subjects, finding one mutant candidate, a single amino acid switch from alanine to threonine, as a candidate marker for prediction.
Because the prion - forming protein identified in the study normally functions as a regulator of gene activity, the researchers say their discovery raises the possibility that when it switches to a prion state, it could alter genetic expression and bacterial behavior.
Researchers are developing molecular switches that can inactivate transplanted genes, paving the way for safer gene therapies.
Issued last March to researchers at a little - known cotton seed company called Delta & Pine Land (D&PL) and the U.S. Department of Agriculture, the patent covers a technique for transferring three genes along with their genetic on switches into the seeds of genetically improved plants.
Potentially explaining why even healthy brains don't function well with age, Salk researchers have discovered that genes that are switched on early in brain development to sever connections between neurons as the brain fine - tunes, are again activated in aging neuronal support cells called astrocytes.
In 2002 Joslin researcher Steven Shoelson knew that salicylates block the action of a protein called NFkB, a genetic master switch in the liver that helps launch a cascade of genes that cause the chronic, low - grade inflammation associated with diabetes.
With chronically infected mice as their model, the researchers used a new technology called ATAC - seq to map the regulatory regions of the genome — the sections of DNA involved in switching genes on and off — in the animals» exhausted and functional CD8 + T cells.
To see if the gene, Gp - 9, was really a switch for social behavior, the researchers raised fire ants in captivity.
A team of researchers has developed a light - activated switch that can turn genes on and off in mammalian cells.
Researchers showed that the genes turned on by the switch remained active for several hours in several mammalian cell lines even after a short light pulse.
Writing online in the journal Molecular Cell, a team of researchers from the University of Wisconsin - Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
The researchers engineered a strain in which a Synechococcus gene normally turned on during photosynthesis signals its activity by switching on the gene for luciferase, an enzyme from another bacterium that drives a light - emitting chemical reaction.
The researchers used tools of epigenomic analysis to trace the specific epigenetic switches controlling each of thousands of genes in both mouse and human retinal cells as the cells progressed through development.
Researchers have identified many of Short - root's gene targets, but weren't sure what controlled the Short - root master switch itself to kick off the cascade.
Mind controls: Putting a light switch in the brain With optogenetics, researchers can implant optical fibres to control genetically modified animals — could gene therapy bring it to humans?
Light played a key role in the experiment because it allowed the researchers to switch on genes that they had added to the yeast cells.
The super-enhancers switched on known cancer genes, including genes like ALK, MYC, SMO and OTX2 that are associated with medulloblastoma, researchers reported.
Researchers have developed a set of genetic switches that can be built into engineered organisms, to control the function of genes they need to survive.
Writing online Nov. 23 in the journal Molecular Cell, a team of researchers from the University of Wisconsin — Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
But the researchers also put a copy of the Myd88 gene near a special «promoter» sequence of DNA that gets switched on during early embryonic development.
RNA interference, something Kissler learned as a post-doc at MIT, is a process that uses strands of genetic material called RNA to inhibit the expressions of genes — meaning researchers can manually decide which genes get turned on or off and when by using RNA to block the pathways that lead to the genes» switches.
To keep those residual toxin levels at bay, the researchers included a second gene in their kill switch, which produces low levels of an anti-toxin that can neutralize small amounts of the toxin.
In the most detailed large - scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off.
With the complete sequence of the N. meningitidis genome in hand, researchers can now choose to target genes that lack switch regions.
The researchers believe noise could play a role, so they combine single - molecule analysis with time - lapse movies of individual cells to track random activity in many different genes as the cells switch states.
Researchers have identified anti-CRISPR proteins that can act as an off switch for the gene editing system, making it safer to use.
The researchers found that portions of the FTO gene were involved in switching on a promoter of IRX3, which encodes a transcription factor and is highly conserved in mice, zebrafish, and humans.
Researchers in the US, China and Taiwan have developed a new systems biology model that mimics the process of wood formation, allowing scientists to predict the effects of switching on and off the 21 (at least) pathway genes involved in producing lignin, a primary component of wood.
The idea of «switching off» the cause of Huntington's disease was one of the first thoughts that popped into researchers» heads when the HD gene was discovered in 1993.
Most of these genes are silenced, or unexpressed, but the researchers demonstrate that this gene silencing can be switched on and off frequently.
Researchers found that particles in exhaust from cars and trucks can cause epigenetic changes — alterations that affect how genes are switched on and off without changing the DNA sequence itself.
Using the extensive St. Jude genomic database, researchers searched for other genes that were abnormally switched on in a virulent form of AML that is driven by an oncogene called MYCN.
Other researchers postulate that the muscle volumizing effect of creatine might switch on a gene responsible for IGF - 1 production.
In September 2012 researchers announced they had identified the gene that switches between mackerel and classic tabby patterns.
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